Scientific Commons: A. Rinzema

Contents (2008)

Prof Dr, W. J. Briels, A. Rinzema, Prof Dr, D. J. Tildesly, ...

Numerical modeling and Experimental validation ter verkrijging van de graad van Doctor op gezag van de rector magnificus van Wageningen Universiteit, prof. dr. ir. L. Speelman

Polylactide microspheres prepared by premix membrane emulsification - Effects of solvent removal rate (2008)

Sawalha, H.I.M., Purwanti, N, Rinzema, A., Boom, R.M.

Polylactide microspheres were prepared by pre-mix membrane emulsification and subsequent extraction of solvent in a coagulation bath, and ultimately to the gas phase. The polymer was dissolved in...

Polylactide microspheres prepared by premix membrane emulsification - Effects of solvent removal rate (2008)

Sawalha, H.I.M., Purwanti, N, Rinzema, A., Boom, R.M.

Polylactide microspheres were prepared by pre-mix membrane emulsification and subsequent extraction of solvent in a coagulation bath, and ultimately to the gas phase. The polymer was dissolved in...

Microbiology of synthesis gas fermentation for biofuel production (2007)

Henstra, A.M., Sipma, J., Rinzema, A., Stams, A.J.M.

A significant portion of biomass sources like straw and wood is poorly degradable and cannot be converted to biofuels by microorganisms. The gasification of this waste material to produce synthesis...

A two-phase kinetic model for fungal growth in solid-state cultivation (2007)

Hamidi-Esfahani, Z., Hejazi, P., Abbas Shojaosadati, S., Hoogschagen, M.J., Vasheghani-Farahani, E., Rinzema, A.

A new two-phase kinetic model including exponential and logistic models was applied to simulate the growth rate of fungi at various temperatures. The model parameters, expressed as a function of...

Transport phenomena in fungal colonisation on a food matrix (2007)

Rahardjo, Y.S.P., Rinzema, A.

Modeling conversion and transport phenomena in solid-state fermentation: a review and perspectives (2006)

Rahardjo, Y.S.P., Tramper, J., Rinzema, A.

Solid-state fermentation (SSF) is accompanied inevitably by development of concentration and temperature gradients within the substrate particles and microbial biofilms. These gradients are needed...

Effect of low oxygen concentrations on growth and alpha-amylase production of Aspergillus oryzae in model solid-state fermentation systems (2005)

Rahardjo, Y.S.P., Sie, S., Weber, F.J., Tramper, J., Rinzema, A.

Oxygen transfer in the fungal mat is a major concern in solid-state fermentation (SSF). Oxygen supply into the mycelial layers is hampered by diffusion limitation. For aerobic fungi, like Aspergillus...

Aerial mycelia of Aspergillus oryzae accelerate alpha-amalyse production in a model solid-state fermentation system (2005)

Rahardjo, Y.S.P., Weber, F.J., Haemers, S., Tramper, J., Rinzema, A.

Aspergillus oryzae is commonly used in solid-state fermentation (SSF) and forms abundant aerial mycelia. Previously, we have shown that aerial mycelia are extremely important for the respiration of...

Models for mould growth and process design in solid-state fermentation (2005)

Rinzema, A.

Significance of bed porosity, bran and specific surface area in solid-state cultivation of Aspergillus oryzae (2005)

Rahardjo, Y.S.P., Jolink, F., Haemers, S., Tramper, J., Rinzema, A.

In this paper, the effects of bed porosity, bran and specific surface area on the oxygen uptake rate and ¿-amylase production during growth of Aspergillus oryzae on wheat grain and wheat¿flour...

Fluidized-bed and packed-bed characteristics of gel beads (2005)

Tramper, J., Rinzema, A., Beeftink, H.H.

A liquid-fluidized bed or packed bed with gel beads is attractive as an immobilized-cell bioreactor. The performance of such bioreactors is influenced by the physical behavior of these beads. Three...

Conidial quality of the biocontrol agent Coniothyrium minitans produced by solid-state cultivation in a packed-bed reactor (2004)

Jones, E.E., Weber, F.J., Oostra, J., Rinzema, A., Mead, A., Whipps, J.M.

Conidial germination and novel sand- and soil-based sclerotial parasitism assays were used to test the quality of conidial inoculum of the biocontrol agent Coniothyrium minitans IVT1 produced in...

Polyol accumulation by Aspergillus oryzae at low water activity in solid-state fermentation (2004)

Ruijter, G.J.G., Visser, J., Rinzema, A.

Polyol accumulation and metabolism were examined in Aspergillus oryzae cultured on whole wheat grains or on wheat dough as a model for solid-state culture. In solid-state fermentation (SSF), water...

Modelling of simultaneous effect of moisture and temperature on A. niger growth in solid-state fermentation (2004)

Hamidi-Esfahani, Z., Shojaosadati, S.A., Rinzema, A.

In the present work a two factorial design of experiments was applied to study the simultaneous effect of temperature and moisture on A. niger growth in the solid-state fermentation (SSF). The...

Combined discrete particle and continuum model predicting solid-state fermentation in a drum fermentor (2004)

Schutyser, M.A.I., Briels, W.J., Boom, R.M., Rinzema, A.

The development of mathematical models facilitates industrial (large-scale) application of solid-state fermentation (SSF). In this study, a two-phase model of a drum fermentor is developed that...

Chinese vinegar and its solid-state fermentation process (2004)

Beeftink, H.H., Ooijkaas, L.P., Rinzema, A., ...

Recent developments in inoculum production, application and pathogenicity in the biocontrol agent Coniothyrium minitans (2004)

Whipps, J.M., Bennett, A.B., Challen, M., Hill, R., Jones, E.E., ...

Limitations of membrane cultures as a model solid-state fermentation system (2004)

Rahardjo, Y.S.P., Korona, D., Haemers, S., Weber, F.J., Tramper, J., Rinzema, A.

Aims: To examine the reliability of membrane cultures as a model solid-state fermentation (SSF) system. Methods and Results: In overcultures of Aspergillus oryzae on sterilized wheat flour discs...

Combined discrete particle and continuum model predicting solid-state fermentation in a drum fermentor (2004)

Schutyser, M.A.I., Briels, W.J., Boom, R.M., Rinzema, A.

Combined discrete particle and continuum model predicting solid-state fermentation in a drum fermentor (2004)

Schutyser, M.A.I., Briels, W.J., Boom, R.M., Rinzema, A.

The development of mathematical models facilitates industrial (large-scale) application of solid-state fermentation (SSF). In this study, a two-phase model of a drum fermentor is developed that...

Heat and water transfer in a rotating drum containing solid substrate particles (2003)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Rinzema, A., Boom, R.M.

In previous work we reported on the simulation of mixing behavior of a slowly rotating drum for solid-state fermentation (SSF) using a discrete particle model. In this investigation the discrete...

Substrate aggregation due to aerial hyphae during discontinously mixed solid-state fermentation with aspergillus oryzae: experiments and modeling (2003)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

Solid-state fermentation (SSF) is prone to process failure due to channeling caused by evaporative cooling and the formation of an interparticle mycelium network. Mixing is needed to break the...

Numerical simulation and PEPT measurements of a 3D conical helical-blade mixer: a high potential solids mixer for solid-state fermentation (2003)

Schutyser, M.A.I., Briels, W.J., Rinzema, A., Boom, R.M.

Biochemical engineering of solid-state fermentation (2003)

Weber, F.J., Oostra, J., Nagel, F.J.I., Schutyser, M.A.I., Hoogschagen, M.J., Rahardjo, Y.S.P., ...

Substrate aggregation due to aerial hyphae during discontinuously mixed solid-state fermentation with Aspergillus oryzae: Experiments and modeling (2003)

Schutyser, M.A.I., Pagter, P. De, Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

Numerical simulation and PEPT measurements of a 3D conical helical-bla de mixer: A high potential solids mixer for solid-state fermentation (2003)

Schutyser, M.A.I., Briels, W.J., Rinzema, A., Boom, R.M.

Substrate aggregation due to aerial hyphae during discontinuously mixed solid-state fermentation with Aspergillus oryzae: Experiments and modeling (2003)

Schutyser, M.A.I., Pagter De, P., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

Solid-state fermentation (SSF) is prone to process failure due to channeling caused by evaporative cooling and the formation of an interparticle mycelium network. Mixing is needed to break the...

Numerical simulation and PEPT measurements of a 3D conical helical-blade mixer: A high potential solids mixer for solid-state fermentation (2003)

Schutyser, M.A.I., Briels, W.J., Rinzema, A., Boom, R.M.

Helical-blade solids mixers have a large potential as bioreactors for solid-state fermentation (SSF). Fundamental knowledge of the flow and mixing behavior is required for robust operation of these...

Heat and water transfer in a rotating drum containing solid substrate particles (2003)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Rinzema, A., Boom, R.M.

In previous work we reported on the simulation of mixing behavior of a slowly rotating drum for solid-state fermentation (SSF) using a discrete particle model. In this investigation the discrete...

Validation of a model for process development and scale-up of packed-bed solid-state bioreactors (2002)

Weber, F.J., Oostra, J., Tramper, J., Rinzema, A.

We have validated our previously described model for scale-up of packed-bed solid-state fermenters (Weber et al., 1999) with experiments in an adiabatic 15-dm3 packed-bed reactor, using the fungi...

Three-dimensional simulation of grain mixing in three different rotating drum designs for solid-state fermentation (2002)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

A previously published two-dimensional discrete particle simulation model for radial mixing behavior of various slowly rotating drums for solid-state fermentation (SSF) has been extended to a...

Distinct element modelling of rotating solid-state fermenters (2002)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

Water and glucose gradients in the substrate measured with NMR imaging during solid-state fermentation with Aspergillus oryzae (2002)

Nagel, F.J., Tramper, J., Rinzema, A.

Gradients inside substrate particles cannot be prevented in solid-state fermentation. These gradients can have a strong effect on the physiology of the microorganisms but have hitherto received...

Contribution of aerial hyphae of Aspergillus oryzae to respiration in a model solid-state fermentation system (2002)

Rahardjo, Y.S.P., Weber, F.J., Tramper, J., Rinzema, A.

Aspergillus oryzae in solid-state and submerged fermentations progress report on a multi-disciplinary project (2002)

Ruijter, G., Rahardjo, Y.S.P., Hoogschagen, M.J., Heerikhuisen, M., Levin, A., ...

We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus...

Aspergillus oryzae in solid-state and submerged fermentations. Progres report on a multi-disciplinary project (2002)

Ruijter, G., Rahardjo, Y.S.P., Hoogschagen, M.J., Heerikhuisen, M., Levin, A., ...

We report the progress of a multi-disciplinary research project on solid-state fermentation (SSF) of the filamentous fungus Aspergillus oryzae. The molecular and physiological aspects of the fungus...

Contribution of aerial hyphae of Aspergillus oryzae to respiration in a model solid-state fermentation system (2002)

Rahardjo, Y.S., Weber, F.J., Comte, E.P. Le, Tramper, J., Rinzema, A.

Three-dimensional simulation of grain mixing in three different rotating drum designs for solid-state fermentation (2002)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Rinzema, A.

Three-dimensional simulation of grain mixing in three different rotating drum designs for solid-state fermentation (2002)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

A previously published two-dimensional discrete particle simulation model for radial mixing behavior of various slowly rotating drums for solid-state fermentation (SSF) has been extended to a...

Temperature control in a continuously mixed bioreactor for solid-state fermentation (2001)

Tramper, J., Bakker, M.S.N., Rinzema, A.

A continuously mixed, aseptic paddle mixer was used successfully for solid-state fermentation (SSF) with Aspergillus oryzae on whole wheat kernels. Continuous mixing improved temperature control and...

Model for on-line moisture-content control during solid-state fermentation (2001)

Tramper, J., Bakker, M.S.N., Rinzema, A.

In this study we describe a model that estimates the extracellular (nonfungal) and overall water contents of wheat grains during solid-state fermentation (SSF) with Aspergillus oryzae, using on-line...

Influence of wheat type ad pretreatment on fungal growth in solid-state fermentation (2001)

Hoogschagen, M., Zhu, Y., Tramper, J., Rinzema, A.

The respiration kinetics of Aspergillus oryzae on different varieties of whole wheat kernels were studied. Six wheat varieties were pretreated in two different ways. Five of the six substrates...

Intra-particle oxygen diffusion limitation in solid-state fermentation (2001)

Oostra, J., Tramper, J., Rinzema, A.

Oxygen limitation in solid-state fermentation (SSF) has been the topic of modeling studies, but thus far, there has been no experimental elucidation on oxygen-transfer limitation at the particle...

Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter (2001)

Schutyser, M.A.I., Padding, J.T., Weber, F.J., Briels, W.J., Rinzema, A., Boom, R.

A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and...

Design of liquid-liquid-solid fluidised-bed bioreactors (2001)

Rinzema, A., Tramper, J.

Influence of wheat type and pretreatment on fungal growth in solid-state fermentation (2001)

Hoogschagen, M., Zhu, Y., Tramper, J., Rinzema, A.

The fungal biocontrol agent Coniothyrium minitans: production by solid-state fermentation, application and marketing (2001)

Antoine, N., Buitelaar, R.M., Oostra, J., Rinzema, A., Weber, F.J.

Biological control agents (BCAs) are potential alternatives for the chemical fungicides presently used in agriculture to fight plant diseases. Coniothyrium minitans is an example of a promising...

Ontwikkeling van een simulatiemodel voor onderzoek, Vastestoffermentatie (2001)

Schutyser, M.A.I., Weber, F.J., Briels, W., Rinzema, A., Boom, R.M.

Voor de productie van verschillende enzymen en secundaire metabolieten kan SSF beter zijn dan de conventionele vloeistoffermentatie. Met de nieuwe simulatiemehode tracht men meer inzicht te krijgen...

Rational design of mixed solid-state fermenters (2001)

Schutyser, M.A.I., Weber, F.J., Briels, W.J., Boom, R.M., Rinzema, A.

Biochemical engineering of solid-state fermentations (2001)

Rinzema, A., Weber, F.J., Nagel, F.J.I., Oostra, J., Schutyser, M.A.I., Hoogschagen, M.J., ...

The fungal biocontrol agent Coniothyrium minitans: production by solid-state fermentation, application and marketing (2001)

De Vrije, T., Antoine, N., Buitelaar, R.M., Bruckner, S., Dissevelt, M., Durand, A., ...

Intra-particle oxygen diffusion limitation in solid-state fermentation (2001)

Oostra, J., Comte, E.P. Le, Tramper, J., Rinzema, A.

Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter (2001)

Schutyser, M.A.I., Padding, J.T., Weber, F.J., Briels, W.J., Rinzema, A., Boom, R.

Discrete particle simulations predicting mixing behavior of solid substrate particles in a rotating drum fermenter (2001)

Schutyser, M.A.I., Padding, J.T., Weber, F.J., Briels, W.J., Rinzema, A., Boom, R.

A soft-sphere discrete particle model was used to simulate mixing behavior of solid substrate particles in a slow rotating drum for solid-state fermentation. In this approach, forces acting on and...

Modelling growth of Aspergillus oryzae in relation to temperature in a packed-bed solid-state fermentation (2000)

Hoogschagen, M., Weber, F.J., Rinzema, A., Zhu, Y., Tramper, J.

Defined media and inert supports : their potential as solid-state fermentation production systems (2000)

Ooijkaas, L.P., Weber, F.J., Buitelaar, R.M., Tramper, J., Rinzema, A.

Growth and sporulation stoichiometry and kinetics of coniothyrium minitans on agar media (2000)

Ooijkaas, L.P., Buitelaar, R.M., Tramper, J., Rinzema, A.

Coniothyrium minitans was cultivated on agar media with different concentrations of starch, urea, and trace elements. By means of elemental balances, the stoichiometry of growth and sporulation was...

Solid-state cultivation of the biocontrol fungus Coniothyrium minitans in mixed and non-mixed systems : the step from laboratory to pilot-scale reactors (2000)

Oostra, J., Weber, F.J., Rinzema, A., Tramper, J.

Model-based bioreactor selection for large-scale solid-state cultivation of Coniothyrium minitans spores on oats (2000)

Oostra, J., Tramper, J., Rinzema, A.

Modelling fungal solid-state fermentation at the particle-level (2000)

Rahardjo, Y.S.P., Weber, F.J., Le Comte, E.P., Rinzema, A.

Biochemical engineering of solid-state fermentations (2000)

Rinzema, A., Weber, F.J., Nagel, F.J.I., Oostra, J., Schutyser, M.A.I., Hoogschagen, M., ...

Granular dynamics in mixed solid-state fermentors (2000)

Schutyser, M., Weber, F., Briels, W., Boom, R.M., Rinzema, A.

Measurement of density, particle size and shape of support (2000)

Tramper, J., Rinzema, A.

Liquid fluidization of gel-bead particles (2000)

Tramper, J., Rinzema, A.

Solid-state fermentation in a packed-bed bioreactor (2000)

Weber, F., Oostra, J., Tramper, J., Rinzema, A.

Effect of the availability of magnesium ions in K-carrageenan gels on the formation of conidia by Coniothyrium minitans (2000)

Weber, F.J., Tramper, J., Rinzema, A.

Growth and sporulation stoichiometry and kinetics of Coniothyrium minitans on agar media (2000)

Ooijkaas, L.P., Buitelaar, R.M., Tramper, J., Rinzema, A.

Improved model system for solid-substrate fermentation : effects of pH, nutrients and buffer on fungal growth rate (1999)

Nagel, F.J., Oostra, J., Tramper, J., Rinzema, A.

Mixed fermenters for solid-state cultivation of Coniothyrium minitans for biological pest control (1999)

Rinzema, A., Timmer, H., Sijtsma, L., Tramper, J., Oostra, J.

Intra-particle oxygen diffusion limitation in solid-state fermentation (1999)

Rinzema, A., Oostra, J., Le Comte, E.P., Tramper, J.

Modelling fungal solid-state fermentation: the role of inactivation kinetics (1999)

Smits, J.P., Tramper, J., Knol, W.C., Geelhoed, W., Peeters, M., ...

Quantitative recovery of fungal biomass grown on solid k-carrageenan media (1999)

Weber, F.J., Tramper, J., Rinzema, A.

A simplified approach for process development and scale-up of solid-state cultivation in a packed-bed reactor (1999)

Weber, F., Tramper, J., Rinzema, A.

A simplified material and energy balance approach for process development and scale-up of Coniothyrium minitans conidia production by solid-state cultivation in a packed-bed reactor (1999)

Weber, F.J., Tramper, J., Rinzema, A.

Transglutaminase as a potential tool in developing novel protein foods (1999)

Zhu, Y., Bol, J., Rinzema, A., Tramper, J., Wijngaards, G.

Modelling fungal solid-state fermentation: the role of inactivation kinetics (1999)

Smits, JP, Van Sonsbeek, HM, Tramper, J, Knol, W, Geelhoed, W, Peeters, M, ...

The theoretical mathematical models described in this paper are used to evaluate the effects of fungal biomass inactivation kinetics on a non-isothermal tray solid-state fermentation (SSF). The...

Solid-state fermentation: a mini review. (1998)

Smits, J.P., Sonsbeek, H.M., Rinzema, A., Tramper, J.

Fed-batch fermentation dealing wit nitrogen limitation in microbial transglutaminase production by Streptoverticillium mobaraense. (1998)

Zhu, Y., Rinzema, A., Tramper, J., Bol, J.

Microbial transglutaminase production by Streptoverticillium mobaraense: analysis of amino acid metabolism using mass balances. (1998)

Zhu, Y., Rinzema, A., Bonarius, H.P.J., Tramper, J., Bol, J.

Culture medium design based on stoichiometric analysis of cell lines and products. (1998)

Zhu, Y., Rinzema, A., Tramper, J., Bol, J.

The influence of temperature on kinetics in solid-state fermentation (1998)

Smits, J.P., Rinzema, A., Tramper, J., Sonsbeek, H.M., Hage, J.C., Kaynak, A., ...

20 Biomass and productivity estimates in solid substrate fermentations. (1997)

Nout, M.J.R., Rinzema, A., Smits, J.P.