Abdelali Haoudi

Associate Editors (2008)

Mark A. Smith, George Perry, Xiongwei Zhu, Abdelali Haoudi, Neurodegenerative Diseases, Mark A. Smith, ...

distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Human LINE-1 retrotransposon induces DNA damage and apoptosis in cancer cells (2006)

Belgnaoui, S Mehdi, Gosden, Roger G, Semmes, O John, Haoudi, Abdelali

Abstract Background Long interspersed nuclear elements (LINEs), Alu and endogenous retroviruses (ERVs) make up some 45% of human DNA. LINE-1 also called L1, is the most common family of non-LTR...

Functional Clustering Algorithm for High-Dimensional Proteomics Data (2005)

Halima Bensmail, Buddana Aruna, O. John Semmes, Abdelali Haoudi

Clustering proteomics data is a challenging problem for any traditional clustering algorithm. Usually, the number of samples is largely smaller than the number of protein peaks. The use of a...

A novel approach for clustering proteomics data using Bayesian fast Fourier transform (2005)

Bensmail, Halima, Golek, Jennifer, Moody, Michelle M., Semmes, John O., Haoudi, Abdelali

Motivation: Bioinformatics clustering tools are useful at all levels of proteomic data analysis. Proteomics studies can provide a wealth of information and rapidly generate large quantities of data...

A novel approach for clustering proteomics data using Bayesian Fast Fourier Transform (2005)

Bensmail, Halima, Golek, Jennifer, Moody, Michelle M., Semmes, O. John, Haoudi, Abdelali

Motivation: Bioinformatics clustering tools are useful at all levels of proteomic data analysis. Proteomics studies can provide a wealth of information and rapidly generate large quantities of data...

Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53 (2004)

Abdelali Haoudi, O. John Semmes, James M. Mason, Ronald E. Cannon

Retrotransposition of human LINE-1 (L1) element, a major representative non-LTR retrotransposon in the human genome, is known to be a source of insertional mutagenesis. However, nothing is known...

Postgenomics: Proteomics and Bioinformatics in Cancer Research (2003)

Halima Bensmail, Abdelali Haoudi

Now that the human genome is completed, the characterization of the proteins encoded by the sequence remains a challenging task. The study of the complete protein complement of the genome, the...

Postgenomics: Proteomics and Bioinformatics in Cancer Research

Bensmail, Halima, Haoudi, Abdelali

Now that the human genome is completed, the characterization of the proteins encoded by the sequence remains a challenging task. The study of the complete protein complement of the genome, the...

Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53

Haoudi, Abdelali, Semmes, O. John, Mason, James M., Cannon, Ronald E.

Retrotransposition of human LINE-1 (L1) element, a major representative non-LTR retrotransposon in the human genome, is known to be a source of insertional mutagenesis. However, nothing is known...

Functional Clustering Algorithm for High-Dimensional Proteomics Data

Bensmail, Halima, Aruna, Buddana, Semmes, O. John, Haoudi, Abdelali

Clustering proteomics data is a challenging problem for any traditional clustering algorithm. Usually, the number of samples is largely smaller than the number of protein peaks. The use of a...

Telomere elongation (Tel), a new mutation in Drosophila melanogaster that produces long telomeres.

Siriaco, Giorgia M, Cenci, Giovanni, Haoudi, Abdelali, Champion, Larry E, Zhou, Chun, Gatti, Maurizio, ...

In most eukaryotes telomeres are extended by telomerase. Drosophila melanogaster, however, lacks telomerase, and telomere-specific non-LTR retrotransposons, HeT-A and TART, transpose specifically to...

Postgenomics: Proteomics and Bioinformatics in Cancer Research

Bensmail, Halima, Haoudi, Abdelali

Now that the human genome is completed, the characterization of the proteins encoded by the sequence remains a challenging task. The study of the complete protein complement of the genome, the...

Retrotransposition-Competent Human LINE-1 Induces Apoptosis in Cancer Cells With Intact p53

Haoudi, Abdelali, Semmes, O. John, Mason, James M., Cannon, Ronald E.

Retrotransposition of human LINE-1 (L1) element, a major representative non-LTR retrotransposon in the human genome, is known to be a source of insertional mutagenesis. However, nothing is known...

Functional Clustering Algorithm for High-Dimensional Proteomics Data

Bensmail, Halima, Aruna, Buddana, Semmes, O. John, Haoudi, Abdelali

Clustering proteomics data is a challenging problem for any traditional clustering algorithm. Usually, the number of samples is largely smaller than the number of protein peaks. The use of a...

Telomere elongation (Tel), a new mutation in Drosophila melanogaster that produces long telomeres.

Siriaco, Giorgia M, Cenci, Giovanni, Haoudi, Abdelali, Champion, Larry E, Zhou, Chun, Gatti, Maurizio, ...

In most eukaryotes telomeres are extended by telomerase. Drosophila melanogaster, however, lacks telomerase, and telomere-specific non-LTR retrotransposons, HeT-A and TART, transpose specifically to...

PDZ binding motif of HTLV-1 Tax promotes virus-mediated T-cell proliferation in vitro and persistence in vivo

Xie, Li, Yamamoto, Brenda, Haoudi, Abdelali, Semmes, O. John, Green, Patrick L.

HTLV-1 cellular transformation and disease induction is dependent on expression of the viral Tax oncoprotein. PDZ is a modular protein interaction domain used in organizing signaling complexes in...

HTLV-1 Tax Oncoprotein Subverts the Cellular DNA Damage Response via Binding to DNA-dependent Protein Kinase*S⃞

Durkin, Sarah S., Guo, Xin, Fryrear, Kimberly A., Mihaylova, Valia T., Gupta, Saurabh K., Belgnaoui, S. Mehdi, ...

Human T-cell leukemia virus type-1 is the causative agent for adult T-cell leukemia. Previous research has established that the viral oncoprotein Tax mediates the transformation process by impairing...