24 AUTOMATED 3D ANALYSIS OF LARGE (2009)
Brain Mri Databases, Alan C. Evans
In recent years, the study of gross neuroanatomy and its relationship to behavior and brain function has been reenergized by the advent of imaging techniques and the powerful computational tools with...
Pierre Fiset, Tomás Paus, Thierry Daloze, Gilles Plourde, Pascal Meuret, Vincent Bonhomme, ...
In the present study, we used positron emission tomography to investigate changes in regional cerebral blood flow (rCBF) during a general anesthetic infusion set to produce a gradual transition from...
Gong, Gaolang, He, Yong, Concha, Luis, Lebel, Catherine, Gross, Donald W., Evans, Alan C., ...
The characterization of the topological architecture of complex networks underlying the structural and functional organization of the brain is a basic challenge in neuroscience. However, direct...
Introduction MINC 2.0: A modality independent format for multidimensional medical images (2008)
Robert D. Vincent, Andrew Janke, John G. Sled, Peter Neelin, Alan C. Evans
Moo K Chung, Dalton M Kim, Steven Robbins, Alan C Evans, Richard J Davidson
We correlated face recognition task scores to cortical thickness measurements in a group of autistic subjects. Many previous autism anatomical studies neglect to account for age effect and the...
Behavioral/Systems/Cognitive Genetic Contributions to Human Brain Morphology and Intelligence (2008)
Hugo G. Schnack, Danielle Posthuma, Wim F. Baaré, Clarine Van Oel, ...
Variation in gray matter (GM) and white matter (WM) volume of the adult human brain is primarily genetically determined. Moreover, total brain volume is positively correlated with general...
A Comparative Study of Model-Based Brain MRI Tissue Classification Methods (2008)
Chris A. Cocosco, Alex P. Zijdenbos, Noor Kabani, Alan C. Evans
Abstract. A comparative study of the performance of two different approaches to fully automatic (model-based) brain anatomical MRI tissue classification is presented in this paper. Both simulated and...
Chris A. Cocosco, Alan C. Evans
Introduction: There is a growing need in the research and clinical medical imaging community for Internet-capable tools that facilitate remote data dissemination and interaction. 3-dimensional...
Chen, Zhang J., He, Yong, Rosa-Neto, Pedro, Germann, Jurgen, Evans, Alan C.
Modularity, presumably shaped by evolutionary constraints, underlies the functionality of most complex networks ranged from social to biological networks. However, it remains largely unknown in human...
FDG-PET imaging for the evaluation of antiglioma agents in a rat model (2008)
Assadian, Sarah, Aliaga, Antonio, Del Maestro, Rolando F., Evans, Alan C., Bedell, Barry J.
The increasing development of novel anticancer agents demands parallel advances in the methods used to rapidly assess their therapeutic efficacy (TE) in the preclinical phase. We evaluated the...
Brain Size and Cortical Structure in the Adult Human Brain (2008)
Im, Kiho, Lee, Jong-Min, Lyttelton, Oliver, Kim, Sun Hyung, Evans, Alan C., Kim, Sun I.
We investigated the scale relationship between size and cortical structure of human brains in a large sample of magnetic resonance imaging data. Cortical structure was estimated with several measures...
Chris A. Cocosco, Alan C. Evans
Introduction: There is a growing need in the research and clinical medical imaging community for Internet-capable tools that facilitate remote data dissem-ination and interaction. 3-dimensional (3D)...
MICCAI-2002 1 Automatic Generation of Training Data for Brain Tissue Classification from MRI (2007)
Chris A. Cocosco, Alex P. Zijdenbos, Alan C. Evans
Abstract. A novel fully automatic procedure for brain tissue classification from 3D magnetic resonance head images (MRI) is described. The procedure uses feature space proximity measures, and does...
Keith J. Worsley, Steve Robbins, Tomas Paus, Jonathan Taylor, Jay N. Giedd, Judith L. Rapoport, ...
We present a unified statistical approach to deformation-based morphometry applied to the cortical surface. The cerebral cortex has the topology of a 2D highly convoluted sheet. As the brain develops...
Small-World Anatomical Networks in the Human Brain Revealed by Cortical Thickness from MRI (2007)
He, Yong, Chen, Zhang J., Evans, Alan C.
An important issue in neuroscience is the characterization for the underlying architectures of complex brain networks. However, little is known about the network of anatomical connections in the...
Of Gray Matter, Moo K. Chung, Kim M. Dalton, Li Shen, Alan C. Evans, Richard J. Davidson
representation for cortical surfaces. The WFS representation is a data smoothing technique that provides the explicit smooth functional estimation of unknown cortical boundary as a linear combination...
Small-World Anatomical Networks in the Human Brain Revealed by Cortical Thickness from MRI (2007)
He, Yong, Chen, Zhang J., Evans, Alan C.
An important issue in neuroscience is the characterization for the underlying architectures of complex brain networks. However, little is known about the network of anatomical connections in the...
Small-World Anatomical Networks in the Human Brain Revealed by Cortical Thickness from MRI (2007)
He, Yong, Chen, Zhang J., Evans, Alan C.
An important issue in neuroscience is the characterization for the underlying architectures of complex brain networks. However, little is known about the network of anatomical connections in the...
Spatial patterns of cortical thinning in mild cognitive impairment and Alzheimer’s disease (2006)
Vivek Singh, Howard Chertkow, Jason P. Lerch, Alan C. Evans, Adrienne E. Dorr, Noor Jehan Kabani
Cortical thickness is a more reliable measure of atrophy than volume due to the low variability in the cytoarchitectural structure of the grey matter. However, this more desirable measure of...
Tensor-based cortical morphometry via weighted spherical harmonic representation (2006)
Moo K. Chung, Steve Robbins, Kim M. Dalton, Shubing Wang, Alan C. Evans, Richard J. Davidson
We present a new tensor-based morphometric framework that quantifies cortical shape variations using the local area element. The local area element is obtained from the Riemannian metric tensors,...
Unified Cortical Surface Morphometry and Its Application to Quantifying Amount of Gray Matter (2006)
Moo K. Chung, Moo K. Chung, Kim M. Dalton, Li Shen, Alan C. Evans, Richard J. Davidson
In quantifying the amount of gray matter in a population, voxelbased morphometry (VBM) and cortical thickness analysis are the two most widely used techniques. There are still many unanswered...
Weighted spherical harmonic representation and its application to cortical analysis (2006)
Steven M. Robbins, Moo K. Chung, Moo K. Chung, Li Shen, Li Shen, Kim M. Dalton, ...
Abstract. We present a novel weighted spherical harmonic (SPHARM) representation of cortical surfaces and its application to a cortical thickness analysis in autism. The weighted-SPHARM is a...
Spatial patterns of cortical thinning in mild cognitive impairment and Alzheimer's disease (2006)
Singh, Vivek, Chertkow, Howard, Lerch, Jason P., Evans, Alan C., Dorr, Adrienne E., Kabani, Noor Jehan
Cortical thickness is a more reliable measure of atrophy than volume due to the low variability in the cytoarchitectural structure of the grey matter. However, this more desirable measure of...
Spatial patterns of cortical thinning in mild cognitive impairment and Alzheimer's disease (2006)
Singh, Vivek, Chertkow, Howard, Lerch, Jason P., Evans, Alan C., Dorr, Adrienne E., Kabani, Noor Jehan
Cortical thickness is a more reliable measure of atrophy than volume due to the low variability in the cytoarchitectural structure of the grey matter. However, this more desirable measure of...
Unified statistical approach to cortical thickness analysis (2005)
Moo K. Chung, Steve Robbins, Alan C. Evans
Abstract. This paper presents a unified image processing and analysis framework for cortical thickness in characterizing a clinical population. The emphasis is placed on the development of data...
Mapping Brain-Behavior Partial (2005)
Moo K. Chung, Kim M. Dalton, Daniel J. Kelley, Steven M, Alan C. Evans, Richard J. Davidson, ...
This paper presents a streamlined image analysis framework for correlating behavioral measures to anatomical measures on the cortex and detecting the regions of abnormal brain-behavior correlates. We...
Abstract Tensor-based Cortical Morphometry via Weighted Spherical Harmonic Representation (2005)
Moo K. Chung, Steve Robbins, Kim M. Dalton, Shubing Wang, Alan C. Evans, Richard J. Davidson, ...
We present a new tensor-based morphometric framework that quantifies cortical shape variations via the concept of local area element. The local area element is obtained from the Riemannian metric...
Moo K. Chung, Steve Robbins, Alan C. Evans
We present a unified image processing and analysis framework for cortical thickness in characterizing a clinical population. Due to the convoluted non-Euclidean surface geometry, data smoothing and
Lerch, Jason P., Pruessner, Jens C., Zijdenbos, Alex, Hampel, Harald, Teipel, Stefan J., Evans, Alan C.
Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological changes throughout the brain. Magnetic resonance imaging can be used to investigate the regional distribution...
thickness analysis examined through power analysis and a
Tisserand, Danielle J., Pruessner, Jens C., Hofman, Paul, Evans, Alan C., Jolles, Jelle
Voxel-based morphometry (VBM) was used to examine the relation between age and gray matter density cross-sectionally and to study the association between gray matter density and longitudinal decline...
Lerch, Jason P., Pruessner, Jens C., Zijdenbos, Alex, Hampel, Harald, Teipel, Stefan J., Evans, Alan C.
Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological changes throughout the brain. Magnetic resonance imaging can be used to investigate the regional distribution...
Tisserand, Danielle J., Pruessner, Jens C., Hofman, Paul, Evans, Alan C., Jolles, Jelle
Voxel-based morphometry (VBM) was used to examine the relation between age and gray matter density cross-sectionally and to study the association between gray matter density and longitudinal decline...
Tisserand, Danielle J., Pruessner, Jens C., Hofman, Paul, Evans, Alan C., Jolles, Jelle
Voxel-based morphometry (VBM) was used to examine the relation between age and gray matter density cross-sectionally and to study the association between gray matter density and longitudinal decline...
Lerch, Jason P., Pruessner, Jens C., Zijdenbos, Alex, Hampel, Harald, Teipel, Stefan J., Evans, Alan C.
Alzheimer's disease (AD) is characterized by a heterogeneous distribution of pathological changes throughout the brain. Magnetic resonance imaging can be used to investigate the regional distribution...
Tensor-based brain surface modeling and analysis (2003)
Moo K. Chung, Keith J. Worsley, Steve Robbins, Alan C. Evans
We present a unified computational approach to tensorbased morphometry in detecting the brain surface shape difference between two clinical groups based on magnetic resonance images. Our approach is...
A fully automatic and robust brain MRI tissue classification method (2003)
Chris A. Cocosco, Alex P. Zijdenbos, Alan C. Evans
www.elsevier.com / locate / media
A fully automatic and robust brain MRI tissue classification method (2003)
Chris A. Cocosco, Alex P. Zijdenbos, Alan C. Evans
A novel, fully automatic, adaptive, robust procedure for brain tissue classification from 3D magnetic resonance head images (MRI) is described in this paper. The procedure is adaptive in that it...
Gibby Koldenhof, Schnack Itg, Itulshoffpol He, Baard Wfc, Staal Wg, Viergever Ma, ...
Conventional visualization media such as MRI prints and computer screens are inherently two dimensional, making them incapable of displaying true 3D volume data sets. By applying only transparency or...
Cortical Specialization for Processing First- and Second-order Motion (2003)
Dumoulin, Serge O., Baker, Curtis L., Hess, Robert F., Evans, Alan C.
Distinct mechanisms underlying the visual perception of luminance- (first-order) and contrast-defined (second-order) motion have been proposed from electrophysiological, human psychophysical and...
Vascular surgeons test new treatment for abdominal aneurysms (2002)
Vincent J. Cunningham, Marie-claude Asselin, Er Hammers, Alan C. Evans, Roger N. Gunn
Partial Volume Effects in PET lead to quantitative under and over estimations of the regional concentrations of radioactivity in reconstructed images and corresponding errors in derived functional or...
Pruessner, Jens C., Köhler, Stefan, Crane, Joelle, Pruessner, Marita, Lord, Catherine, Byrne, Andrea, ...
Researchers in clinical and basic neuroscience frequently target structures of the human medial temporal lobe (MTL) for volumetric analysis with magnetic resonance imaging (MRI). In neurodegenerative...
Chris A. Cocosco, Alan C. Evans
Abstract. A powerful, robust, portable, and extensible Java application (JIV) was developed for visualization and side-by-side comparison of multiple 3-dimensional medical image datasets. It works...
Changes in brain activity related to eating chocolate: From pleasure to aversion (2001)
Small, Dana M., Zatorre, Robert J., Dagher, Alain, Evans, Alan C., Jones-Gotman, Marilyn
We performed successive H215O-PET scans on volunteers as they ate chocolate to beyond satiety. Thus, the sensory stimulus and act (eating) were held constant while the reward value of the chocolate...
Automated 3-D Extraction of Inner and Outer Surfaces of Cerebral Cortex from MRI (2000)
David Macdonald, Noor Kabani, David Avis, Alan C. Evans
Automatic computer processing of large multidimensional images such as those produced by magnetic resonance imaging (MRI) is greatly aided by deformable models, which are used to extract, identify,...
Georges Le Goualher, Anne Marie Argenti, Michel Duyme, Dorret I. Boomsma, ...
distances can detect a possible genetic encoding. When applied to real data, this study highlighted genetic constraints on the shape of the central sulcus. We found from 10 pairs of monozygotic twins...
Dumoulin, Serge O., Bittar, Richard G., Kabani, Noor J., Baker, Curtis L., Le Goualher, Georges, Pike, G. Bruce, ...
The location of human area V5 (or MT) has been correlated with the intersection of the ascending limb of the inferior temporal sulcus (ALITS) and the lateral occipital sulcus (LO). This study was...
Animal+insect: Improved cortical structure segmentation (1999)
D. Louis Collins, Alex P. Zijdenbos, Alan C. Evans
Abstract. An algorithm for improved automatic segmentation of gross anatomical structures of the human brain is presented that merges the output of a tissue classification process with gross...
BrainWeb: Online Interface to a 3D MRI Simulated Brain Database (1997)
Chris A. Cocosco, Vasken Kollokian, G. Bruce Pike, Alan C. Evans
Introduction: The increased importance of automated computer techniques for anatomical brain mapping from MR images and quantitative brain image analysis methods leads to an increased need for...
BrainWeb: Online Interface to a 3D MRI Simulated Brain Database (1997)
Chris A. Cocosco, Vasken Kollokian, Alan C. Evans
Introduction The increased importance of automated computer techniques for anatomical brain mapping from MR images and quantitative brain image analysis methods leads to an increased need for...
An Extensible MRI Simulator for Post-Processing Evaluation (1996)
Remi Kwan, Alan C. Evans, G. Bruce Pike
. An extensible object-oriented MRI simulation system is presented. This simulator uses first-principle modelling based on the Bloch equations to implement a discrete-event simulation of NMR signal...
Paus, Tomás, Tomaiuolo, Francesco, Otaky, Naim, MacDonald, David, Petrides, Michael, Atlas, Jason, ...
Recent advances in functional neuroimaging of the human cerebral cortex revived interest in the study of the cortical morphology at both macro- and microscopic levels. By means of high-resolution...
PET Studies of Phonetic Processing of Speech: Review, Replication, and Reanalysis (1996)
Zatorre, Robert J., Meyer, Ernst, Gjedde, Albert, Evans, Alan C.
Positron emission tomography was used to investigate cerebral blood flow (CBF) changes associated with the processing of speech. In a first experiment, normal right-handed volunteers were scanned...
Owen, Adrian M., Evans, Alan C., Petrides, Michael
Previous work in nonhuman primates and in patients with frontal lobe damage has suggested that the frontal cortex plays a critical rolein the performance of both spatial and nonspatial working memory...
Detecting and estimating the regions of activation in CBF activation studies in human brain (1993)
Keith J. Worsley, Alan C. Evans, Sean Marrett, Peter Neelin
This paper has proposed a test for regions of activation based on the maximum value. It suffers from the same problem of over-correction as all tests, such as a Bonferroni-corrected test, which...
Petitto, Laura Ann, Zatorre, Robert J., Gauna, Kristine, Nikelski, E. J., Dostie, Deanna, Evans, Alan C.
For more than a century we have understood that our brain's left hemisphere is the primary site for processing language, yet why this is so has remained more elusive. Using positron emission...
Functional anatomy of musical processing in listeners with absolute pitch and relative pitch
Zatorre, Robert J., Perry, David W., Beckett, Christine A., Westbury, Christopher F., Evans, Alan C.
We used both structural and functional brain imaging techniques to investigate the neural basis of absolute pitch (AP), a specialized skill present in some musicians. By using positron emission...
Petitto, Laura Ann, Zatorre, Robert J., Gauna, Kristine, Nikelski, E. J., Dostie, Deanna, Evans, Alan C.
For more than a century we have understood that our brain's left hemisphere is the primary site for processing language, yet why this is so has remained more elusive. Using positron emission...
Functional anatomy of musical processing in listeners with absolute pitch and relative pitch
Zatorre, Robert J., Perry, David W., Beckett, Christine A., Westbury, Christopher F., Evans, Alan C.
We used both structural and functional brain imaging techniques to investigate the neural basis of absolute pitch (AP), a specialized skill present in some musicians. By using positron emission...
Comparing functional connectivity via thresholding correlations and singular value decomposition
Worsley, Keith J, Chen, Jen-I, Lerch, Jason, Evans, Alan C
We compare two common methods for detecting functional connectivity: thresholding correlations and singular value decomposition (SVD). We find that thresholding correlations are better at detecting...
Uncovering Intrinsic Modular Organization of Spontaneous Brain Activity in Humans
He, Yong, Wang, Jinhui, Wang, Liang, Chen, Zhang J., Yan, Chaogan, Yang, Hong, ...
The characterization of topological architecture of complex brain networks is one of the most challenging issues in neuroscience. Slow (
FDG-PET imaging for the evaluation of antiglioma agents in a rat model
Assadian, Sarah, Aliaga, Antonio, Del Maestro, Rolando F., Evans, Alan C., Bedell, Barry J.
The increasing development of novel anticancer agents demands parallel advances in the methods used to rapidly assess their therapeutic efficacy (TE) in the preclinical phase. We evaluated the...
Chen, Zhang J., He, Yong, Rosa-Neto, Pedro, Germann, Jurgen, Evans, Alan C.
Modularity, presumably shaped by evolutionary constraints, underlies the functionality of most complex networks ranged from social to biological networks. However, it remains largely unknown in human...