Akio Sakamoto

Establishment of an animal model of a pasteurized bone graft, with a preliminary analysis of muscle coverage or FGF-2 administration to the graft (2009)

Yoshida, Tatsuya, Sakamoto, Akio, Tsukamoto, Nobuaki, Nakayama, Koichi, Iwamoto, Yukihide

Abstract Background Pasteurized bone grafting is used following the excision of a bone tumor for the purpose of eliminating neoplastic cells while preserving bone-inducing ability. In the hopes of...

False aneurysm of the superficial palmar arch in a child: a case report (2009)

Sakamoto, Akio, Arai, Ken

Abstract Introduction False aneurysm of the arteries of the hand is extremely rare. Case presentation We report a case of false aneurysm of the superficial palmar arch in a 4-year-old boy following...

Mutation analysis of the Gadd45 gene at exon 4 in atypical fibroxanthoma (2009)

Sakamoto, Akio, Akieda, Shizuka, Oda, Yoshinao, Iwamoto, Yukihide, Tsuneyoshi, Masazumi

Abstract Background Atypical fibroxanthoma (AFX) histologically mimics high-grade sarcoma in the skin, although it follows a benign clinical course. AFX occurs in the sun-exposed skin and for this...

Epithelioid sarcoma with muscle metastasis detected by positron emission tomography (2008)

Sakamoto, Akio, Jono, Osamu, Hirahashi, Minako, Oya, Masafumi, Iwamoto, Yukihide, Arai, Ken

Abstract Background Epithelioid sarcoma is an uncommon high-grade sarcoma, mostly involving the extremities. Case presentation A 33-year-old man was referred to our institute with a diagnosis of...

Long-term follow-up on the use of vascularized fibular graft for the treatment of congenital pseudarthrosis of the tibia (2008)

Sakamoto, Akio, Yoshida, Tatsuya, Uchida, Yoshio, Kojima, Tetsuo, Kubota, Hideaki, Iwamoto, Yukihide

Abstract Background Congenital pseudoarthrosis of the tibia (CPT) is one of the most difficult conditions to treat. Methods Five girls and 3 boys with CPT were treated by vascularized fibular...

Proceedings of the Third NTCIR Workshop Exploitation of Newspaper-article Characteristics for Article Retrieval and Answer Extraction in QAC Task 2 (2008)

Ruck Thawonmas, Takayuki Tomoike, Tomohiko Kawachi, Akio Sakamoto

In this paper, we discuss a system for newspaper article retrieval and answer extraction. Due to the rapidly increasing amount of accessible information, systems that allow search in natural language...

Atypical Fibroxanthoma (2008)

Akio Sakamoto

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its...

Insufficiency Fracture in the Para-Acetabulum, with Features Mimicking Those of a Malignant Bone Tumor (2008)

Akio Sakamoto, Takuaki Yamamoto, Kazuhiro Tanaka, Shuichi Matsuda, Tatsuya Yoshida, Yukihide Iwamoto

Para-acetabular insufficiency fractures are rare and exceedingly difficult to diagnose without a high index of suspicion, since the images mimic those of bone tumors. We herein present the case of a...

Dedifferentiated liposarcoma with leukocytosis. A case report of G-CSF-producing soft-tissue tumors, possible association with undifferentiated liposarcoma lineage (2007)

Sakamoto, Akio, Matono, Hiroshi, Yoshida, Tatsuya, Tanaka, Kazuhiro, Matsuda, Shuichi, Oda, Yoshinao, ...

Abstract Background Granulocyte-colony-stimulating factor (G-CSF) functions as a hematopoietic growth factor and it is responsible for leukocytosis. G-CSF-producing tumors associated with...

Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features (2007)

Sakamoto, Akio, Yoshida, Tatsuya, Matsuura, Suguru, Tanaka, Kazuhiro, Matsuda, Shuichi, Oda, Yoshinao, ...

Abstract Background The skeletal muscle is an unusual site for metastasis from renal cell carcinoma (RCC). Metastatic RCC must be differentiated from benign primary soft-tissue tumors because...

Dedifferentiated chondrosarcoma with leukocytosis and elevation of serum G-CSF. A case report (2006)

Sakamoto, Akio, Yamamoto, Hidetaka, Tanaka, Kazuhiro, Matsuda, Shuichi, Harimaya, Katsumi, Oda, Yoshinao, ...

Abstract Background G-CSF is known to function as a hematopoietic growth factor and it is known to be responsible for leukocytosis. G-CSF-producing tumors associated with leukocytosis include various...

Tissue-specific imprinting of the G protein Gs{alpha} is associated with tissue-specific differences in histone methylation (2004)

Sakamoto, Akio, Liu, Jie, Greene, Andrew, Chen, Min, Weinstein, Lee S.

The G protein Gsα is imprinted in a tissue-specific manner, being primarily expressed from the maternal allele in some tissues, such as renal proximal tubules. The Gsα promoter is unmethylated, but...

Tissue-specific imprinting of the G protein Gs{alpha} is associated with tissue-specific differences in histone methylation (2004)

Sakamoto, Akio, Liu, Jie, Greene, Andrew, Chen, Min, Weinstein, Lee S.

The G protein Gsα is imprinted in a tissue-specific manner, being primarily expressed from the maternal allele in some tissues, such as renal proximal tubules. The Gsα promoter is unmethylated, but...

Tissue-specific imprinting of the G protein Gs{alpha} is associated with tissue-specific differences in histone methylation (2004)

Sakamoto, Akio, Liu, Jie, Greene, Andrew, Chen, Min, Weinstein, Lee S.

The G protein Gsα is imprinted in a tissue-specific manner, being primarily expressed from the maternal allele in some tissues, such as renal proximal tubules. The Gsα promoter is unmethylated, but...

E-Cadherin Gene Mutations Frequently Occur in Synovial Sarcoma as a Determinant of Histological Features

Saito, Tsuyoshi, Oda, Yoshinao, Sugimachi, Keishi, Kawaguchi, Ken-ichi, Tamiya, Sadafumi, Tanaka, Kazuhiro, ...

Synovial sarcoma is a mesenchymal tumor that has an epithelial character and two major histological subtypes, the biphasic type and the monophasic fibrous type. However, the mechanisms involved in...

A Comparative Study of Fibrous Dysplasia and Osteofibrous Dysplasia with Regard to GSα Mutation at the Arg201 Codon: Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Analysis of Paraffin-Embedded Tissues

Sakamoto, Akio, Oda, Yoshinao, Iwamoto, Yukihide, Tsuneyoshi, Masazumi

Fibrous dysplasia and osteofibrous dysplasia are both benign fibro-osseous lesions of the bone and are generally seen during childhood or adolescence. Histologically, the features of these bone...

Current Status and Perspectives Regarding the Treatment of Osteosarcoma: Chemotherapy

Sakamoto, Akio, Iwamoto, Yukihide

Osteosarcoma is the most common primary bone tumor in childhood and adolescence. The use of combination chemotherapy and surgery enables long-term survival in approximately 60-70% of cases. However,...