Ajay Singh

Publication List Details

Period

1983 - 2009

Number

34

Co-Authors

Effect of Cycloart-24-EN-3β-OL From Euphorbia Royleana Latex Onneuro-enzyme AChE and Oxidative Metabolism of Freshwater Fish, Channa Punctatus   (2009)

Tiwari, Sudhanshu, Pandeya, R.P., Singh, Ajay

Cycloart-24-en-3β-ol isolated from Euphorbia royleana latex possesses potent piscicidal activity against freshwater predatory fish Channa Punctatus   . Their short as well as long-term exposure...

Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport. (2009)

Singh, Ajay, Kong, Qingzhong, Luo, Xiu, Petersen, Robert B., Meyerson, Howard, Singh, Neena, ...

Despite overwhelming evidence implicating the prion protein (PrP) in prion disease pathogenesis, the normal function of this cell surface glycoprotein remains unclear. In previous reports we...

A prospective evaluation of renal replacement therapy modality eligibility (2009)

Mendelssohn, David C., Mujais, Salim K., Soroka, Steven D., Brouillette, John, Takano, Tomoko, Barre, Paul E., ...

Background. Patient eligibility for renal replacement therapy (RRT) modalities is frequently debated, but little prospective data are available from large patient cohorts. Methods. We prospectively...

TABLE OF CONTENTS (2008)

Olph Hall, Maged Dessouky, Lei Zhang, Ajay Singh, Vishal Pate, Maged Dessouky, ...

This paper has been mechanically scanned. Some errors may have been inadvertently introduced.

The Potential Of Nutraceuticals (2008)

Anuj Malik, Pradeep Kumar, Niranjan Kaushik, Ajay Singh

The nutraceuticals: food or part of food plays a significant role that modifies and maintains normal physiological function that maintaining healthy human beings. A number of nutraceuticals are...

Synthesis of novel fluorophores for labelling of oligonucleotides (2008)

Singh, Ajay, Singh, Ramendra K.

Some novel fluorophores, viz. 2-(4-Carboxymethyl-naphthalene-1-carbonyl)-benzoic acid (1), 7, 12 –Dioxo-7, 12 dihydrobenzo[a] anthracene 5-yl]-acetic acid (2),...

On Phases of Generic Toric Singularities (2007)

Sarkar, Tapobrata, Singh, Ajay

We systematically study the phases of generic toric singularities, using methods initiated in hep-th/0612046. These correspond to Gauged Linear Sigma Models with arbitrary charges. We show that...

A chimeric cysteine protease of Plasmodium berghei engineered to resemble the Plasmodium falciparum protease falcipain-2 (2007)

Singh, Ajay, Walker, K. Jordan, Sijwali, Puran S., Lau, Anthony L., Rosenthal, Philip J.

The cysteine proteases falcipain-2 and falcipain-3 are hemoglobinases and potential targets for chemotherapy directed against Plasmodium falciparum, the most important human malaria parasite. Most in...

EFFECT OF SUB-LETHAL CONCENTRATIONS OF CODIAEUM VARIEGATUM LATEX ON FRESHWATER TARGET SNAIL LYMNAEA ACUMINATA AND NON-TARGET FISH CHANNA PUNCTATUS (2004)

Singh, Ajay; Natural Product Laboratory Department Of Zoology DDU, Gorakhpur University, Gorakhpur-273 009 (U.P) INDIA ; Ajay_s@sancharnet.in

The latex of Codiaeum variegatum plant (Euphorbiaceae) was found to have high molluscicidal activity against freshwater snail Lymnaea acuminata. Exposure of sub-lethal doses (0.15 DW,mg/L and 0.30...

TOXICITY OF NERIUM INDICUM AND EUPHORBIA ROYLEANA LATTICES AGAINST CULEX QUINQUEFASCIATUS MOSQUITO LARVAE (2004)

Singh, Ajay; Department Of Zoology, D.D.U. Gorakhpur University Gorakhpur-273009 (U.P.) India; Ajay_s@sancharnet.in

Different dilutions of aqueous and methanolic extracts of lattices of Nerium indicum (Apocynaceae) and Euphorbia royleana (Euphorbiaceae) were administered for 24h and 48h to the Culex...

ADDRESSING "BEHIND THE SCENES" ECOLOGICAL CONCERNS ASSOCIATED WITH THE DESIGN, CONSTRUCTION, OPERATION AND MAINTENANCE OF AN URBAN TRANSPORTATION SYSTEM- A NEW YORK CITY TRANSIT PERSPECTIVE ON SUSTAINABILITY (2003)

Singh, Ajay, Ramdahin, Dennis, Topielski, Bogdan, Raman, Ramesh Raman

In 1999, The New York City Transit's (NYCT) Department of Capital Program Management achieved ISO14001 certification- Environmental Management Systems. Today, sustainable design is an integral part...

Letter to Editor - We need to think and act (2003)

Dr. Ajay Singh

During the Annual conference of APSI (Bihar-Jharkhand) on 15-16th Feb 2003, the honourable Health minister of Jharkhand, Dr. Dinesh Kumar Sarangi, in his Inaugural address raised few very sensitive...

Metabolic Changes in Freshwater Fish Channa punctatus Due to Stem-bark Extract of Croton tiglium (2003)

Ram P. Yadav, Digvijay Singh, S. K. Singh, Ajay Singh

The exposure to fish over 96 h to sub-lethal doses 8.24 mg, DW L-1 and 16.48 mg, DW L -1 of stem-bark extracts of Croton tiglium of family Euphorbiaceae significantly altered the level of total...

Toxicity of Euphorbia tirucalli Plant Against Freshwater Target and Non-target Organisms (2003)

Sudhanshu Tiwari, Pratibha Singh, Ajay Singh

The present paper deals with the molluscicidal activity of dried powder of latex and stem bark of Euphorbia tirucalli (Family- Euphorbiaceae) against fresh water snail Lymnaea (Radix) acuminata...

Molluscicidal and Anti-cholinesterase Activity of Alstonia scholaris Plant Against Freshwater Snail Lymnaea acuminata (2003)

Sunil Kumar Singh, Ajay Singh

Alstonia scholaris (Family-Apocynaceae) is a common medicinal plant of India. The aqueous as well as partially purified extracts of stem bark and leaf of Alstonia scholaris has molluscicidal as well...

Evaluation of ITS Technology for Bus Transit Systems (1999)

Hall, Randolph, Dessouky, Maged, Zhang, Lei, Singh, Ajay, Patel, Vishal

Recently, bus transit service providers have begun to adopt Intelligent Transportation Systems (ITS) technologies such as Global Positioning Systems (GPS) and Mobile Data Terminals. These systems...

User's Manual for Transit ITS Simulator (TRAN-ITS) (1999)

Dessouky, Maged, Zhang, Lei, Singh, Ajay, Hall, Randolph

This report describes a simulation model developed to evaluate the impact of using Intelligent Transportation Systems (ITS), such as Global Positioning Systems (GPS) for bus tracking, on controlling...

TRANSIT ITS SIMULATOR (1997)

Maged Dessouky, Ajay Singh, Maged Dessouky, Ajay Singh

This paper has been mechanically scanned. Some errors may have been inadvertently introduced.

An Integrated Instrumentation Environment for Multiprocessors (1983)

Zary Segall, Ajay Singh, Richard T. Snodgrass, Anita K. Jones, Senior Member, ...

Abstract-This paper introduces the concept ofan integrated instrumentation environment (IIE) for multiprocessors. The primary objective ofsuch an environment is to assist the user in the process of...

Comparison of Efficacies of Cysteine Protease Inhibitors against Five Strains of Plasmodium falciparum

Singh, Ajay, Rosenthal, Philip J.

Falcipain-2, a cysteine protease and essential hemoglobinase of Plasmodium falciparum, is a potential antimalarial drug target. We compared the falcipain-2 sequences and sensitivities to cysteine...

Biotransformation of Hydroxylaminobenzene and Aminophenol by Pseudomonas putida 2NP8 Cells Grown in the Presence of 3-Nitrophenol

Zhao, Jian-Shen, Singh, Ajay, Huang, Xiao-Dong, Ward, Owen P.

Biotransformation products of hydroxylaminobenzene and aminophenol produced by 3-nitrophenol-grown cells of Pseudomonas putida 2NP8, a strain grown on 2- and 3-nitrophenol, were characterized....

Antimalarial Activities of Novel Synthetic Cysteine Protease Inhibitors

Lee, Belinda J., Singh, Ajay, Chiang, Peggy, Kemp, Scott J., Goldman, Erick A., Weinhouse, Michael I., ...

Among promising new targets for antimalarial chemotherapy are the cysteine protease hemoglobinases falcipain-2 and falcipain-3. We evaluated the activities of synthetic peptidyl aldehyde and...

Recent Advances in Petroleum Microbiology

Van Hamme, Jonathan D., Singh, Ajay, Ward, Owen P.

Recent advances in molecular biology have extended our understanding of the metabolic processes related to microbial transformation of petroleum hydrocarbons. The physiological responses of...

Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.

Singh, Ajay, Shenai, Bhaskar R, Choe, Youngchool, Gut, Jiri, Sijwali, Puran S, Craik, Charles S, ...

Cysteine proteases of Plasmodium falciparum, known as falcipains, have been identified as haemoglobinases and potential drug targets. As anti-malarial drug discovery requires the analysis of...

Identification and biochemical characterization of vivapains, cysteine proteases of the malaria parasite Plasmodium vivax.

Na, Byoung-Kuk, Shenai, Bhaskar R, Sijwali, Puran S, Choe, Youngchool, Pandey, Kailash C, Singh, Ajay, ...

Cysteine proteases play important roles in the life cycles of malaria parasites. Cysteine protease inhibitors block haemoglobin hydrolysis and development in Plasmodium falciparum, suggesting that...

Selective Suppression of NF-kBp65 in Hepatitis Virus-Infected Pregnant Women Manifesting Severe Liver Damage and High Mortality

Prusty, Bhupesh K, Hedau, Suresh, Singh, Ajay, Kar, Premasis, Das, Bhudev C

Fulminant hepatitis in Asian pregnant women is generally caused by hepatitis E virus infection, and extremely high mortality is most common in them. Decreased cell-mediated immunity is considered a...

Prion Protein Modulates Cellular Iron Uptake: A Novel Function with Implications for Prion Disease Pathogenesis

Singh, Ajay, Mohan, Maradumane L., Isaac, Alfred Orina, Luo, Xiu, Petrak, Jiri, Vyoral, Daniel, ...

Converging evidence leaves little doubt that a change in the conformation of prion protein (PrPC) from a mainly α-helical to a β-sheet rich PrP-scrapie (PrPSc) form is the main event responsible...

Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders

Singh, Ajay, Isaac, Alfred Orina, Luo, Xiu, Mohan, Maradumane L., Cohen, Mark L., Chen, Fusong, ...

Neurotoxicity in all prion disorders is believed to result from the accumulation of PrP-scrapie (PrPSc), a β-sheet rich isoform of a normal cell-surface glycoprotein, the prion protein (PrPC)....

Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport

Singh, Ajay, Kong, Qingzhong, Luo, Xiu, Petersen, Robert B., Meyerson, Howard, Singh, Neena

Despite overwhelming evidence implicating the prion protein (PrP) in prion disease pathogenesis, the normal function of this cell surface glycoprotein remains unclear. In previous reports we...