Genome-wide discovery of modulators of transcriptional interactions in human B lymphocytes (2005)
Wang, Kai, Nemenman, Ilya, Banerjee, Nilanjana, Margolin, Adam, Califano, Andrea
Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription factor and its target(s). These...
Conditional Network Analysis Identifies Candidate Regulator Genes in Human B Cells (2004)
Wang, Kai, Banerjee, Nilanjana, Margolin, Adam, Nemenman, Ilya, Basso, Katia, Favera, Riccardo, ...
Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology as well as for the...
Greshock, Joel, Naylor, Tara L., Margolin, Adam, Diskin, Sharon, Cleaver, Stephen H., Futreal, P. Andrew, ...
Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology has tremendous potential for...
Greshock, Joel, Naylor, Tara L., Margolin, Adam, Diskin, Sharon, Cleaver, Stephen H., Futreal, P. Andrew, ...
Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology has tremendous potential for...
Greshock, Joel, Naylor, Tara L., Margolin, Adam, Diskin, Sharon, Cleaver, Stephen H., Futreal, P. Andrew, ...
Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology has tremendous potential for...
Greshock, Joel, Naylor, Tara L., Margolin, Adam, Diskin, Sharon, Cleaver, Stephen H., Futreal, P. Andrew, ...
Array-based comparative genomic hybridization (aCGH) is a recently developed tool for genome-wide determination of DNA copy number alterations. This technology has tremendous potential for...
Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, ...
The NOTCH1 signaling pathway directly links extracellular signals with transcriptional responses in the cell nucleus and plays a critical role during T cell development and in the pathogenesis over...
Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia
Palomero, Teresa, Odom, Duncan T., O'Neil, Jennifer, Ferrando, Adolfo A., Margolin, Adam, Neuberg, Donna S., ...
Aberrant expression of 1 or more transcription factor oncogenes is a critical component of the molecular pathogenesis of human T-cell acute lymphoblastic leukemia (T-ALL); however, oncogenic...