CONDOR: a database resource of developmentally associated conserved non-coding elements (2007)
Woolfe, Adam, Goode, Debbie K, Cooke, Julie, Callaway, Heather, Smith, Sarah, Snell, Phil, ...
Abstract Background Comparative genomics is currently one of the most popular approaches to study the regulatory architecture of vertebrate genomes. Fish-mammal genomic comparisons have proved...
Comparative genomics using Fugureveals insights into regulatory subfunctionalization (2007)
Abstract Background A major mechanism for the preservation of gene duplicates in the genome is thought to be mediated via loss or modification of cis -regulatory subfunctions between paralogs...
2007 Woolfe Volume and 8, Issue Elgar4, Article R53 Open Access (2007)
Comparative genomics using Fugu reveals insights into regulatory subfunctionalization
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development (2005)
Adam Woolfe, Martin Goodson, Debbie K. Goode, Phil Snell, Gayle K. McEwen, Tanya Vavouri, ...
Highly conserved non-coding sequences in vertebrate genomes are frequently located around genes involved in development and can direct tissue-specific gene expression in functional assays.
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development (2005)
Adam Woolfe, Martin Goodson, Debbie K. Goode, Phil Snell, Gayle K. McEwen, Tanya Vavouri, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development
Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Ancient duplicated conserved noncoding elements in vertebrates: A genomic and functional analysis
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Highly Conserved Non-Coding Sequences Are Associated with Vertebrate Development
Woolfe, Adam, Goodson, Martin, Goode, Debbie K, Snell, Phil, McEwen, Gayle K, Vavouri, Tanya, ...
In addition to protein coding sequence, the human genome contains a significant amount of regulatory DNA, the identification of which is proving somewhat recalcitrant to both in silico and functional...
Ancient duplicated conserved noncoding elements in vertebrates: A genomic and functional analysis
McEwen, Gayle K., Woolfe, Adam, Goode, Debbie, Vavouri, Tanya, Callaway, Heather, Elgar, Greg
Fish–mammal genomic comparisons have proved powerful in identifying conserved noncoding elements likely to be cis-regulatory in nature, and the majority of those tested in vivo have been shown to...
Comparative genomics using Fugu reveals insights into regulatory subfunctionalization
Fish-mammal genomic alignments were used to compare over 800 conserved non-coding elements that associate with genes that have undergone fish-specific duplication and retention, revealing a pattern...