A. Vecchi

Differential recognition and scavenging of native and truncated macrophage-derived chemokine (macrophage-derived chemokine/CC chemokine ligand 22) by the D6 decoy receptor (2004)

Locati, M, Galliera, E, Vulcano, M, Sironi, M, Fra, AM, ...

The promiscuous D6 receptor binds several inflammatory CC chemokines and has been recently proposed to act as a chemokine-scavenging decoy receptor. The present study was designed to better...

Transduction of human MCP-3 by a parvoviral vector induces leukocyte infiltration and reduces growth of human cervical carcinoma cell xenografts (2001)

Grone, HJ, Giese, N, ...

Background The oncosuppressive properties of some autonomous parvoviruses such as H-1 virus, together with their low pathogenicity, make them attractive vectors for tumor-directed gene therapy....

Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages (2000)

Saccani, A, Bottazzi, B, Polentarutti, N, Vecchi, A, ...

IL-12 is a central cytokine in the activation of inflammation and immunity and in the generation of Th1-type responses. Tumor-associated macrophages (TAM) from mouse and human tumors showed defective...

The BeppoSAX 1-8 keV cosmic background spectrum (1999)

Vecchi, A., Molendi, S., Guainazzi, M., Fiore, F., Parmar, A. N.

The spectrum of the 1.0-8.0 keV cosmic X-ray background (CXB) at galactic latitudes > 25 degrees has been measured using the BeppoSAX LECS and MECS instruments. The spectrum is consistent with a...

Il-1 stimulates il-6 production in endothelial cells (1989)

Breviario, F, Proserpio, P, Biondi, A, Vecchi, A, ...

Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors.

Garlanda, C, Parravicini, C, Sironi, M, De Rossi, M, Carozzi, F, ...

A retroviral construct encoding polyoma middle-sized T antigen was used to generate transformed endothelial cell lines from heart (H5V), brain (B9V), and whole-embryo (E10V) of C57BL/6 mice. When...

Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors.

Garlanda, C, Parravicini, C, Sironi, M, De Rossi, M, Carozzi, F, ...

A retroviral construct encoding polyoma middle-sized T antigen was used to generate transformed endothelial cell lines from heart (H5V), brain (B9V), and whole-embryo (E10V) of C57BL/6 mice. When...

Impairment of cytokine production in mice fed a vitamin D3-deficient diet.

Kankova, M, Luini, W, Pedrazzoni, M, Riganti, F, Sironi, M, Bottazzi, B, ...

C57Bl/6 female mice fed a Vitamin D (VIT-D)-deficient diet had serum levels of 25-hydroxyvitamin D decreasing with the time of diet exposure (3 and 8 weeks). Cytokine production (IL-6, TNF and IL-1)...

Natural cytotoxic activity in human lungs.

Bordignon, C, Villa, F, Vecchi, A, Giavazzi, R, Introna, M, Avallone, R, ...

Disease-free surgical lung specimens from 13 patients with neoplastic or infectious diseases and from three subjects with non-neoplastic, non-infectious pathology were mechanically disaggregated....

Activation of K cells in mice with transplanted tumours differing in immunogenicity and metastasizing capacity.

Mantovani, A., Polentarutti, N., Alessandri, G., Vecchi, A., Giuliani, F., Spreafico, F.

The effector arm of antibody-dependent cellular cytotoxicity (ADCC) was evaluated using 51Cr-labelled chicken erythrocytes as targets in BALB/c mice transplanted with the Moloney sarcoma...

Therapeutic effect of interleukin 12 on mouse haemangiosarcomas is not associated with an increased anti-tumour cytotoxic T-lymphocyte activity.

Vizler, C., Rosato, A., Calderazzo, F., Quintieri, L., Fruscella, P., ...

In syngeneic mice, the H5V polyoma middle-T oncogene-transformed endothelioma cell line induces Kaposi's sarcoma-like cavernous haemangiomas that regress transiently, probably because of an...