Alan J. Mears

Publication List Details

Period

1995 - 2005

Number

16

Co-Authors

Reprints (2005)

Masayuki Akimoto, Hong Cheng, Dongxiao Zhu, Joseph A. Brzezinski, Ritu Khanna, ...

doi:10.1073/pnas.0508214103 This information is current as of June 2007. High-resolution figures, a citation map, links to PubMed and Google Scholar, etc., can be found at:...

Multicriteria Gene Screening for Analysis of Differential Expression with DNA Microarrays (2004)

Alfred O. Hero, Gilles Fleury, Alan J. Mears, Anand Swaroop

This paper introduces a statistical methodology for the identification of differentially expressed genes in DNA microarray experiments based on multiple criteria. These criteria are false discovery...

Multicriteria gene screening for analysis of differential expression with DNA microarrays (2004)

Alfred O. Hero, Gilles Fleury, Alan J. Mears, Service Des Mesures, Depts Of Ophthalmology, Visual Sciences, ...

Abstract £ This paper introduces a statistical methodology for identification of differentially expressed genes in DNA microarray experiments based on multiple criteria. These criteria are: false...

Multicriteria Gene Screening for Analysis of Differential Expression with DNA Microarrays (2004)

Anand Swaroop, Alan J. Mears, Gilles Fleury, Alfred O. Hero

This paper introduces a statistical methodology for the identification of differentially expressed genes in DNA microarray experiments based on multiple criteria. These criteria are false discovery...

Multicriteria Gene Screening for Analysis of Differential Expression with DNA Microarrays (2004)

Alfred O. Hero, Gilles Fleury, Alan J. Mears, Anand Swaroop

This paper introduces a statistical methodology for the identification of differentially expressed genes in DNA microarray experiments based on multiple criteria. These criteria are false discovery...

Expression profiling of the developing and mature Nrl-/- mouse retina: Identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Expression profiling of the developing and mature Nrl-/- mouse retina: Identification of retinal disease candidates and transcriptional regulatory targets of Nrl (2004)

Yoshida, Shigeo, Mears, Alan J., Friedman, James S., Carter, Todd, He, Shirley, Oh, Edwin, ...

The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account...

Molecular characterization of duplications associated with cat eye syndrome / (1995)

Mears, Alan J. (Alan Jeffrey)

Submitted to the Faculty of Graduate Studies and Research in partial fulfilment of the requirements for the degree of Doctor of Philosophy, Department of Genetics.

Remapping of the RP15 Locus for X-Linked Cone-Rod Degeneration to Xp11.4-p21.1, and Identification of a De Novo Insertion in the RPGR Exon ORF15

Mears, Alan J., Hiriyanna, Suja, Vervoort, Raf, Yashar, Beverly, Gieser, Linn, Fahrner, Stacey, ...

X-linked forms of retinitis pigmentosa (XLRP) are among the most severe, because of their early onset, often leading to significant vision loss before the 4th decade. Previously, the RP15 locus was...

Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors

Akimoto, Masayuki, Cheng, Hong, Zhu, Dongxiao, Brzezinski, Joseph A., Khanna, Ritu, Filippova, Elena, ...

The Maf-family transcription factor Nrl is a key regulator of photoreceptor differentiation in mammals. Ablation of the Nrl gene in mice leads to functional cones at the expense of rods. We show that...

A Comprehensive Mutation Analysis of RP2 and RPGR in a North American Cohort of Families with X-Linked Retinitis Pigmentosa

Breuer, Debra K., Yashar, Beverly M., Filippova, Elena, Hiriyanna, Suja, Lyons, Robert H., Mears, Alan J., ...

X-linked retinitis pigmentosa (XLRP) is a clinically and genetically heterogeneous degenerative disease of the retina. At least five loci have been mapped for XLRP; of these, RP2 and RP3 account for...

Remapping of the RP15 Locus for X-Linked Cone-Rod Degeneration to Xp11.4-p21.1, and Identification of a De Novo Insertion in the RPGR Exon ORF15

Mears, Alan J., Hiriyanna, Suja, Vervoort, Raf, Yashar, Beverly, Gieser, Linn, Fahrner, Stacey, ...

X-linked forms of retinitis pigmentosa (XLRP) are among the most severe, because of their early onset, often leading to significant vision loss before the 4th decade. Previously, the RP15 locus was...

Targeting of GFP to newborn rods by Nrl promoter and temporal expression profiling of flow-sorted photoreceptors

Akimoto, Masayuki, Cheng, Hong, Zhu, Dongxiao, Brzezinski, Joseph A., Khanna, Ritu, Filippova, Elena, ...

The Maf-family transcription factor Nrl is a key regulator of photoreceptor differentiation in mammals. Ablation of the Nrl gene in mice leads to functional cones at the expense of rods. We show that...

Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity

Wall, Dana S., Mears, Alan J., McNeill, Brian, Mazerolle, Chantal, Thurig, Sherry, Wang, Yaping, ...

Sonic hedgehog (Shh) is an indispensable, extrinsic cue that regulates progenitor and stem cell behavior in the developing and adult mammalian central nervous system. Here, we investigate the link...