A. Mazumder

Publication List Details

Period

2003 - 2008

Number

29

Co-Authors

Toxicological Evaluation And Antinociceptive Effects Of Wrightia tomentosa In Mice (2008)

Nagarajan, K, Mazumder, A, Ghosh, L K

Acute toxicity testing and the antinociceptive activity in mice of ethanolic extract of Wrightia tomentosa leaves and bark were carried out. The bark extract (400mg/kg) exhibited maximum...

Short communication: In Vitro Antibacterial Activity of Leaf and Root Extracts of Clitoria ternatea Linn. (2008)

Mazumder, A, Roy, P, Mazumder, R

The methanol extracts of the leaves and root of Clitoria ternatea Linn. were tested for their antibacterial activity against different pathogenic drug resistant Gram-positive and Gram-negative...

Essential Oil Composition, Antibacterial and Antioxidant Activities of Four Mentha Species Growing in Ethiopia (2008)

Getahun, Z, Asres, K, Mazumder, A

The essential oils obtained by hydrodistillation from the leaves of Mentha arvensis L., M. longifolia L., M. piperita L., and M. spicata L., were analyzed by gas chromatography (GC-FID) and gas...

Benthic foraminifera as proxy for oxygen-depleted conditions off the central west coast of India (2007)

Nigam, R., Mazumder, A., Henriques, P.J., Saraswat, R.

In order to study the response of benthic foraminifera, especially the rectilinear bi- and tri-serial benthic foraminifera (RBF) to oxygen-depleted conditions from the Arabian Sea off central west...

Distribution of benthic foraminifera within oxygen minima zone, off central west coast, India (2003)

Mazumder, A., Henriques, P.J., Nigam, R.

A total of 128 surface sediment samples (76 grab and 52 core top samples) were analyzed for benthic foraminiferal contents from the region off Goa, India in the eastern Arabian Sea upto a water depth...

Role of 12 S mitochondrial gene on dimorphism and coiling direction in benthic foraminiferal species Pararotalia nipponica (2003)

Saraswat, R., Mazumder, A., Kurtarkar, S.R., Nigam, R., Ganguly, A.

Despite the extensive use of foraminiferal proxies for paleoclimatic reconstructions, the question how and why morphologic variations of foraminifera are regulated by climatic changes remains a...

Life spans of planktonic foraminifers: New sight through sediment traps (2003)

Nigam, R., Saraswat, R., Mazumder, A.

Determinig the life spans of planktonic foraminifera is vital in view of their increasing use for palaeoclimtic studies. Till date all the estimates about life span of planktonic foraminifers are...

Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.

Mazumder, A, Cooney, D, Agbaria, R, Gupta, M, Pommier, Y

The effects of 3'-azido-3'-deoxythymidine (AZT) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have...

A transcription inhibitor specific for unwound DNA in RNA polymerase-promoter open complexes.

Mazumder, A, Perrin, D M, Watson, K J, Sigman, D S

The kinetically component open complexes formed at prokaryotic and eukaryotic transcription start sites are efficiently nicked by the chemical nuclease activity of the 2:1...

A high throughput method to investigate oligodeoxyribonucleotide hybridization kinetics and thermodynamics.

Mazumder, A, Majlessi, M, Becker, M M

We describe a high throughput microtiter-based assay to measure binding of oligodeoxyribonucleotides to nucleic acid targets. The assay utilizes oligodeoxyribonucleotide probes labeled with a highly...

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1.

Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...

T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...

Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors.

Neamati, N, Mazumder, A, Zhao, H, Sunder, S, Burke, T R, Schultz, R J, ...

A majority of reported human immunodeficiency virus type 1 integrase (HIV-1 IN) inhibitors are polyhydroxylated aromatic compounds containing two phenyl rings separated by aliphatic or aromatic...

Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase.

Mazumder, A, Pommier, Y

We have examined the activities of HIV-1 integrase on substrates containing mismatches, composed of deoxyuridine at different positions in either the processed or nonprocessed strand of viral DNA,...

Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction.

Hawkins, M E, Pfleiderer, W, Mazumder, A, Pommier, Y G, Balis, F M

We have synthesized a highly fluorescent (quantum yield 0.88) guanosine analog, (3-methyl-8-(2-deoxy-beta-D-ribofuranosyl) isoxanthopterin (3-Mi) in a dimethoxytrityl, phosphoramidite protected form,...

Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that...

Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3'-processing and choice of nucleophile by HIV-1 integrase.

Mazumder, A, Gupta, M, Pommier, Y

We present evidence suggesting that the 3'-processing activity of HIV-1 integrase is dramatically affected by electrostatic and/or steric perturbations 3' to the conserved CA dinucleotide. When the...

Probing the active site residues in aromatic donor oxidation in horseradish peroxidase: involvement of an arginine and a tyrosine residue in aromatic donor binding.

Adak, S, Mazumder, A, Banerjee, R K

The plausible role of arginine and tyrosine residues at the active side of horseradish peroxidase (HRP) in aromatic donor (guaiacol) oxidation was probed by chemical modification followed by...

Inhibition of human immunodeficiency virus type 1 integrase by 3'-azido-3'-deoxythymidylate.

Mazumder, A, Cooney, D, Agbaria, R, Gupta, M, Pommier, Y

The effects of 3'-azido-3'-deoxythymidine (AZT) and three of its intracellular metabolites, azido- thymidine mono-, di-, and triphosphates, on the human immunodeficiency virus type 1 integrase have...

A transcription inhibitor specific for unwound DNA in RNA polymerase-promoter open complexes.

Mazumder, A, Perrin, D M, Watson, K J, Sigman, D S

The kinetically component open complexes formed at prokaryotic and eukaryotic transcription start sites are efficiently nicked by the chemical nuclease activity of the 2:1...

A high throughput method to investigate oligodeoxyribonucleotide hybridization kinetics and thermodynamics.

Mazumder, A, Majlessi, M, Becker, M M

We describe a high throughput microtiter-based assay to measure binding of oligodeoxyribonucleotides to nucleic acid targets. The assay utilizes oligodeoxyribonucleotide probes labeled with a highly...

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1.

Ojwang, J O, Buckheit, R W, Pommier, Y, Mazumder, A, De Vreese, K, Esté, J A, ...

T30177, an oligonucleotide composed of only deoxyguanosine and thymidine, is 17 nucleotides in length and contains single phosphorothioate internucleoside linkages at its 5' and 3' ends for...

Diarylsulfones, a novel class of human immunodeficiency virus type 1 integrase inhibitors.

Neamati, N, Mazumder, A, Zhao, H, Sunder, S, Burke, T R, Schultz, R J, ...

A majority of reported human immunodeficiency virus type 1 integrase (HIV-1 IN) inhibitors are polyhydroxylated aromatic compounds containing two phenyl rings separated by aliphatic or aromatic...

Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase.

Mazumder, A, Pommier, Y

We have examined the activities of HIV-1 integrase on substrates containing mismatches, composed of deoxyuridine at different positions in either the processed or nonprocessed strand of viral DNA,...

Incorporation of a fluorescent guanosine analog into oligonucleotides and its application to a real time assay for the HIV-1 integrase 3'-processing reaction.

Hawkins, M E, Pfleiderer, W, Mazumder, A, Pommier, Y G, Balis, F M

We have synthesized a highly fluorescent (quantum yield 0.88) guanosine analog, (3-methyl-8-(2-deoxy-beta-D-ribofuranosyl) isoxanthopterin (3-Mi) in a dimethoxytrityl, phosphoramidite protected form,...

Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that...

Methylphosphonodiester substitution near the conserved CA dinucleotide in the HIV LTR alters both extent of 3'-processing and choice of nucleophile by HIV-1 integrase.

Mazumder, A, Gupta, M, Pommier, Y

We present evidence suggesting that the 3'-processing activity of HIV-1 integrase is dramatically affected by electrostatic and/or steric perturbations 3' to the conserved CA dinucleotide. When the...

Probing the active site residues in aromatic donor oxidation in horseradish peroxidase: involvement of an arginine and a tyrosine residue in aromatic donor binding.

Adak, S, Mazumder, A, Banerjee, R K

The plausible role of arginine and tyrosine residues at the active side of horseradish peroxidase (HRP) in aromatic donor (guaiacol) oxidation was probed by chemical modification followed by...

Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells

Grimm, EA, Ramsey, KM, Mazumder, A, Wilson, DJ, Djeu, JY, Rosenberg, SA

Culture of human peripheral blood lymphocytes (PBL) in partially purified and lectin-free interleukin 2 results in the generation of cytotoxic effector cells which have the unique property of lysing...