Aaron Reinke

Caffeine targets TOR complex I and provides evidence for a regulatory link between the FRB and kinase domains of Tor1p (2006)

Reinke, Aaron, Chen, Jenny C-Y, Aronova, Sofia, Powers, Ted

The target of rapamycin (TOR) kinase is an important regulator of growth in eukaryotic cells. In budding yeast, Tor1p and Tor2p function as part of two distinct protein complexes, TORC1 and TORC2,...

TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae (2004)

Reinke, Aaron, Anderson, Scott, McCaffery, J Michael, Yates, John, Aronova, Sofia, Chu, Stephanie, ...

The Tor1p and Tor2p kinases, targets of the therapeutically important antibiotic rapamycin, function as components of two distinct protein complexes in yeast, termed TOR complex 1 (TORC1) and TORC2....

Tor Kinases Are in Distinct Membrane-associated Protein Complexes in Saccharomyces cerevisiae

Wedaman, Karen P., Reinke, Aaron, Anderson, Scott, Yates, John, McCaffery, J. Michael, Powers, Ted

Tor1p and Tor2p kinases, targets of the immune-suppressive antibiotic rapamycin, are components of a highly conserved signaling network that couples nutrient availability and cell growth. To gain...

Tor Kinases Are in Distinct Membrane-associated Protein Complexes in Saccharomyces cerevisiae

Wedaman, Karen P., Reinke, Aaron, Anderson, Scott, Yates, John, McCaffery, J. Michael, Powers, Ted

Tor1p and Tor2p kinases, targets of the immune-suppressive antibiotic rapamycin, are components of a highly conserved signaling network that couples nutrient availability and cell growth. To gain...