Alan J. Hunt

Centrosome misorientation reduces stem cell division during ageing (2008)

Cheng, Jun, Turkel, Nezaket, Hemati, Nahid, Fuller, Margaret T., Hunt, Alan J., Yamashita, Yukiko M.

Asymmetric division of adult stem cells generates one self- renewing stem cell and one differentiating cell, thereby maintaining tissue homeostasis. A decline in stem cell function has been proposed...

A Theoretical Model of a Molecular-Motor-Powered Pump (2005)

Bull, Joseph L., Hunt, Alan J., Meyhöfer, Edgar

The motion of a cylindrical bead in a fluid contained within a two-dimensional channel is investigated using the boundary element method as a model of a biomolecular-motor-powered microfluidics pump....

Micropatterned Structures for Studying the Mechanics of Biological Polymers (2005)

Schek, Henry T., Hunt, Alan J.

Studying the mechanics of nanometer-scale biomolecules presents many challenges; these include maintaining light microscopy image quality and avoiding interference with the laser used for mechanical...

Nanoscale protein patterning by imprint lithography (2004)

J. Damon Hoff, Li-jing Cheng, Edgar Meyhofer, L. Jay Guo, Alan J. Hunt

Selective localization of active proteins to patterns or specific sites is important for development of biosensors, bioMEMS, tissue engineering, and basic proteomic research. We present a flexible...

ACKNOWLEDGMENTS (2004)

Jindan Yu, Including Drs An, Alan J. Hunt, Tom M. Glaser, Alfred O. Hero, J. Akerley, ...

Transcript profiling of the cone-only Nrl-knockout retina using custom cDNAmicroarrays: identification of novel targets of Nrl and of signaling pathways involved in photoreceptor function

The Dynamic Behavior of Individual Microtubules Associated with Chromosomes In Vitro

Hunt, Alan J., McIntosh, J. Richard

Mitotic movements of chromosomes are usually coupled to the elongation and shortening of the microtubules to which they are bound. The lengths of kinetochore-associated microtubules change by...

Optics at critical intensity: Applications to nanomorphing

Joglekar, Ajit P., Liu, Hsiao-hua, Meyhöfer, Edgar, Mourou, Gerard, Hunt, Alan J.

Laser-induced optical breakdown by femtosecond pulses is extraordinarily precise when the energy is near threshold. Despite numerous applications, the basis for this deterministic nature has not been...

Microtubule movements on the arms of mitotic chromosomes: Polar ejection forces quantified in vitro

Brouhard, Gary J., Hunt, Alan J.

During mitosis, “polar ejection forces” (PEFs) are hypothesized to direct prometaphase chromosome movements by pushing chromosome arms toward the spindle equator. PEFs are postulated to be caused...

A simple, mechanistic model for directional instability during mitotic chromosome movements.

Joglekar, Ajit P, Hunt, Alan J

During mitosis, chromosomes become attached to microtubules that emanate from the two spindle poles. Thereafter, a chromosome moves along these microtubule "tracks" as it executes a series of...

The Dynamic Behavior of Individual Microtubules Associated with Chromosomes In Vitro

Hunt, Alan J., McIntosh, J. Richard

Mitotic movements of chromosomes are usually coupled to the elongation and shortening of the microtubules to which they are bound. The lengths of kinetochore-associated microtubules change by...

Optics at critical intensity: Applications to nanomorphing

Joglekar, Ajit P., Liu, Hsiao-hua, Meyhöfer, Edgar, Mourou, Gerard, Hunt, Alan J.

Laser-induced optical breakdown by femtosecond pulses is extraordinarily precise when the energy is near threshold. Despite numerous applications, the basis for this deterministic nature has not been...

Microtubule movements on the arms of mitotic chromosomes: Polar ejection forces quantified in vitro

Brouhard, Gary J., Hunt, Alan J.

During mitosis, “polar ejection forces” (PEFs) are hypothesized to direct prometaphase chromosome movements by pushing chromosome arms toward the spindle equator. PEFs are postulated to be caused...

A simple, mechanistic model for directional instability during mitotic chromosome movements.

Joglekar, Ajit P, Hunt, Alan J

During mitosis, chromosomes become attached to microtubules that emanate from the two spindle poles. Thereafter, a chromosome moves along these microtubule "tracks" as it executes a series of...

Activation of the MKK/ERK Pathway during Somatic Cell Mitosis: Direct Interactions of Active ERK with Kinetochores and Regulation of the Mitotic 3F3/2 Phosphoantigen

Shapiro, Paul S., Vaisberg, Eugeni, Hunt, Alan J., Tolwinski, Nicholas S., Whalen, Anne M., McIntosh, J. Richard, ...

The mitogen-activated protein (MAP) kinase pathway, which includes extracellular signal–regulated protein kinases 1 and 2 (ERK1, ERK2) and MAP kinase kinases 1 and 2 (MKK1, MKK2), is well-known to...