Wright, A., Zignol, M., Van Deun, A., Falzon, D., Ruesch Gerdes, S., Feldman, K., ...
BACKGROUND: The Global Project on Anti-Tuberculosis Drug Resistance has been gathering data since 1994. This study provides the latest data on the extent of drug resistance worldwide. METHODS: Data...
Noeske, J., Dopico, E., Torrea, G., Wang, H., Van Deun, A.
SETTING: A busy urban hospital in Cameroon. OBJECTIVES: To compare the yield in bacteriologically proven tuberculosis (TB) cases examining two morning vs. three spot-morning-spot sputum specimens (MM...
Bulk acid-fast staining of sputum smears: time to end a taboo (2009)
Kam, K. M., Yip, C. W., Tang, H. S., Van Deun, A.
SETTING: A high-throughput laboratory routinely performing fluorescence microscopy for acid-fast bacilli (AFB) smear with automated bulk staining. OBJECTIVES: To determine the risk of false-positive...
Van Rie, A., Fitzgerald, D., Kabuya, G., Van Deun, A., Tabala, M., Jarret, N., ...
Sputum smear microscopy is the main and often only laboratory technique used for the diagnosis of tuberculosis in resource-poor countries, making quality assurance (QA) of smear microscopy an...
Van Deun, A., Chuquiyauri, R., Torrea, G., Agapito, J., Verdonck, K., Gotuzzo, E.
The aim of this study was to determine the usefulness of fluorescence microscopy (FM) at a referral centre in a middle-income country. Direct Ziehl-Neelsen (ZN) and direct, as well as concentrated,...
Torrea, G., Chakaya, J., Mayabi, M., Van Deun, A.
SETTING: Three busy laboratories in Nairobi, Kenya. OBJECTIVES: To determine the performance of an affordable fluorescence system (FluoreslenS) for tuberculosis microscopy, and to test an...
Eyangoh, S. I., Torrea, G., Tejiokem, M. C., Kamdem, Y., Piam, F. F., Noeske, J., ...
Bleach sputum concentration and fluorescence microscopy (FM) are reportedly more sensitive than direct Ziehl-Neelsen (ZN) sputum smears for tuberculosis detection, and might be particularly valuable...
Van Deun, A., Chonde, T. M., Gumusboga, M., Rienthong, S.
SETTING: Tuberculosis (TB) reference laboratory in Bangkok, Thailand, and two health centres in Dar es Salaam, Tanzania. OBJECTIVES: To assess the performance and user-friendliness of a...
Implementation of a national anti-tuberculosis drug resistance survey in Tanzania (2008)
Chonde, T. M., Doulla, B., Van Leth, F., Mfinanga, S. G. M., Range, N., Lwilla, F., ...
BACKGROUND: A drug resistance survey is an essential public health management tool for evaluating and improving the performance of National Tuberculosis control programmes. The current manuscript...
Improving sputum microscopy services for the diagnosis of tuberculosis in Peru and Bolivia (2007)
SIDDIQI, K, NEWELL, JN, Van Der Stuyft, Patrick, GOTUZZO, E, TORRICO, F, VAN DEUN, A, ...
Improving sputum microscopy services for the diagnosis of tuberculosis in Peru and Bolivia (2007)
Siddiqi, K., Newell, J. N., Gotuzzo, E., Torrico, F., Van Deun, A., ...
SETTING: Sixteen primary care health centres in Peru and Bolivia. OBJECTIVES: To assess the utilisation of microscopy services in Peru and Bolivia and determine if clinical audit, a quality...
Gilpin, C., Kim, S. J., Lumb, R., Rieder, H. L., Van Deun, A.
This report is the consensus-based, agreed position of the participants in a workshop for experts in sputum smear microscopy organised in August 2005 by the International Union Against Tuberculosis...
Rigouts, L., Nolasco, O., De Rijk, P., Nduwamahoro, E., Van Deun, A., Ramsay, A., ...
New rpoB gene primers for detecting Rif(r) in Mycobacterium tuberculosis complex bacteria achieved 100% specificity and 88% (fresh sputa) and 92% (ethanol-preserved sputa) diagnostic sensitivity and...
Worldwide emergence of extensively drug-resistant tuberculosis (2007)
Shah, N. S., Wright, A., Bai, G. H., Barrera, L., Boulahbal, F., Mart¡n-Casabona, N., ...
Mycobacterium tuberculosis strains that are resistant to an increasing number of second-line drugs used to treat multidrug-resistant tuberculosis (MDR TB) are becoming a threat to public health...
Shamputa, I. C., Van Deun, A., Salim, M. A. H., Hossain, M. A., Fissette, K., De Rijk, P., ...
The definitive version is available at www3.interscience.wiley.com
Van Deun, A., Zwahlen, M., Bola, V., Lebeke, R., Bahati, E., Lubamba, P., ...
SETTING: Kinshasa Province, Democratic Republic of Congo. OBJECTIVE: To identify and validate register-based indicators of acid-fast bacilli (AFB) microscopy quality. DESIGN: Selection of...
Not all microscopes are equal (2006)
Lumb, R., Van Deun, A., Kelly, P. M., Bastian, Ivan
Copyright © 2006 The Union
Not all microscopes are equal (2006)
Lumb, R., Van Deun, A., Kelly, P. M., Bastian, Ivan
Copyright © 2006 The Union
Abdel Aziz, M., Wright, A., Laszlo, A., De Muynck, A., Portaels, F., Van Deun, A., ...
BACKGROUND: The burden of tuberculosis is compounded by drug-resistant forms of the disease. This study aimed to analyse data on antituberculosis drug resistance gathered by the WHO and International...
Early and rapid microscopy-based diagnosis of true treatment failure and MDR-TB (2006)
Hamid Salim, A., Aung, K. J. M., Hossain, M. A., Van Deun, A.
SETTING: Damien Foundation tuberculosis (TB) control project in Bangladesh. OBJECTIVE: Early diagnosis of true TB treatment failure and multidrug resistance (MDR) for more efficient DOTS-Plus....
Sanders, M., Van Deun, A., Ntakirutimana, D., Masabo, J. P., Rukundo, J., Rigouts, L., ...
SETTING: Bujumbura, Burundi. OBJECTIVES: To determine resistance levels of Mycobacterium tuberculosis (TB) to the main anti-tuberculosis drugs after 11 years of a DOTS programme using a...
Traore, H., Van Deun, A., Shamputa, I. C., Rigouts, L., Portaels, F.
The INNO-LiPA.Rif TB test (LiPA) has only been applied to a limited number of clinical specimens. To assess the utility of this test for detecting Mycobacterium tuberculosis complex DNA and rifampin...
Van Deun, A., Aung, K. J. M., Hamid Salim, A., Ali, M. A., Naha, M. S., Das, P. K., ...
SETTING: Damien Foundation tuberculosis (TB) control projects in Bangladesh. OBJECTIVE: To assess the effectiveness of a 1-month extension of the intensive phase for smear-positives at 2 months of an...
Tuberculosis drug resistance in the world (2006)
Portaels, F., Rigouts, L., Shamputa, I. C., Van Deun, A., Abdel Aziz, M.
Van Deun, A., Salim, A. H., Aung, K. J. M., Hossain, M. A., Chambugonj, N., Hye, M. A., ...
SETTING: A field project in Bangladesh. OBJECTIVE: To compare the effectiveness of commonly used carbolfuchsin staining variations. DESIGN: Routine hot Ziehl-Neelsen (ZN) 1% basic fuchsin staining...
Should isoniazid and clofazimine be used to treat multidrug-resistant tuberculosis? [reply] (2005)
Van Deun, A., Salim, A. H., Das, P. K., Bastian, I., Portaels, F.
Kotlowski, R., Shamputa, I. C., El Aila, N. A., Sajduda, A., Rigouts, L., Van Deun, A., ...
In the present study we attempted to develop a PCR-based epidemiological tool for the differentiation of Mycobacterium tuberculosis isolates. Use of the designed primers Mtb1...
Gender differences in tuberculosis: a prevalence survey done in Bangladesh (2004)
Salim, A. H., Declercq, E., Van Deun, A., Saki, K. A. R.
SETTING: Bangladesh national tuberculosis control programme districts supported by the Damien Foundation (population 18 million). OBJECTIVE: To determine whether the observed gender difference is...
Shamputa, I. C., Rigouts, L., Eyongeta, L. A., El Aila, N. A., Van Deun, A., Salim, A. H., ...
Correction: J Clin Microbiol 2005, 43(2), 1015-1016
EQA for AFB smear microscopy manual [reply] (2004)
Van Deun, A., Ridderhof, J., Iademarco, M. F., Humes, R., Becx Bleumink, M., Endo, S., ...
Scanty AFB smears: what's in a name? (2004)
Van Deun, A., Salim, A. H., Cooreman, E., Daru, P., Das, A. P. K., Aung, K. J. M., ...
SETTING: A tuberculosis control project in Bangladesh. OBJECTIVE: To document the frequency and diagnostic value of smears with scanty acid-fast bacilli (AFB) (IUATLD/WHO scale, < 10/100 high power...
Drug resistance monitoring: combined rates may be the best indicator of programme performance (2004)
Van Deun, A., Salim, A. H., Daru, P., Das, A. P. K., Aung, K. J. M., Hossain, M. A., ...
SETTING: Greater Mymensingh District, Bangladesh. OBJECTIVES: To determine changes in prevalence of drug resistance of Mycobacterium tuberculosis under DOTS. DESIGN: Drug susceptibility testing of...
Results of a standardised regimen for multidrug-resistant tuberculosis in Bangladesh (2004)
Van Deun, A., Salim, A. H., Das, P. K., Bastian, I., Portaels, F.
SETTING: Individualised regimens based on drug susceptibility test results, generally used to treat multidrug-resistant tuberculosis (MDR-TB), require often unavailable expertise and resources....
Recurrence in tuberculosis: relapse or reinfection? (2003)
LAMBERT, ML, HASKER, E, VAN DEUN, A, ROBERFROID, D, BOELAERT, M, Van Der Stuyft, Patrick
Rifampin and recurrence of tuberculosis among patients infected with HIV (2003)
LAMBERT, ML, HASKER, E, VAN DEUN, A, ROBERFROID, D, Van Der Stuyft, Patrick
Recurrence in tuberculosis: relapse or reinfection? (2003)
Lambert, M. L., Hasker, E., Van Deun, A., Roberfroid, D., Boelaert, M.
The importance of reinfection as a cause for recurrence of tuberculosis is unclear and has potential public-health implications. We systematically searched published material for studies using DNA...
Mahendradhata, Y., Lambert, M. L., Van Deun, A., Matthys, F., Boelaert, M.
We argue that tuberculosis control cannot reach its proposed global targets without investment in an adequate network of accessible, effective and comprehensive health services. Lessons from the past...
Systematic restaining of sputum smears for quality control is useful in Burundi (2003)
Buzingo, T., Sanders, M., Masabo, J. P., Nyandwi, S., Van Deun, A.
SETTING: Routine tuberculosis control services in Burundi. OBJECTIVE: To determine whether systematic restaining of sputum smears for acid-fast bacilli (AFB) prior to rechecking quality assessment is...
Van Deun, A., Salim, A. H., Cooreman, E., Hossain, A., Rema, A., Chambugonj, N., ...
SETTING: A tuberculosis control project in Bangladesh. OBJECTIVE: To define the efficiency of numbers of microscopic fields screened and the sputum collection scheme used for diagnostic smear...
Van Deun, A., Hamid Salim, A., Rigouts, L., Rahman, M., Fissette, K., Portaels, F.
SETTING: A national tuberculosis control programme (NTP) disposing of baseline drug resistance rates and using 2EHRZ/6TH in the treatment of new cases. OBJECTIVE: To estimate the extent of drug...
Bastian, I., Rigouts, L., Van Deun, A., Portaels, F.
Multidrug-resistant tuberculosis (MDRTB) should be defined as tuberculosis with resistance to at least isoniazid and rifampicin because these drugs are the cornerstone of short-course chemotherapy,...
Van Deun, A., Aung Kya Maug, Cooreman, E., Hossain, M. A., Chambuganj, N., Rema, V., ...
SETTING: A non-governmental organisation (NGO) supported tuberculosis control programme in Bangladesh with good smear microscopy. OBJECTIVE: To verify whether bleach sedimentation method increases...
Van Rie, A., Fitzgerald, D., Kabuya, G., Van Deun, A., Tabala, M., Jarret, N., ...
Sputum smear microscopy is the main and often only laboratory technique used for the diagnosis of tuberculosis in resource-poor countries, making quality assurance (QA) of smear microscopy an...
Bastian, I., Rigouts, L., Van Deun, A., Portaels, F.
Multidrug-resistant tuberculosis (MDRTB) should be defined as tuberculosis with resistance to at least isoniazid and rifampicin because these drugs are the cornerstone of short-course chemotherapy,...