Alain Dabdoub

Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases (2009)

Vivancos, Valérie, Chen, Ping, Spassky, Nathalie, Qian, Dong, Dabdoub, Alain, Kelley, Matthew, ...

Abstract Background Wnt proteins play roles in many biological processes, including axon guidance and cell migration. In the mammalian hindbrain, facial branchiomotor (FBM) neurons undergo a striking...

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

Dabdoub, Alain, Puligilla, Chandrakala, Jones, Jennifer M., Fritzsch, Bernd, Cheah, Kathryn S. E., Pevny, Larysa H., ...

Sox2 is a high-mobility transcription factor that is one of the earliest markers of developing inner ear prosensory domains. In humans, mutations in SOX2 cause sensorineural hearing loss and a loss...