Alasdair Ivens

Dictyosteliumtranscriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains (2008)

Carilla-Latorre, Sergio, Calvo-Garrido, Javier, Bloomfield, Gareth, Skelton, Jason, Kay, Robert R, Ivens, Alasdair, ...

Abstract Background Pseudomonas aeruginosa is one of the most relevant human opportunistic bacterial pathogens. Two strains (PAO1 and PA14) have been mainly used as models for studying virulence of...

Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common and specific effects from PAO1 and PA14 strains (2008)

Carilla Latorre, Sergio, Calvo Garrido, Javier, Bloomfield, Gareth, Skelton, Jason, Kay, Robert R., Ivens, Alasdair, ...

15 pages.-- Final full-text version of the paper also available at: http://dx.doi.org/10.1186/1471-2180-8-109.-- Includes 3 additional files: Dictyostelium_s1.xls: Microsoft excel document containing...

Genome-wide transcriptional changes induced by phagocytosis or growth on bacteria in Dictyostelium (2008)

Sillo, Alessio, Bloomfield, Gareth, Balest, Alessandra, Balbo, Alessandra, Pergolizzi, Barbara, Peracino, Barbara, ...

Abstract Background Phagocytosis plays a major role in the defense of higher organisms against microbial infection and provides also the basis for antigen processing in the immune response. Cells of...

Widespread duplications in the genomes of laboratory stocks of Dictyostelium discoideum (2008)

Bloomfield, Gareth, Tanaka, Yoshimasa, Skelton, Jason, Ivens, Alasdair, Kay, Robert R

Abstract Background Duplications of stretches of the genome are an important source of individual genetic variation, but their unrecognized presence in laboratory organisms would be a confounding...

A software framework for microarray and gene expression object model (MAGE-OM) array design annotation (2008)

Qureshi, Matloob, Ivens, Alasdair

Abstract Background The MIAME and MAGE-OM standards defined by the MGED society provide a specification and implementation of a software infrastructure to facilitate the submission and sharing of...

Epigenetic Silencing of Plasmodium falciparum Genes Linked to Erythrocyte Invasion (2007)

Alfred Cortés, Celine Carret, Osamu Kaneko, Alasdair Ivens, Anthony A. Holder

The process of erythrocyte invasion by merozoites of Plasmodium falciparum involves multiple steps, including the formation of a moving junction between parasite and host cell, and it is...

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

Myler, Peter J., Audleman, Lindsey, DeVos, Theo, Hixson, Greg, Kiser, Patti, Lemley, Craig, ...

Leishmania are evolutionarily ancient protozoans (Kinetoplastidae) and important human pathogens that cause a spectrum of diseases ranging from the asymptomatic to the lethal. The Leishmania genome...

Leishmania major Friedlin chromosome 1 has an unusual distribution of protein-coding genes

Myler, Peter J., Audleman, Lindsey, DeVos, Theo, Hixson, Greg, Kiser, Patti, Lemley, Craig, ...

Leishmania are evolutionarily ancient protozoans (Kinetoplastidae) and important human pathogens that cause a spectrum of diseases ranging from the asymptomatic to the lethal. The Leishmania genome...

From genomes to vaccines: Leishmania as a model.

Almeida, Renata, Norrish, Alan, Levick, Mark, Vetrie, David, Freeman, Tom, Vilo, Jaak, ...

The 35 Mb genome of Leishmania should be sequenced by late 2002. It contains approximately 8500 genes that will probably translate into more than 10 000 proteins. In the laboratory we have been...

Epigenetic Silencing of Plasmodium falciparum Genes Linked to Erythrocyte Invasion

Cortés, Alfred, Carret, Celine, Kaneko, Osamu, Ivens, Alasdair, Holder, Anthony A

The process of erythrocyte invasion by merozoites of Plasmodium falciparum involves multiple steps, including the formation of a moving junction between parasite and host cell, and it is...

Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization

Ling, King-Hwa, Rajandream, Marie-Adele, Rivailler, Pierre, Ivens, Alasdair, Yap, Soon-Joo, ...

Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same...

Prophage Sequences Defining Hot Spots of Genome Variation in Salmonella enterica Serovar Typhimurium Can Be Used To Discriminate between Field Isolates▿

Cooke, Fiona J., Wain, John, Fookes, Maria, Ivens, Alasdair, Thomson, Nicholas, Brown, Derek J., ...

Sixty-one Salmonella enterica serovar Typhimurium isolates of animal and human origin, matched by phage type, antimicrobial resistance pattern, and place of isolation, were analyzed by...

Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes

Sebaihia, Mohammed, Peck, Michael W., Minton, Nigel P., Thomson, Nicholas R., Holden, Matthew T.G., Mitchell, Wilfrid J., ...

Clostridium botulinum is a heterogeneous Gram-positive species that comprises four genetically and physiologically distinct groups of bacteria that share the ability to produce botulinum neurotoxin,...

Genome-wide discovery and verification of novel structured RNAs in Plasmodium falciparum

Mourier, Tobias, Carret, Celine, Kyes, Sue, Christodoulou, Zoe, Gardner, Paul P., Jeffares, Daniel C., ...

We undertook a genome-wide search for novel noncoding RNAs (ncRNA) in the malaria parasite Plasmodium falciparum. We used the RNAz program to predict structures in the noncoding regions of the P....