Characterization of Helicobacter pylori lytic transglycosylases Slt and MltD. (2007)
Chaput, Catherine, Labigne, Agnès, Boneca, Ivo G
Peptidoglycan (PG) is a cell wall heteropolymer that is essential for cell integrity. PG hydrolases participate in correct assembly of the PG layer and have been shown to be required for cell...
Role of AmiA in the Morphological Transition of Helicobacter pylori and in Immune Escape (2006)
Catherine Chaput, Chantal Ecobichon, Nadège Cayet, Stephen E. Girardin, Catherine Werts, Stéphanie Guadagnini, ...
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms....
Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape. (2006)
Chaput, Catherine, Ecobichon, Chantal, Cayet, Nadège, Girardin, Stephen E, Werts, Catherine, Guadagnini, Stéphanie, ...
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms....
Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape. (2006)
Chaput, Catherine, Ecobichon, Chantal, Cayet, Nadège, Girardin, Stephen E, Werts, Catherine, Guadagnini, Stéphanie, ...
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms....
Latham, Stephanie R., Owen, Robert J., Elviss, Nicola C., Labigne, Agnès, Jenks, Peter J.
Antimicrobial resistance in Helicobacter pylori is a serious and increasing problem, and the development of rapid, reliable methods for detecting resistance would greatly improve the selection of...
Jenks, Peter J., Ferrero, Richard L., Tankovic, Jacques, Thiberge, Jean-Michel, Labigne, Agnès
The main objectives of this study were to determine whether the nitroreductase enzyme encoded by the rdxA gene of Helicobacter pylori was responsible for reductive activation of nitrofurantoin and...
Helicobacter pylori Heat Shock Protein A: Serologic Responses and Genetic Diversity
Ng, Enders K. W., Thompson, Stuart A., Pérez-Pérez, Guillermo I., Kansau, Imad, Van Der Ende, Arie, Labigne, Agnès, ...
Helicobacter pylori synthesizes an unusual GroES homolog, heat shock protein A (HspA). The present study was aimed at an assessment of the serological response to HspA in a group of Chinese patients...
We investigated whether Helicobacter pylori cells actively secrete proteins such as the urease subunits UreA and UreB and the GroES and GroEL homologs HspA and HspB or whether these proteins were...
Ferrero, Richard L., Thiberge, Jean-Michel, Huerre, Michel, Labigne, Agnès
A model permitting the establishment of persistent Helicobacter pylori infection in mice was recently described. To evaluate murine immune responses to H. pylori infection, specific-pathogen-free...
Skouloubris, Stéphane, Thiberge, Jean-Michel, Labigne, Agnès, De Reuse, Hilde
We produced defined isogenic Helicobacter pylori ureI mutants to investigate the function of UreI, the product of one of the genes of the urease cluster. The insertion of a cat cassette had a strong...
O'Rourke, Eyleen J., Chevalier, Catherine, Pinto, A. Viviana, Thiberge, Jean Michel, Ielpi, Luis, Labigne, Agnès, ...
Helicobacter pylori elicits an oxidative stress during host colonization. This oxidative stress is known to cause lesions in the host DNA. Here we addressed the question as to whether the pathogen...
A revised annotation and comparative analysis of Helicobacter pylori genomes
Boneca, Ivo G., Reuse, Hilde De, Epinat, Jean-Charles, Pupin, Maude, Labigne, Agnès, Moszer, Ivan
Huge amounts of genomic information are currently being generated. Therefore, biologists require structured, exhaustive and comparative databases. The PyloriGene database...
Presence of Active Aliphatic Amidases in Helicobacter Species Able To Colonize the Stomach
Bury-Moné, Stéphanie, Skouloubris, Stéphane, Dauga, Catherine, Thiberge, Jean-Michel, Dailidiene, Daiva, Berg, Douglas E., ...
Ammonia production is of great importance for the gastric pathogen Helicobacter pylori as a nitrogen source, as a compound protecting against gastric acidity, and as a cytotoxic molecule. In addition...
Role of AmiA in the Morphological Transition of Helicobacter pylori and in Immune Escape
Chaput, Catherine, Ecobichon, Chantal, Cayet, Nadège, Girardin, Stephen E, Werts, Catherine, Guadagnini, Stéphanie, ...
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms....
Latham, Stephanie R., Owen, Robert J., Elviss, Nicola C., Labigne, Agnès, Jenks, Peter J.
Antimicrobial resistance in Helicobacter pylori is a serious and increasing problem, and the development of rapid, reliable methods for detecting resistance would greatly improve the selection of...
Jenks, Peter J., Ferrero, Richard L., Tankovic, Jacques, Thiberge, Jean-Michel, Labigne, Agnès
The main objectives of this study were to determine whether the nitroreductase enzyme encoded by the rdxA gene of Helicobacter pylori was responsible for reductive activation of nitrofurantoin and...
Helicobacter pylori Heat Shock Protein A: Serologic Responses and Genetic Diversity
Ng, Enders K. W., Thompson, Stuart A., Pérez-Pérez, Guillermo I., Kansau, Imad, Van Der Ende, Arie, Labigne, Agnès, ...
Helicobacter pylori synthesizes an unusual GroES homolog, heat shock protein A (HspA). The present study was aimed at an assessment of the serological response to HspA in a group of Chinese patients...
We investigated whether Helicobacter pylori cells actively secrete proteins such as the urease subunits UreA and UreB and the GroES and GroEL homologs HspA and HspB or whether these proteins were...
Ferrero, Richard L., Thiberge, Jean-Michel, Huerre, Michel, Labigne, Agnès
A model permitting the establishment of persistent Helicobacter pylori infection in mice was recently described. To evaluate murine immune responses to H. pylori infection, specific-pathogen-free...
Skouloubris, Stéphane, Thiberge, Jean-Michel, Labigne, Agnès, De Reuse, Hilde
We produced defined isogenic Helicobacter pylori ureI mutants to investigate the function of UreI, the product of one of the genes of the urease cluster. The insertion of a cat cassette had a strong...
O'Rourke, Eyleen J., Chevalier, Catherine, Pinto, A. Viviana, Thiberge, Jean Michel, Ielpi, Luis, Labigne, Agnès, ...
Helicobacter pylori elicits an oxidative stress during host colonization. This oxidative stress is known to cause lesions in the host DNA. Here we addressed the question as to whether the pathogen...
A revised annotation and comparative analysis of Helicobacter pylori genomes
Boneca, Ivo G., Reuse, Hilde De, Epinat, Jean-Charles, Pupin, Maude, Labigne, Agnès, Moszer, Ivan
Huge amounts of genomic information are currently being generated. Therefore, biologists require structured, exhaustive and comparative databases. The PyloriGene database...
Presence of Active Aliphatic Amidases in Helicobacter Species Able To Colonize the Stomach
Bury-Moné, Stéphanie, Skouloubris, Stéphane, Dauga, Catherine, Thiberge, Jean-Michel, Dailidiene, Daiva, Berg, Douglas E., ...
Ammonia production is of great importance for the gastric pathogen Helicobacter pylori as a nitrogen source, as a compound protecting against gastric acidity, and as a cytotoxic molecule. In addition...
Role of AmiA in the Morphological Transition of Helicobacter pylori and in Immune Escape
Chaput, Catherine, Ecobichon, Chantal, Cayet, Nadège, Girardin, Stephen E, Werts, Catherine, Guadagnini, Stéphanie, ...
The human gastric pathogen Helicobacter pylori is responsible for peptic ulcers and neoplasia. Both in vitro and in the human stomach it can be found in two forms, the bacillary and coccoid forms....
Characterization of Helicobacter pylori Lytic Transglycosylases Slt and MltD▿ †
Chaput, Catherine, Labigne, Agnès, Boneca, Ivo G.
Peptidoglycan (PG) is a cell wall heteropolymer that is essential for cell integrity. PG hydrolases participate in correct assembly of the PG layer and have been shown to be required for cell...
Channel-mediated potassium uptake in Helicobacter pylori is essential for gastric colonization
Stingl, Kerstin, Brandt, Sonja, Uhlemann, Eva-Maria, Schmid, Roland, Altendorf, Karlheinz, Zeilinger, Carsten, ...
To date, the biological role of prokaryotic K+ channels remains unknown. Helicobacter pylori contains a gene encoding a putative K+ channel (HpKchA) of the two-transmembrane RCK (regulation of K+...
Using Macro-Arrays to Study Routes of Infection of Helicobacter pylori in Three Families
Raymond, Josette, Thiberge, Jean-Michel, Kalach, Nicolas, Bergeret, Michel, Dupont, Christophe, Labigne, Agnès, ...
Bury-Moné, Stéphanie, Mendz, George L., Ball, Graham E., Thibonnier, Marie, Stingl, Kerstin, Ecobichon, Chantal, ...
Carbon dioxide occupies a central position in the physiology of Helicobacter pylori owing to its capnophilic nature, the large amounts of carbon dioxide produced by urease-mediated urea hydrolysis,...
Boneca, Ivo G., Ecobichon, Chantal, Chaput, Catherine, Mathieu, Aurélie, Guadagnini, Stéphanie, Prévost, Marie-Christine, ...
The Escherichia coli-Helicobacter pylori shuttle vector pHeL2 was modified to introduce the inducible LacIq-pTac system of E. coli, in which the promoters were engineered to be under the control of...