Suzuki, Motoshi, Niimi, Atsuko, Limsirichaikul, Siripan, Tomida, Shuta, Miao Huang, Qin, Izuta, Shunji, ...
Translesion DNA synthesis (TLS) involves PCNA mono-ubiquitination and TLS DNA polymerases (pols). Recent evidence has shown that the mono-ubiquitination is induced not only by DNA damage but also by...
Kikuchi, Akihiko, Okano, Teruo
Biomaterials surface design is critical for control of cell–materials interactions. Materials surface characteristics important to cell–materials interactions are the following: (a) nonfouling...
Suda, Namiko, Ito, Yasutomo, Imai, Tsuneo, Kikumori, Toyone, Kikuchi, Akihiko, Nishiyama, Yukihiro, ...
We introduced a series of Pro substitutions within and near the α4 helix, a part of the breakage/rejoining region, in human DNA topoisomerase IIα, and analyzed if this region is involved in...
Sakaguchi, Ayako, Miyaike, Mitsuko, Kuroda, Kazufumi, Nozaki, Naohito, Tanaka, Masato, Hibino, Makoto, ...
The epitopes of about 100 monoclonal antibodies against human type II DNA topoi-somerase were mapped along the enzyme molecules. Although they were randomly and independently established, epitope...
DNA Topoisomerase: the Key Enzyme that Regulates DNA Super Structure (1998)
Kato, Satoshi, Kikuchi, Akihiko
Nagoya Journal of Medical Science, 61(1-2), 1998, p. 11-26
Adachi, Noritaka, Miyaike, Mitsuko, Ikeda, Hideo, Kikuchi, Akihiko
Several cDNA clones encoding mouse DNA topoisomerase II were obtained from a mouse spermatocyte cDNA library and the entire coding sequence of the gene was determined. The mouse DNA topoisomerase II...
In Vitro Synthesis of Ornithine Transcarbamylase (1978)
DOHI, Michio, INOUYE, Hiroshi, KIKUCHI, Akihiko, GORINI, Luigi
An in vitro system for the synthesis of ornithine transcarbamylase (OTCase) was established using iS-30 extract from E. coli MDS6−2(“) and DNA of a “ transducing phage carrying argI and argF...
Some Regulation Profiles of Ornithine Transcarbamylase Synthesis In Vitro (1978)
DOHI, Michio, KIKUCHI, Akihiko, GORINI, Luigi
The regulation profiles of OTCase (argF, argI) synthesis in vitro were investigated by using the in vitro system described in the accompanying paper. Addition of 2.6 mM arginine, crude repressor and...
Matsumoto, Ken, Nagata, Kyosuke, Miyaji-Yamaguchi, Mary, Kikuchi, Akihiko, Tsujimoto, Masafumi
Template activating factor I (TAF-I) was originally identified as a host factor required for DNA replication and transcription of adenovirus genome complexed with viral basic proteins. Purified TAF-I...
Involvement of Nucleocytoplasmic Shuttling of Yeast Nap1 in Mitotic Progression
Miyaji-Yamaguchi, Mary, Kato, Kohsuke, Nakano, Ryosuke, Akashi, Tomohiro, Kikuchi, Akihiko, Nagata, Kyosuke
Nucleosome assembly protein 1 (Nap1) is widely conserved from yeasts to humans and facilitates nucleosome formation in vitro as a histone chaperone. Nap1 is generally localized in the cytoplasm,...
Suda, Namiko, Ito, Yasutomo, Imai, Tsuneo, Kikumori, Toyone, Kikuchi, Akihiko, Nishiyama, Yukihiro, ...
We introduced a series of Pro substitutions within and near the α4 helix, a part of the breakage/rejoining region, in human DNA topoisomerase IIα, and analyzed if this region is involved in...
Reverse gyrase; ATP-dependent type I topoisomerase from Sulfolobus
Reverse gyrase, a topoisomerase which introduces positive superhelical turns into DNA, has been purified from Sulfolobus to near homogeneity. It is a single polypeptide with a mol. wt. of 120 000 as...
Jalloh, Amadu, Van Thien, Huynh, Ferreira, Marcelo U., Ohashi, Jun, Matsuoka, Hiroyuki, Kanbe, Toshio, ...
In an effort to decipher the nature and extent of antigen polymorphisms of malaria parasites in a setting where malaria is hypomesoendemic, we conducted a 5-year longitudinal study (1998 to 2003) by...
Ohkuni, Kentaro, Okuda, Asuko, Kikuchi, Akihiko
Nbp2p is a Nap1-binding protein in Saccharomyces cerevisiae identified by its interaction with Nap1 by a two-hybrid system. NBP2 encodes a novel protein consisting of 236 amino acids with a Src...
Matsumoto, Ken, Nagata, Kyosuke, Miyaji-Yamaguchi, Mary, Kikuchi, Akihiko, Tsujimoto, Masafumi
Template activating factor I (TAF-I) was originally identified as a host factor required for DNA replication and transcription of adenovirus genome complexed with viral basic proteins. Purified TAF-I...
Involvement of Nucleocytoplasmic Shuttling of Yeast Nap1 in Mitotic Progression
Miyaji-Yamaguchi, Mary, Kato, Kohsuke, Nakano, Ryosuke, Akashi, Tomohiro, Kikuchi, Akihiko, Nagata, Kyosuke
Nucleosome assembly protein 1 (Nap1) is widely conserved from yeasts to humans and facilitates nucleosome formation in vitro as a histone chaperone. Nap1 is generally localized in the cytoplasm,...
Suda, Namiko, Ito, Yasutomo, Imai, Tsuneo, Kikumori, Toyone, Kikuchi, Akihiko, Nishiyama, Yukihiro, ...
We introduced a series of Pro substitutions within and near the α4 helix, a part of the breakage/rejoining region, in human DNA topoisomerase IIα, and analyzed if this region is involved in...
Reverse gyrase; ATP-dependent type I topoisomerase from Sulfolobus
Reverse gyrase, a topoisomerase which introduces positive superhelical turns into DNA, has been purified from Sulfolobus to near homogeneity. It is a single polypeptide with a mol. wt. of 120 000 as...
Jalloh, Amadu, Van Thien, Huynh, Ferreira, Marcelo U., Ohashi, Jun, Matsuoka, Hiroyuki, Kanbe, Toshio, ...
In an effort to decipher the nature and extent of antigen polymorphisms of malaria parasites in a setting where malaria is hypomesoendemic, we conducted a 5-year longitudinal study (1998 to 2003) by...
Ohkuni, Kentaro, Okuda, Asuko, Kikuchi, Akihiko
Nbp2p is a Nap1-binding protein in Saccharomyces cerevisiae identified by its interaction with Nap1 by a two-hybrid system. NBP2 encodes a novel protein consisting of 236 amino acids with a Src...
Meyer, Kay N., Kjeldsen, Eigil, Straub, Tobias, Knudsen, Birgitta R., Hickson, Ian D., Kikuchi, Akihiko, ...
We visualized DNA topoisomerases in A431 cells and isolated chromosomes by isoenzyme-selective immunofluorescence microscopy. In interphase, topoisomerase I mainly had a homogeneous nuclear...
Hosoya, Ken-ichi, Tetsuka, Kazuhiro, Nagase, Katsuhiko, Tomi, Masatoshi, Saeki, Shigeki, Ohtsuki, Sumio, ...
Five immortalized brain capillary endothelial cell lines (TM-BBB1-5) were established from 3 transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene (Tg mouse). These...