Gene-set analysis and reduction (2009)
Dinu, Irina, Potter, John D., Mueller, Thomas, Liu, Qi, Adewale, Adeniyi J., Jhangri, Gian S., ...
Gene-set analysis aims to identify differentially expressed gene sets (pathways) by a phenotype in DNA microarray studies. We review here important methodological aspects of gene-set analysis and...
New criteria for robust integer-valued designs in linear models (2008)
www.elsevier.com/locate/csda
Irina Dinu, Qi Liu, John D. Potter, Adeniyi J. Adewale, Gian S. Jhangri, Thomas Mueller, ...
Gene-set analysis of microarray data evaluates biological pathways, or gene sets, for their differential expression by a phenotype of interest. In contrast to the analysis of individual genes,...
A Cautionary Note on the Evaluation of Biomarkers of Subtypes of a Single Disease (2008)
Adewale, Adeniyi J., Liu, Qi, Dinu, Irina, Lampe, Paul D., Mitchell, Bree L., Yasui, Yutaka
Heterogeneity in the molecular characteristics of a disease presents a challenge to investigators attempting to identify biomarkers of the disease. Preceding the biomarker discovery effort with...
Comparative evaluation of gene-set analysis methods (2007)
Liu, Qi, Dinu, Irina, Adewale, Adeniyi J, Potter, John D, Yasui, Yutaka
Abstract Background Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated with a binary...
Improving gene set analysis of microarray data by SAM-GS (2007)
Dinu, Irina, Potter, John D, Mueller, Thomas, Liu, Qi, Adewale, Adeniyi J, Jhangri, Gian S, ...
Abstract Background Gene-set analysis evaluates the expression of biological pathways, or a priori defined gene sets, rather than that of individual genes, in association with a binary phenotype, and...
Newton, Mandi S, Estabrooks, Carole A, Norton, Peter, Birdsell, Judy M, Adewale, Adeniyi J, Thornley, Richard
Abstract Background Canadian funding agencies are no longer content to support research that solely advances scientific knowledge, and key directives are now in place to promote research transfer to...
Robust designs for misspecified logistic models (0000)
We develop criteria that generate robust designs and use such criteria for the construction of designs that insure against possible misspecifications in logistic regression models. The design...
Newton, Mandi S, Estabrooks, Carole A, Norton, Peter, Birdsell, Judy M, Adewale, Adeniyi J, Thornley, Richard
Improving gene set analysis of microarray data by SAM-GS
Dinu, Irina, Potter, John D, Mueller, Thomas, Liu, Qi, Adewale, Adeniyi J, Jhangri, Gian S, ...
Comparative evaluation of gene-set analysis methods
Liu, Qi, Dinu, Irina, Adewale, Adeniyi J, Potter, John D, Yasui, Yutaka
Knowledge translation and research careers: Mode I and Mode II activity among health researchers
Estabrooks, Carole A., Norton, Peter, Birdsell, Judy M., Newton, Mandi S., Adewale, Adeniyi J., Thornley, Richard
Defining knowledge translation activities using Gibbons and Nowotny's Mode I and II forms of knowledge production, health researcher (NÂ =Â 240) characteristics are compared with their knowledge...
Dinu, Irina, Liu, Qi, Potter, John D., Adewale, Adeniyi J., Jhangri, Gian S., Mueller, Thomas, ...
Gene-set analysis of microarray data evaluates biological pathways, or gene sets, for their differential expression by a phenotype of interest. In contrast to the analysis of individual genes,...
Robust designs for misspecified logistic models
We develop criteria that generate robust designs and use such criteria for the construction of designs that insure against possible misspecifications in logistic regression models. The design...