In order to investigate the immunological responsiveness of tumor-bearing hosts to tumor cells, splenic suppressor cells from Ehrlich tumor-bearing mice that inhibited anti-tumor effector cell...
Surgical treatment for Crohn's disease. (2007)
Perdomo, Jose Antonio, Iwagaki, Hiromi, Hizuta, Akio, Mizuno, Motowo, Nakagawa, Hitoshi, Tanaka, Noriaki, ...
The medical records of 16 consecutive patients with Crohn's disease surgically treated in our department from 1978 to 1993 were retrospectively reviewed. The indication for surgery was obstructive...
Suo, Jian, Tanaka, Noriaki, Hizuta, Akio, Yunoki, Shigeru, Orita, Kunzo
PSK (Krestin) is a protein-bound polysaccharide with antitumor and immunomodulatory activity. In this study, the effects of the oral administration of PSK were investigated on the natural killer (NK)...
The importance of family study in the patients with familial adenomatous polyposis. (2007)
Perdomo, Jose Antonio, Iwagaki, Hiromi, Hizuta, Akio, Tanaka, Noriaki, Orita, Kunzo
Familial adenomatous polyposis (FAP) is a well-known autosomal dominant disorder characterized by the formation of multiple adenomatous polyps of the colon. Gardner's syndrome is a variant of...
Clinical value of soluble interleukin-2 receptor in infectious complications. (2007)
Iwagaki, Hiromi, Hizuta, Akio, Iwadou, Hironori, Perdomo, Jose Antonio, Tanaka, Noriaki, Orita, Kunzo
In this study, we investigated serum-soluble interleukin-2 receptor (sIL-2r) and neopterin (NPT) levels in five patients with severe postoperative infections. A total of 25 synchronous determinations...
Ariki, Norifumi, Iwagaki, Hiromi, Yoshino, Tadashi, Nonaka, Yasuyuki, Fujiki, Shigeatsu, Perdomo, Jose Antonio, ...
Endoscopical segmental piecemeal tumorectomy (ESPT) for nodular elevation of colorectal tumor is advantageous in terms of minimizing both surgical invasion and postoperative burden to the patients....
Zhang, Wei, Naomoto, Yoshio, Tanaka, Noriaki, Hizuta, Akio, Orita, Kunzo
The effects of the combination of natural human tumor necrosis factor-alpha (nHuTNF-alpha) and natural human interferon-alpha (nHuIFN-alpha) on the induction of apoptosis were investigated by...
Ovarian Metastasis in Patients with Colorectal Carcinoma (2007)
Perdomo, Jose A, Hizuta, Akio, Iwagaki, Hiromi, Takasu, Shinji, Nonaka, Yasuyuki, Kimura, Toshikazu, ...
The records of 159 patients who underwent surgical resection of colorectal cancer were reviewed to assess the incidence of ovarian metastasis and to define the role of oophorectomy. Four of these...
Combined therapy with interleukin 2 and indomethacin in mice inoculated with MH134 hepatoma. (2007)
Tanaka, Noriaki, Okamoto, Yasuhisa, Gotoh, Kiyotoshi, Hizuta, Akio, Yunoki, Shigeru, Orita, Kunzo
The antitumor effects of indomethacin and interleukin 2 (IL-2) were studied in C3H/HeJ mice inoculated with MH134 hepatoma cells. Combined treatment with indomethacin and IL-2 augmented natural...
Cancer cachexia and depressive states: a neuro-endocrine-immunological disease? (2007)
Iwagaki, Hiromi, Hizuta, Akio, Uomoto, Masashi, Takeuchi, Yoshiaki, Saito, Shinya, Tanaka, Noriaki
Plasma 5-hydroxytryptamine (serotonin), tryptophan, neopterin and cortisol levels were measured in patients with depressive cancer cachexia and in healthy controls during the same time period....
Iwagaki, Hiromi, Hizuta, Akio, Fujiwara, Toshiyushi, Perdomo, Jose Antonio, Tanaka, Noriaki, Orita, Kunzo
Patients with far advanced colorectal cancers received chemotherapy consisting of low-dose cyclophosphamide (LDCY) 333 mg/m2 every four weeks intravenously and by oral administration of 5'-DFUR (a...
Enhancement of experimental metastasis by gamma-interferon in a murine adenocarcinoma. (2007)
Hirano, Tetsuo, Hizuta, Akio, Tanaka, Noriaki, Orita, Kunzo
This study was conducted to examine the effect of gamma-interferon (IFN-gamma) on experimental metastasis formation by murine colon 26 adenocarcinoma in BALB/c mice. We found that the number of...
Hyperthermotherapy for postoperative local recurrences of rectal cancer. (2007)
Kuroda, Masahiro, Hizuta, Akio, Iwagaki, Hiromi, Makihata, Eiichi, Asaumi, Junichi, Nishikawa, Koji, ...
Between November 1984 and August 1992 we used hyperthermotherapy in six cases of local recurrence of rectal cancer. Hyperthermotherapy was performed on the average 8.7 times (range: 3-18) for each...
Therapeutic effect of neuraminidase-treated LAK cells on liver metastasis of Colon 26. (2007)
Kamitani, Shingo, Tanaka, Noriaki, Yunoki, Shigeru, Hizuta, Akio, Orita, Kunzo
To improve the lymphokine-activated killer (LAK) cell therapy for liver metastasis, two methods which enhance accumulation of LAK cells in the liver were examined for their effects on the liver...
Occlusion of a postoperative rectoabdominocutaneous fistula with fibrin clot: a case report. (2007)
Iwagaki, Hiromi, Hizuta, Akio, Nezu, Masashi, Nonaka, Yasuyuki, Kimura, Toshikazu, Marutaka, Masahito, ...
A 56 year-old rectal cancer patient who developed a chronic rectoabdominocutaneous fistula postoperatively was treated with fibrin clot, and the fistula healed completely. Occlusion of chronic...
Tanaka, Noriaki, Tatemoto, Akihiko, Urabe, Takamitsu, Ono, Minoru, Hizuta, Akio, Naomoto, Yoshio, ...
Lymphokine activated killer (LAK) cells can destroy not only tumor cells but also syngeneic liver cells. In this study, the effects of passive transfer of LAK cells on liver regeneration were...
Assessment of lymph node metastasis and vessel invasion in early rectal cancer. (2007)
Moreira, Luis Fernando, Iwagaki, Hiromi, Inoguchi, Kazuhito, Hizuta, Akio, Sakagami, Keinichi, Orita, Kunzo
Thirteen patients with rectal carcinoma seen between December 1980 and December 1990 have been reviewed to determine the risk of lymph node metastasis and its implication for subsequent treatment....
Gotohda, Naoto, Iwagaki, Hiromi, Itano, Satoshi, Horiki, Sadayuki, Fujiwara, Toshiya, Saito, Shinya, ...
POSSUM, a Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity, is a scoring system which assesses perioperative surgical risks (Copeland GP et al.: Br J Surg,...