Alan A. Woodall

DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

Helbock, Harold J., Beckman, Kenneth B., Shigenaga, Mark K., Walter, Patrick B., Woodall, Alan A., Yeo, Helen C., ...

Oxidative DNA damage is important in aging and the degenerative diseases of aging such as cancer. Estimates commonly rely on measurements of 8-oxo-2′-deoxyguanosine (oxo8dG), an adduct that occurs...

γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications

Christen, Stephan, Woodall, Alan A., Shigenaga, Mark K., Southwell-Keely, Peter T., Duncan, Mark W., Ames, Bruce N.

Peroxynitrite, a powerful mutagenic oxidant and nitrating species, is formed by the near diffusion-limited reaction of ·NO and O2⨪ during activation of phagocytes. Chronic inflammation induced by...

DNA oxidation matters: The HPLC–electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

Helbock, Harold J., Beckman, Kenneth B., Shigenaga, Mark K., Walter, Patrick B., Woodall, Alan A., Yeo, Helen C., ...

Oxidative DNA damage is important in aging and the degenerative diseases of aging such as cancer. Estimates commonly rely on measurements of 8-oxo-2′-deoxyguanosine (oxo8dG), an adduct that occurs...

γ-Tocopherol traps mutagenic electrophiles such as NOx and complements α-tocopherol: Physiological implications

Christen, Stephan, Woodall, Alan A., Shigenaga, Mark K., Southwell-Keely, Peter T., Duncan, Mark W., Ames, Bruce N.

Peroxynitrite, a powerful mutagenic oxidant and nitrating species, is formed by the near diffusion-limited reaction of ·NO and O2⨪ during activation of phagocytes. Chronic inflammation induced by...