Aaron Berlin

Closing gaps in the human genome using sequencing by synthesis (2009)

Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, ...

Abstract The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as...

Closing gaps in the human genome using sequencing by synthesis (2009)

Arachchi, Harindra M., Green, Lisa M., Zody, Michael C., Lennon, Niall, Gnerre, Sante, Berlin, Aaron, ...

The most recent release of the finished human genome contains 260 euchromatic gaps (excluding chromosome Y). Recent work has helped explain a large number of these unresolved regions as 'structural'...

AMD3100, a CxCR4 antagonist, attenuates allergic lung inflammation and airway hyperreactivity (2002)

Berlin, Aaron, Skerlj, Renato T, Bridger, Gary J

The role of specific chemokine receptors during allergic asthmatic responses has been relatively undefined. A number of receptors are preferentially expressed on Th2 cells, including CCR4, CCR8, and...

Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome

Belperio, John A., Keane, Michael P., Burdick, Marie D., Lynch, Joseph P., Xue, Ying Ying, Berlin, Aaron, ...

Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival after lung transplantation. Acute rejection, its main risk factor, is characterized by perivascular/bronchiolar leukocyte...

Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome

Belperio, John A., Keane, Michael P., Burdick, Marie D., Lynch, Joseph P., Xue, Ying Ying, Berlin, Aaron, ...

Bronchiolitis obliterans syndrome (BOS) is the major limitation to survival after lung transplantation. Acute rejection, its main risk factor, is characterized by perivascular/bronchiolar leukocyte...

AMD3100, a CxCR4 Antagonist, Attenuates Allergic Lung Inflammation and Airway Hyperreactivity

Lukacs, Nicholas W., Berlin, Aaron, Schols, Dominique, Skerlj, Renato T., Bridger, Gary J.

The role of specific chemokine receptors during allergic asthmatic responses has been relatively undefined. A number of receptors are preferentially expressed on Th2 cells, including CCR4, CCR8, and...

A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity

Ziegelbauer, Karl, Gantner, Florian, Lukacs, Nicholas W, Berlin, Aaron, Fuchikami, Kinji, Niki, Toshiro, ...

Pulmonary inflammatory diseases such as asthma are characterized by chronic, cell-mediated inflammation of the bronchial mucosa.Recruitment and activation of inflammatory cells is orchestrated by a...

Closing gaps in the human genome using sequencing by synthesis

Garber, Manuel, Zody, Michael C, Arachchi, Harindra M, Berlin, Aaron, Gnerre, Sante, Green, Lisa M, ...

A novel method for closing non-structural gaps in the human genome assembly using 454 sequencing is presented here.