Achim Tresch

Starr: Simple Tiling Array Analysis of Affymetrix ChIP-chip data (2009)

Zacher, Benedikt, Tresch, Achim

Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay for DNA-protein-binding or post-translational chromatin/histone modifications. As with all high-throughput...

A Bayesian Network View on Nested Effects Models (2009)

Cordula Zeller, Holger Fröhlich, Achim Tresch

Nested effects models (NEMs) are a class of probabilistic models that were designed to reconstruct a hidden signalling structure from a large set of observable effects caused by active interventions...

A Bayesian Network View on Nested Effects Models (2009)

Cordula Zeller, Holger Fröhlich, Achim Tresch

Nested effects models (NEMs) are a class of probabilistic models that were designed to reconstruct a hidden signalling structure from a large set of observable effects caused by active interventions...

2 1 3 (2008)

Achim Tresch, True Model

This exercise will give an introduction to the use of nested effects models (NEMs). There are two packages which implement different variants of nested effects models: nem which was introduced in...

Structure Learning in Nested Effects Models (2008)

Tresch, Achim, Markowetz, Florian

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Structure Learning in Nested Effects Models (2008)

Tresch, Achim, Markowetz, Florian

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Structure Learning in Nested Effects Models (2008)

Tresch, Achim, Markowetz, Florian

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Structure Learning in Nested Effects Models (2008)

Tresch, Achim, Markowetz, Florian

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Array analysis of epilepsy-associated gangliogliomas reveals expression patterns related to aberrant development of neuronal precursors (2008)

Fassunke, Jana, Majores, Michael, Tresch, Achim, Niehusmann, Pitt, Grote, Alexander, Schoch, Susanne, ...

Gangliogliomas, the most frequent neoplasms in patients with pharmacoresistant focal epilepsies, are characterized by histological combinations of glial and dysplastic neuronal elements, a highly...

Analyzing gene perturbation screens with nested effects models in R and bioconductor (2008)

Fröhlich, Holger, Beißbarth, Tim, Tresch, Achim, Kostka, Dennis, Jacob, Juby, Spang, Rainer, ...

Summary: Nested effects models (NEMs) are a class of probabilistic models introduced to analyze the effects of gene perturbation screens visible in high-dimensional phenotypes like microarrays or...

Structure Learning in Nested Effects Models (2007)

Tresch, Achim, Markowetz, Florian

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Identification of aberrant chromosomal regions from gene expression microarray studies applied to human breast cancer (2007)

Buness, Andreas, Kuner, Ruprecht, Ruschhaupt, Markus, Poustka, Annemarie, Sültmann, Holger, Tresch, Achim

Motivation: In cancer, chromosomal imbalances like amplifications and deletions, or changes in epigenetic mechanisms like DNA methylation influence the transcriptional activity. These alterations are...

A Bayesian Network View on Nested Effects Models

Zeller, Cordula, Fröhlich, Holger, Tresch, Achim

Nested effects models (NEMs) are a class of probabilistic models that were designed to reconstruct a hidden signalling structure from a large set of observable effects caused by active interventions...

Structure Learning in Nested Effects Models

Achim Tresch, Florian Markowetz

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs...

Modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models

Anchang, Benedict, Sadeh, Mohammad J., Jacob, Juby, Tresch, Achim, Vlad, Marcel O., Oefner, Peter J., ...

Cellular decision making in differentiation, proliferation, or cell death is mediated by molecular signaling processes, which control the regulation and expression of genes. Vice versa, the...

Analyzing gene perturbation screens with nested effects models in R and bioconductor

Fröhlich, Holger, Beißbarth, Tim, Tresch, Achim, Kostka, Dennis, Jacob, Juby, Spang, Rainer, ...

Summary: Nested effects models (NEMs) are a class of probabilistic models introduced to analyze the effects of gene perturbation screens visible in high-dimensional phenotypes like microarrays or...