Akito Sakai

Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study (2006)

Yamashita, Tatsuya, Arai, Kuniaki, Sakai, Akito, Mizukoshi, Eishiro, Sakai, Yoshio, Kagaya, Takashi, ...

Purpose: In patients with chronic genotype 1b hepatitis C and a high viral load, the viral load was reduced by double filtration plasmapheresis (DFPP), followed by combined interferon and ribavirin...

The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

Sakai, Akito, Claire, Marisa St., Faulk, Kristina, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., ...

The role of the hepatitis C virus (HCV) p7 protein in the virus life cycle is not known. Previous in vitro data indicated that this 63-aa polypeptide is located in the endoplasmic reticulum and has...

Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study

Yamashita, Tatsuya, Arai, Kuniaki, Sakai, Akito, Mizukoshi, Eishiro, Sakai, Yoshio, Kagaya, Takashi, ...

Purpose: In patients with chronic genotype 1b hepatitis C and a high viral load, the viral load was reduced by double filtration plasmapheresis (DFPP), followed by combined interferon and ribavirin...

The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences

Sakai, Akito, Claire, Marisa St., Faulk, Kristina, Govindarajan, Sugantha, Emerson, Suzanne U., Purcell, Robert H., ...

The role of the hepatitis C virus (HCV) p7 protein in the virus life cycle is not known. Previous in vitro data indicated that this 63-aa polypeptide is located in the endoplasmic reticulum and has...

Virological effects and safety of combined double filtration plasmapheresis (DFPP) and interferon therapy in patients with chronic hepatitis C: A preliminary study

Yamashita, Tatsuya, Arai, Kuniaki, Sakai, Akito, Mizukoshi, Eishiro, Sakai, Yoshio, Kagaya, Takashi, ...

Purpose: In patients with chronic genotype 1b hepatitis C and a high viral load, the viral load was reduced by double filtration plasmapheresis (DFPP), followed by combined interferon and ribavirin...

In Vivo Study of the HC-TN Strain of Hepatitis C Virus Recovered from a Patient with Fulminant Hepatitis: RNA Transcripts of a Molecular Clone (pHC-TN) Are Infectious in Chimpanzees but Not in Huh7.5 Cells▿

Sakai, Akito, Takikawa, Shingo, Thimme, Robert, Meunier, Jean-Christophe, Spangenberg, Hans Christian, Govindarajan, Sugantha, ...

Both viral and host factors are thought to influence the pathogenesis of hepatitis C virus (HCV) infection. We studied strain HC-TN (genotype 1a), which caused fulminant hepatic failure in a patient...