A. Mencarelli

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.

Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...

Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...

Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.

Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...

The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...

Expression pattern of the RAR alpha-PML fusion gene in acute promyelocytic leukemia.

Alcalay, M, Zangrilli, D, Fagioli, M, Pandolfi, P P, Mencarelli, A, Lo Coco, F, ...

Two chimeric genes, PML-RAR alpha and RAR alpha-PML, are formed as a consequence of the acute promyelocytic leukemia (APL)-specific reciprocal translocation of chromosomes 15 and 17 [t(15;17)]....

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

Alcalay, M, Zangrilli, D, Pandolfi, P P, Longo, L, Mencarelli, A, Giacomucci, A, ...

Acute promyelocytic leukemias (APLs) are characterized by a reciprocal balanced translocation that involves chromosomes 15 and 17 [t(15;17)]. We report the isolation and characterization of one of...

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.

Pandolfi, P P, Alcalay, M, Fagioli, M, Zangrilli, D, Mencarelli, A, Diverio, D, ...

The acute promyelocytic leukaemia (APL) 15;17 translocation generates a PML/RAR alpha chimeric gene which is transcribed as a fusion PML/RAR alpha mRNA. Molecular studies on a large series of APLs...

Heterogeneous nuclear expression of the promyelocytic leukemia (PML) protein in normal and neoplastic human tissues.

Gambacorta, M., Flenghi, L., Fagioli, M., Pileri, S., Leoncini, L., Bigerna, B., ...

The RING-finger promyelocytic leukemia (PML) protein is the product of the PML gene that fuses with the retinoic acid receptor-alpha gene in the t(15; 17) translocation of acute promyelocytic...

Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis

Fiorucci, S, Orlandi, S, Mencarelli, A, Caliendo, G, Santagada, V, Distrutti, E, ...