Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, ...
To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Matsuzawa, A, Murakami, M, Atsumi, G, Imai, K, Prados, P, Inoue, K, ...
Here we show that secretory phospholipase A2 (sPLA2) that is immunochemically indistinguishable from type II sPLA2 is (i) stored in neuroendocrine cells, (ii) released in response to...
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Hanabuchi, S, Koyanagi, M, Kawasaki, A, Shinohara, N, Matsuzawa, A, Nishimura, Y, ...
To investigate the mechanisms of T-cell-mediated cytotoxicity, we estimated the involvement of apoptosis-inducing Fas molecule on the target cells and its ligand on the effector cells. When...
Involvement of Fas in regression of vaginal epithelia after ovariectomy and during an estrous cycle.
Suzuki, A, Enari, M, Eguchi, Y, Matsuzawa, A, Nagata, S, Tsujimoto, Y, ...
Fas, also called APO-1, belongs to the tumor necrosis factor/nerve growth factor receptor family and transmits an apoptotic signal within the cell by binding to the Fas ligand. Fas has been...
Matsuzawa, A, Murakami, M, Atsumi, G, Imai, K, Prados, P, Inoue, K, ...
Here we show that secretory phospholipase A2 (sPLA2) that is immunochemically indistinguishable from type II sPLA2 is (i) stored in neuroendocrine cells, (ii) released in response to...
Takamoto, M, Wang, Z X, Watanabe, N, Matsuzawa, A, Nariuchi, H, Sugane, K
Mutant mice deficient in CD4+ T cells and their normal and heterozygous littermates were infected with Toxocara canis, and compared for eosinophilia, total and Toxocara-specific immunoglobulin E...
Matsuzawa, A, Moriyama, T, Ogata, Y, Katagiri, T, Kimura, M
The new mutation at the lpr locus, lprcg, induces massive lymphoproliferation characterized by the selective expansion of CD4-, CD8-, B220+, Thy-1+ cells or double-negative T lymphocytes and...
Nephritogenicity of the lprcg gene on the MRL background.
Kimura, M, Ogata, Y, Shimada, K, Wakabayashi, T, Onoda, H, Katagiri, T, ...
The novel lymphoproliferative and autoimmune lprcg gene, originally discovered in the CBA/K1Jms (CBA) strain of mice, was transferred onto the MRL/MpJ (MRL) strain background, and the resultant...
Kimura, M, Mohri, H, Shimada, K, Wakabayashi, T, Kanai, Y, Matsuzawa, A
CBA/KlJms-lprcg/lprcg mice with a novel mutation producing systemic lymphoproliferation were investigated for their serological and histological characteristics. The mutant mice showed elevated...
Zhang, Y, Yasuda, T, Wang, C R, Yoshimoto, T, Nagase, H, Takamoto, M, ...
The role of CD4 molecules in the autoimmune and lymphoproliferative syndrome caused by murine Fas mutations was studied using the novel systemic lupus erythematosus (SLE) model, MRL-Faslprcg/Faslprcg...
Warnock, R.A., Campbell, J.J., Dorf, M.E., Matsuzawa, A., McEvoy, L.M., Butcher, E.C.
Chemokines have been hypothesized to contribute to the selectivity of lymphocyte trafficking not only as chemoattractants, but also by triggering integrin-dependent sticking (arrest) of circulating...
Wang, C-R, Hino, A, Yoshimoto, T, Nagase, H, Kato, T, Hirokawa, K, ...
Delayed-type hypersensitivity (DTH) is an important in vivo manifestation of cell-mediated immunity. We examined the DTH response to methylated bovine serum albumin of a novel mutant strain of mice...
Progression from hormone dependence to autonomy and angiogenesis in mouse mammary tumours.
Oikawa, T., Matsuzawa, A., Iwaguchi, T.
The transplantable pregnancy-dependent mammary tumour (TPDMT-4), the related hormone-dependent (TPDMT-4EP) and autonomous (T4-0I320 and T4-0I96) subline tumours, and the mammary glands from DDD mice...