A. Skoultchi

An integrated approach for identifying and mapping human genes.

Das Gupta, R, Morrow, B, Marondel, I, Parimoo, S, Goei, V L, Gruen, J, ...

We have developed a method for generating expressed-sequence maps of human chromosomes. The method involves several steps that begin with libraries of highly representative short cDNAs prepared by...

A dominant positive and negative selectable gene for use in mammalian cells.

Schwartz, F, Maeda, N, Smithies, O, Hickey, R, Edelmann, W, Skoultchi, A, ...

We have constructed three different fusion genes containing the herpes simplex virus thymidine kinase (HSV tk) and the bacterial neomycin phosphotransferase (neo) genes. All three fusion genes...

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N, Warrick, H, DeRiel, J K, Tuan, D, Forget, B G, Skoultchi, A, ...

We have attempted to introduce some eukaryotic and prokaryotic DNA sequences into mouse fibroblasts. Purified herpes thymidine kinase gene (tk) was introduced into mouse cells. The presence of the...

Regulation of a human cardiac actin gene introduced into rat L6 myoblasts suggests a defect in their myogenic program.

Hickey, R, Skoultchi, A, Gunning, P, Kedes, L

The rat myogenic cell line L6E9 induces skeletal but not cardiac alpha-actin mRNA upon fusion to form myotubes. However, when a human cardiac alpha-actin gene was introduced into L6E9 myoblasts,...

Effect of interferon on dimethyl sulfoxide-stimulated Friend erythroleukemic cells: ultrastructural and biochemical study.

Luftig, R B, Conscience, J F, Skoultchi, A, McMillan, P, Revel, M, Ruddle, F H

Treatment of dimethyl sulfoxide-stimulated Friend erythroleukemic cells (clone 745) with mouse interferon (50 U/ml) led to the following changes: (i) a net decrease (40 to 60%) in both the total...

An integrated approach for identifying and mapping human genes.

Das Gupta, R, Morrow, B, Marondel, I, Parimoo, S, Goei, V L, Gruen, J, ...

We have developed a method for generating expressed-sequence maps of human chromosomes. The method involves several steps that begin with libraries of highly representative short cDNAs prepared by...

A dominant positive and negative selectable gene for use in mammalian cells.

Schwartz, F, Maeda, N, Smithies, O, Hickey, R, Edelmann, W, Skoultchi, A, ...

We have constructed three different fusion genes containing the herpes simplex virus thymidine kinase (HSV tk) and the bacterial neomycin phosphotransferase (neo) genes. All three fusion genes...

Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells.

Hsiung, N, Warrick, H, DeRiel, J K, Tuan, D, Forget, B G, Skoultchi, A, ...

We have attempted to introduce some eukaryotic and prokaryotic DNA sequences into mouse fibroblasts. Purified herpes thymidine kinase gene (tk) was introduced into mouse cells. The presence of the...

Regulation of a human cardiac actin gene introduced into rat L6 myoblasts suggests a defect in their myogenic program.

Hickey, R, Skoultchi, A, Gunning, P, Kedes, L

The rat myogenic cell line L6E9 induces skeletal but not cardiac alpha-actin mRNA upon fusion to form myotubes. However, when a human cardiac alpha-actin gene was introduced into L6E9 myoblasts,...

Effect of interferon on dimethyl sulfoxide-stimulated Friend erythroleukemic cells: ultrastructural and biochemical study.

Luftig, R B, Conscience, J F, Skoultchi, A, McMillan, P, Revel, M, Ruddle, F H

Treatment of dimethyl sulfoxide-stimulated Friend erythroleukemic cells (clone 745) with mouse interferon (50 U/ml) led to the following changes: (i) a net decrease (40 to 60%) in both the total...