MacKay, K., Milicic, A., Lee, D., Tikly, M., Laval, S., Shatford, J., ...
Introduction. IL-10 is an immunoregulatory cytokine which may modulate disease expression in rheumatoid arthritis (RA). The IL-10 gene is highly polymorphic with a number of single nucleotide...
Non-inherited maternal HLA alleles are associated with rheumatoid arthritis (2003)
Harney, S., Newton, J., Milicic, A., Brown, M. A., Wordsworth, B. P.
Background. Rheumatoid arthritis (RA) is strongly associated with a series of HLA-DRB1 alleles that encode a conserved sequence of amino acids (70Q/R K/R R A A74) in the DRβ1 chain, known as the...
Non-inherited maternal HLA alleles are associated with rheumatoid arthritis (2003)
Harney, S, Newton, J, Milicic, A, Brown, MA, Wordsworth, BP
Background. Rheumatoid arthritis (RA) is strongly associated with a series of HLA-DRB1 alleles that encode a conserved sequence of amino acids ((70)Q/R K/R RAA(74)) in the DRbeta1 chain, known as the...
Newton, J, Brown, MA, Milicic, A, Ackerman, H, Darke, C, Wilson, JN, ...
Objective. HLA-DRB1, a major genetic determinant of susceptibility to rheumatoid arthritis (RA), is located within 1,000 kb of the gene encoding tumor necrosis factor (TNF). Because certain...
HLA-DR/DQ haplotype in rheumatoid arthritis: Novel allelic associations in UK Caucasians (2002)
Milicic, A, Lee, D, Brown, MA, Darke, C, Wordsworth, BP
Objective. To elucidate the relative importance of the HLA-DR and HLA-DQ loci in conferring genetic predisposition to rheumatoid arthritis (RA). Methods. HLA-DRB1 and HLA-DQB1 alleles were typed in a...
MacKay, K, Eyre, S, Myerscough, A, Milicic, A, Barton, A, Laval, S, ...
Objective. To undertake a systematic wholegenome screen to identify regions exhibiting genetic linkage to rheumatoid arthritis (RA). Methods. Two hundred fifty-two RA-affected sibling pairs from 182...
Milicic, A, Misra, R, Agrawal, S, Aggarwal, A, Brown, MA, Wordsworth, BP
Objectives: To investigate the association of the FcgammaRIIIA gene with rheumatoid arthritis (RA) in two genetically distinct groups: a white group from the United Kingdom and a northern Indian...
S. H. Laval, A. Timms, S. Edwards, L. Bradbury, S. Brophy, A. Milicic, ...
This paper remains the largest genomewide linkage study in AS, and provides a road map of the location of genes involved in the disease. Its findings lead to the identification of IL-1 genes involved...
Disparate associations of the FcgammaRIIIa 158/V variant with RA in two diverse populations (2001)
Milicic, A, Misra, R, Brown, MA, Wordsworth, BP
No abstract available.
Laval, SH, Timms, A, Edwards, S, Bradbury, L, Brophy, S, Milicic, A, ...
Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved,...
Milicic, A, Brown, MA, Wordsworth, BP
The role of the CTLA-4 antigen in the development of autoimmune diseases is well documented, with several autoimmune disorders showing association or linkage with the CTLA-4 locus. Its role in the...
S. H. Laval, A. Timms, S. Edwards, L. Bradbury, S. Brophy, A. Milicic, ...
This paper remains the largest genomewide linkage study in AS, and provides a road map of the location of genes involved in the disease. Its findings lead to the identification of IL-1 genes involved...
Whole-Genome Screening in Ankylosing Spondylitis: Evidence of Non-MHC Genetic-Susceptibility Loci
Laval, S. H., Timms, A., Edwards, S., Bradbury, L., Brophy, S., Milicic, A., ...
Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved,...
Frater, A. J., Edwards, C. T. T., McCarthy, N., Fox, J., Brown, H., Milicic, A., ...
Human immunodeficiency virus type 1 (HIV-1) genetic diversity is a major obstacle for the design of a successful vaccine. Certain viral polymorphisms encode human leukocyte antigen (HLA)-associated...
Whole-Genome Screening in Ankylosing Spondylitis: Evidence of Non-MHC Genetic-Susceptibility Loci
Laval, S. H., Timms, A., Edwards, S., Bradbury, L., Brophy, S., Milicic, A., ...
Ankylosing spondylitis (AS) is a common inflammatory arthritis predominantly affecting the axial skeleton. Susceptibility to the disease is thought to be oligogenic. To identify the genes involved,...
Frater, A. J., Edwards, C. T. T., McCarthy, N., Fox, J., Brown, H., Milicic, A., ...
Human immunodeficiency virus type 1 (HIV-1) genetic diversity is a major obstacle for the design of a successful vaccine. Certain viral polymorphisms encode human leukocyte antigen (HLA)-associated...
Milicic, A, Misra, R, Agrawal, S, Aggarwal, A, Brown, M, Wordsworth, B
Methods: The distributions of the two alleles of the FcγRIIIA F158V polymorphism were determined in 398 white patients from the United Kingdom and 63 Indian patients with RA and compared with those...