Adeel Safdar

Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation (2008)

Safdar, Adeel, Yardley, Nicholas J., Snow, Rodney, Melov, Simon, Tarnopolsky, Mark A.

Creatine monohydrate (CrM) supplementation has been shown to increase fat-free mass and muscle power output possibly via cell swelling. Little is known about the cellular response to CrM. We...

Creatine Monohydrate and Conjugated Linoleic Acid Improve Strength and Body Composition Following Resistance Exercise in Older Adults

Tarnopolsky, Mark, Zimmer, Andrew, Paikin, Jeremy, Safdar, Adeel, Aboud, Alissa, Pearce, Erin, ...

Aging is associated with lower muscle mass and an increase in body fat. We examined whether creatine monohydrate (CrM) and conjugated linoleic acid (CLA) could enhance strength gains and improve body...

Short-term sprint interval versus traditional endurance training: similar initial adaptations in human skeletal muscle and exercise performance

Gibala, Martin J, Little, Jonathan P, Van Essen, Martin, Wilkin, Geoffrey P, Burgomaster, Kirsten A, Safdar, Adeel, ...

Brief, intense exercise training may induce metabolic and performance adaptations comparable to traditional endurance training. However, no study has directly compared these diverse training...

miRNA in the Regulation of Skeletal Muscle Adaptation to Acute Endurance Exercise in C57Bl/6J Male Mice

Safdar, Adeel, Abadi, Arkan, Akhtar, Mahmood, Hettinga, Bart P., Tarnopolsky, Mark A.

MicroRNAs (miRNAs) are evolutionarily conserved small non-coding RNA species involved in post-transcriptional gene regulation. In vitro studies have identified a small number of skeletal...

Limb Immobilization Induces a Coordinate Down-Regulation of Mitochondrial and Other Metabolic Pathways in Men and Women

Abadi, Arkan, Glover, Elisa I., Isfort, Robert J., Raha, Sandeep, Safdar, Adeel, Yasuda, Nobuo, ...

Advancements in animal models and cell culture techniques have been invaluable in the elucidation of the molecular mechanisms that regulate muscle atrophy. However, few studies have examined muscle...