Ake Borg

Genetic Profiling Differentiates Second Primary Tumors from Metastases in Adult Metachronous Soft Tissue Sarcoma (2009)

Josefin Fernebro, Ana Carneiro, Anders Rydholm, Henryk A. Domanski, Anna Karlsson, Åke Borg, ...

Purpose. Patients with soft tissue sarcomas (STS) are at increased risk of second primary malignancies, including a second STS, but distinction between metastases and a second primary STS is...

Gene products of chromosome 11q and their association with CCND1 gene amplification and tamoxifen resistance in premenopausal breast cancer (2008)

Lundgren, Katja, Holm, Karolina, Nordenskjöld, Bo, Borg, Ake, Landberg, Goran

Introduction: The amplification event occurring at chromosome locus 11q13, reported in several different cancers, includes a number of potential oncogenes. We have previously reported amplification...

Cytogenetic characterization and gene expression profiling of the trastuzumab-resistant breast cancer cell line JIMT-1. (2007)

Rennstam, Karin, Jonsson, Goran, Tanner, Minna, Bendahl, Par-Ola, Staaf, Johan, Kapanen, Anita I, ...

Abstract is not available

High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization. (2007)

Jonsson, Goran, Staaf, Johan, Olsson, Eleonor, Heidenblad, Markus, Vallon-Christersson, Johan, Osoegawa, Kazutoyo, ...

Abstract is not available

Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma. (2007)

Gruvberger Saal, Sofia K, Bendahl, Par-Ola, Saal, Lao H, Laakso, Mervi, Hegardt, Cecilia, Edén, Patrik, ...

Abstract is not available

Absence of the common IGF1 19 CA-repeat allele is more common among BRCA1 mutation carriers than among non-carriers from BRCA1 families. (2007)

Henningson, Maria, Bageman, Erika, Sandberg, Therese, Borg, Ake, Olsson, Hakan, Jernstrom, Helena

Abstract is not available

Tiling resolution array CGH, expression, and methylation analyses of dup(1q) in Burkitt lymphomas and pediatric high hyperdiploid acute lymphoblastic leukemias reveal clustered near-centromeric breakpoints and overexpression of genes in 1q22-32.3. (2007)

Davidsson, Josef, Andersson, Anna, Paulsson, Kajsa, Heidenblad, Markus, Isaksson, Margareth, Borg, Ake, ...

Abstract is not available

Microarray analysis of gliomas reveals chromosomal position-associated gene expression patterns and identifies potential immunotherapy targets. (2007)

Persson, Oscar, Krogh, Morten, Saal, Lao, Englund, Elisabet, Liu, Jian, Parsons, Ramon, ...

Abstract is not available

The molecular signature of MDS stem cells supports a stem cell origin of 5q- myelodysplastic syndromes. (2007)

Nilsson, Lars, Eden, Patrik, Olsson, Eleonor, Mansson, Robert, Astrand-Grundstrom, Ingbritt, Strombeck, Bodil, ...

Abstract is not available

Robust smooth segmentation approach for array CGH data analysis. (2007)

Huang, Jian, Gusnanto, Arief, O'sullivan, Kathleen, Staaf, Johan, Borg, Ake, Pawitan, Yudi

Abstract is not available

The Wilms' Tumor Gene 1 (WT1) Induces Expression of the N-myc Downstream Regulated Gene 2 (NDRG2). (2007)

Svensson, Emelie, Vidovic, Karina, Olofsson, Tor, Vallon-Christersson, Johan, Borg, Ake, Gullberg, Urban

Abstract is not available

Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors (2006)

Johannsdottir, Hrefna K, Jonsson, Goran, Johannesdottir, Gudrun, Agnarsson, Bjarni A, Eerola, Hannaleena, Arason, Adalgeir, ...

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RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability. (2006)

Heikkinen, Katri, Rapakko, Katrin, Karppinen, Sanna-Maria, Erkko, Hannele, Knuutila, Sakari, Lundán, Tuija, ...

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CHEK21100delC in patients with metachronous cancers of the breast and the colorectum (2006)

Isinger, Anna, Bhat, Misha, Borg, Ake, Nilbert, Mef

Abstract Background Development of multiple primary tumors is a hallmark of hereditary cancer. At least 1/10 of breast cancers and colorectal cancers occur because of heredity and recently the cell...

p53 mutation and cyclin D1 amplification correlate with cisplatin sensitivity in xenografted human squamous cell carcinomas from head and neck. (2006)

Henriksson, Eva, Baldetorp, Bo, Borg, Ake, Kjellen, Elisabeth, Akervall, Jan, Wennerberg, Johan, ...

Abstract is not available

Differences in IGFBP-3 regulation between young healthy women from BRCAX families and those belonging to BRCA1/2 families. (2006)

Jernstrom, Helena, Sellberg, Gunilla, Borg, Ake, Olsson, Hakan

Abstract is not available

Array-based comparative genomic hybridization characterization of cytogenetically polyclonal myeloid malignancies. (2006)

Davidsson, Josef, Heidenblad, Markus, Borg, Ake, Johansson, Bertil

Abstract is not available.

Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. (2006)

Holmquist-Mengelbier, Linda, Fredlund, Erik, Lofstedt, Tobias, Noguera, Rosa, Navarro, Samuel, Nilsson, Helén, ...

Abstract is not available

Intratumor versus intertumor heterogeneity in gene expression profiles of soft-tissue sarcomas. (2005)

Francis, Princy, Fernebro, Josefin, Edén, Patrik, Laurell, Anna, Rydholm, Anders, Domanski, Henryk A, ...

Abstract is not available

Mapping of a novel ocular and cutaneous malignant melanoma susceptibility locus to chromosome 9q21.32. (2005)

Jönsson, Göran, Bendahl, Pär-Ola, Sandberg, Therese, Kurbasic, Azra, Staaf, Johan, Sunde, Lone, ...

Abstract is not available

Gene expression profiles relate to SS18/SSX fusion type in synovial sarcoma. (2005)

Fernebro, Josefin, Francis, Princy, Edén, Patrik, Borg, Ake, Panagopoulos, Ioannis, Mertens, Fredrik, ...

Abstract is not available

Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization. (2005)

Jönsson, Göran, Naylor, Tara L, Vallon-Christersson, Johan, Staaf, Johan, Huang, Jia, Ward, M Renee, ...

Abstract is not available

The contribution of the hereditary nonpolyposis colorectal cancer syndrome to the development of ovarian cancer. (2005)

Malander, Susanne, Rambech, Eva, Kristoffersson, Ulf, Halvarsson, Britta, Ridderheim, Mona, Borg, Ake, ...

Abstract is not available

Deletions on chromosome 4 in sporadic and BRCA mutated tumors and association with pathological variables (2004)

Johannsdottir, Hrefna K, Johannesdottir, Gudrun, Agnarsson, Bjarni A, Eerola, Hannaleena, Arason, Adalgeir, Johannsson, Oskar T H, ...

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Predicting continuous values of prognostic markers in breast cancer from microarray gene expression profiles. (2004)

Gruvberger-Saal, Sofia K, Edén, Patrik, Ringnér, Markus, Baldetorp, Bo, Chebil, Gunilla, Borg, Ake, ...

Abstract is not available

Human neuroblastoma cells exposed to hypoxia: induction of genes associated with growth, survival, and aggressive behavior. (2004)

Jögi, Annika, Vallon-Christersson, Johan, Holmquist, Linda, Axelson, Håkan, Borg, Ake, Påhlman, Sven

Abstract is not available

Staf50 is a novel p53 target gene conferring reduced clonogenic growth of leukemic U-937 cells. (2004)

Obad, Susanna, Brunnström, Hans, Vallon-Christersson, Johan, Borg, Ake, Drott, Kristina, Gullberg, Urban

Abstract is not available

Characterization of a novel breast carcinoma xenograft and cell line derived from a BRCA1 germ-line mutation carrier (2003)

Johannsson, Oskar T, Staff, Synnöve, Vallon-Christersson, Johan, Kytöla, Soili, Gudjonsson, Thorarinn, Rennstam, Karin, ...

A human tumor xenograft (L56Br-X1) was established from a breast cancer axillary lymph node metastasis of a 53-year-old woman with a BRCA1 germ-line nonsense mutation (1806C>T; Q563X), and a cell...

Predicting the future of breast cancer. (2003)

Borg, Ake, Fernö, Mårten, Peterson, Carsten

Abstract not available.

Characterization of a Novel Breast Carcinoma Xenograft and Cell Line Derived from a BRCA1 Germ-Line Mutation Carrier. (2003)

Johannsson, Oskar T, Staff, Synnöve, Vallon-Christersson, Johan, Kytöla, Soili, Gudjonsson, Thorarinn, Rennstam, Karin, ...

A human tumor xenograft (L56Br-X1) was established from a breast cancer axillary lymph node metastasis of a 53-year-old woman with a BRCA1 germ-line nonsense mutation (1806C>T; Q563X), and a cell...

Patterns of chromosomal imbalances defines subgroups of breast cancer with distinct clinical features and prognosis. A study of 305 tumors by comparative genomic hybridization. (2003)

Rennstam, Karin, Ahlstedt-Soini, Minna, Baldetorp, Bo, Bendahl, Pär-Ola, Borg, Ake, Karhu, Ritva, ...

Abstract is not available

A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes (2002)

Rozenblum, Ester, Vahteristo, Pia, Sandberg, Therese, Bergthorsson, Jon Thor, Syrjakoski, Kirsi, Weaver, Don, ...

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Chromosomal translocations involving 11q13 contribute to cyclin D1 overexpression in squamous cell carcinoma of the head and neck. (2002)

Akervall, Jan, Borg, Ake, Dictor, Michael, Jin, Charlotte, Jin, Yuesheng, Tanner, Minna, ...

CCND1 amplification results in cyclin D1 overexpression. However, other unidentified genetic mechanisms contribute to enhanced gene expression. In the present study, 32 squamous cell carcinoma of the...

Low frequency of E-cadherin alterations in familial breast cancer (2001)

Salahshor, Sima, Haixin, Lei, Huo, Huagang, Kristensen, Vessela N., Loman, Niklas, Sjoberg-Margolin, Sara, ...

In order to explore the possible role of E-cadherin in familial cancer, 19 familial breast cancer patients, whose tumours demonstrated loss of heterozygosity (LOH) at the E-cadherin locus, were...

CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum

Isinger, Anna, Bhat, Misha, Borg, Ake, Nilbert, Mef

CHEK2 1100delC in patients with metachronous cancers of the breast and the colorectum

Isinger, Anna, Bhat, Misha, Borg, Ake, Nilbert, Mef

An Evaluation of Genetic Heterogeneity in 145 Breast-Ovarian Cancer Families

Narod, Steven A., Ford, Deborah, Devilee, Peter, Barkardottir, Rosa B., Lynch, Henry T., Smith, Simon A., ...

The breast-ovary cancer–family syndrome is a dominant predisposition to cancer of the breast and ovaries which has been mapped to chromosome region 17ql2-q21. The majority, but not all, of...