Aimin Zhou

Benchmarking Algorithms for Dynamic Travelling Salesman Problems (2008)

Lishan Kang, Aimin Zhou, Bob Mckay, Yan Li, Zhuo Kang

Abstract- Dynamic optimisation problems are becoming increasingly important; meanwhile, progress in optimisation techniques and in computational resources are permitting the development of effective...

Prediction-based Population Re-initialization for Evolutionary Dynamic Multi-objective Optimization (2008)

Aimin Zhou, Yaochu Jin, Qingfu Zhang, Bernhard Sendhoff, Edward Tsang

Abstract. Optimization in changing environment is a challenging task, especially when multiple objectives are to be optimized simultaneously. The basic idea to address dynamic optimization problems...

Ovarian Cancer G Protein Coupled Receptor 1, a New Metastasis Suppressor Gene in Prostate Cancer (2007)

Singh, Lisam Shanjukumar, Berk, Michael, Oates, Rhonda, Zhao, Zhenwen, Tan, Haiyan, Jiang, Ying, ...

Background Metastasis is a process by which tumors spread from primary organs to other sites in the body and is the major cause of death for cancer patients. The ovarian cancer G protein–coupled...

Modelling the population distribution in multi-objective optimization by generative topographic mapping (2006)

Aimin Zhou, Qingfu Zhang, Yaochu Jin, Bernhard Sendhoff, Edward Tsang

Abstract. Under mild conditions, the Pareto set of a continuous multi-objective optimization problem exhibits certain regularity. We have recently advocated taking into consideration such regularity...

Combining model-based and genetics-based offspring generation for multi-objective optimization using a convergence criterion (2006)

Aimin Zhou, Yaochu Jin, Qingfu Zhang, Bernhard Sendhoff, Edward Tsang

Abstract — In our previous work [1], it has been shown that the performance of multi-objective evolutionary algorithms can be greatly enhanced if the regularity in the distribution of...

A model-based evolutionary algorithm for biobjective optimization (2005)

Aimin Zhou, Qingfu Zhang, Yaochu Jin, Edward Tsang

Abstract- The Pareto optimal solutions to a multiobjective optimization problem often distribute very regularly in both the decision space and the objective space. Most existing evolutionary...

A model-based evolutionary algorithm for biobjective optimization (2005)

Aimin Zhou, Qingfu Zhang, Yaochu Jin, Edward Tsang, Tatsuya Okabe

Abstract- The Pareto optimal solutions to a multiobjective optimization problem often distribute very regularly in both the decision space and the objective space. Most existing evolutionary...

A model-based evolutionary algorithm for biobjective optimization (2005)

Aimin Zhou, Qingfu Zhang, Yaochu Jin, Edward Tsang, Tatsuya Okabe

Abstract- The Pareto optimal solutions to a multiobjective optimization problem often distribute very regularly in both the decision space and the objective space. Most existing evolutionary...

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

Der, Sandy D., Zhou, Aimin, Williams, Bryan R. G., Silverman, Robert H.

The pleiotropic activities of interferons (IFNs) are mediated primarily through the transcriptional regulation of many downstream effector genes. The mRNA profiles from IFN-α, -β, or -γ treatments...

Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH2-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways

Iordanov, Mihail S., Paranjape, Jayashree M., Zhou, Aimin, Wong, John, Williams, Bryan R. G., Meurs, Eliane F., ...

Double-stranded RNA (dsRNA) accumulates in virus-infected mammalian cells and signals the activation of host defense pathways of the interferon system. We describe here a novel form of...

RNase L-Independent Specific 28S rRNA Cleavage in Murine Coronavirus-Infected Cells

Banerjee, Sangeeta, An, Sungwhan, Zhou, Aimin, Silverman, Robert H., Makino, Shinji

We characterized a novel 28S rRNA cleavage in cells infected with the murine coronavirus mouse hepatitis virus (MHV). The 28S rRNA cleavage occurred as early as 4 h postinfection (p.i.) in...

The Vaccinia Virus A18R DNA Helicase Is a Postreplicative Negative Transcription Elongation Factor

Xiang, Ying, Simpson, David A., Spiegel, Jason, Zhou, Aimin, Silverman, Robert H., Condit, Richard C.

Loss of vaccinia virus A18R gene function results in an aberrant transcription profile termed promiscuous transcription, defined as transcription within regions of the genome which are normally...

Phospholipid Scramblase 1 Potentiates the Antiviral Activity of Interferon

Dong, Beihua, Zhou, Quansheng, Zhao, Ji, Zhou, Aimin, Harty, Ronald N., Bose, Santanu, ...

Phospholipid scramblase 1 (PLSCR1) is an interferon (IFN)- and growth factor-inducible, calcium-binding protein that either inserts into the plasma membrane or binds DNA in the nucleus depending on...

Apo2L/TRAIL and Bcl-2–related proteins regulate type I interferon–induced apoptosis in multiple myeloma

Chen, Quan, Gong, Bendi, Mahmoud-Ahmed, Ashraf S., Zhou, Aimin, Hsi, Eric D., Hussein, Mohamad, ...

It has been reported that interferons (IFNs) may have antitumor activity in multiple myeloma (MM). The mechanism for their effect on MM, however, remains elusive. This study shows that IFN-α and...

Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays

Der, Sandy D., Zhou, Aimin, Williams, Bryan R. G., Silverman, Robert H.

The pleiotropic activities of interferons (IFNs) are mediated primarily through the transcriptional regulation of many downstream effector genes. The mRNA profiles from IFN-α, -β, or -γ treatments...

Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH2-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways

Iordanov, Mihail S., Paranjape, Jayashree M., Zhou, Aimin, Wong, John, Williams, Bryan R. G., Meurs, Eliane F., ...

Double-stranded RNA (dsRNA) accumulates in virus-infected mammalian cells and signals the activation of host defense pathways of the interferon system. We describe here a novel form of...

RNase L-Independent Specific 28S rRNA Cleavage in Murine Coronavirus-Infected Cells

Banerjee, Sangeeta, An, Sungwhan, Zhou, Aimin, Silverman, Robert H., Makino, Shinji

We characterized a novel 28S rRNA cleavage in cells infected with the murine coronavirus mouse hepatitis virus (MHV). The 28S rRNA cleavage occurred as early as 4 h postinfection (p.i.) in...

The Vaccinia Virus A18R DNA Helicase Is a Postreplicative Negative Transcription Elongation Factor

Xiang, Ying, Simpson, David A., Spiegel, Jason, Zhou, Aimin, Silverman, Robert H., Condit, Richard C.

Loss of vaccinia virus A18R gene function results in an aberrant transcription profile termed promiscuous transcription, defined as transcription within regions of the genome which are normally...

Phospholipid Scramblase 1 Potentiates the Antiviral Activity of Interferon

Dong, Beihua, Zhou, Quansheng, Zhao, Ji, Zhou, Aimin, Harty, Ronald N., Bose, Santanu, ...

Phospholipid scramblase 1 (PLSCR1) is an interferon (IFN)- and growth factor-inducible, calcium-binding protein that either inserts into the plasma membrane or binds DNA in the nucleus depending on...