Adam A. Margolin, Teresa Palomero, Pavel Sumazin, Andrea Califano, Adolfo Ferrando, Gustavo A. Stolovitzky
ChIP-on-chip has emerged as a powerful tool to dissect the complex network of regulatory interactions between transcription factors and their targets. However, most ChIP-on-chip analysis methods use...
The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, ...
Recent studies have shown that activating mutations of NOTCH1 are responsible for the majority of T cell acute lymphoblastic leukemia (T-ALL) cases. Most of these mutations truncate its C-terminal...