Albert J. Courey

Publication List Details

Period

1986 - 2005

Number

28

Co-Authors

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response (2005)

Song, Haiyun, Nie, Minghua, Qiao, Feng, Bowie, James U., Courey, Albert J.

Phosphorylation of Yan, a major target of Ras signaling, leads to Crm1-dependent Yan nuclear export, a response that is regulated by Yan polymerization. Yan SAM (sterile α motif) domain mutations...

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response (2005)

Song, Haiyun, Nie, Minghua, Qiao, Feng, Bowie, James U., Courey, Albert J.

Phosphorylation of Yan, a major target of Ras signaling, leads to Crm1-dependent Yan nuclear export, a response that is regulated by Yan polymerization. Yan SAM (sterile α motif) domain mutations...

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response (2005)

Song, Haiyun, Nie, Minghua, Qiao, Feng, Bowie, James U., Courey, Albert J.

Phosphorylation of Yan, a major target of Ras signaling, leads to Crm1-dependent Yan nuclear export, a response that is regulated by Yan polymerization. Yan SAM (sterile α motif) domain mutations...

Analysis of Groucho-histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression (2000)

Flores-Saaib, Rubén D., Courey, Albert J.

The Drosophila Groucho (Gro) protein is the defining member of a family of metazoan corepressors that have roles in many aspects of development, including segmentation, dorsal/ventral pattern...

Dorsal-Mediated Repression Requires the Formation of a Multiprotein Repression Complex at the Ventral Silencer

Valentine, Scott A., Chen, Guoqing, Shandala, Tatiana, Fernandez, Joseph, Mische, Sheenah, Saint, Robert, ...

Dorsal functions as both an activator and repressor of transcription to determine dorsoventral fate in the Drosophila melanogaster embryo. Repression by Dorsal requires the corepressor Groucho (Gro)...

A Role for Groucho Tetramerization in Transcriptional Repression

Chen, Guoqing, Nguyen, Pierre H., Courey, Albert J.

The Drosophila Groucho (Gro) protein is a corepressor required by a number of DNA-binding transcriptional repressors. Comparison of Gro with its homologues in other eukaryotic organisms reveals that...

Analysis of Groucho–histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression

Flores-Saaib, Rubén D., Courey, Albert J.

The Drosophila Groucho (Gro) protein is the defining member of a family of metazoan corepressors that have roles in many aspects of development, including segmentation, dorsal/ventral pattern...

Conjugation of Smt3 to Dorsal May Potentiate the Drosophila Immune Response

Bhaskar, Vinay, Smith, Matthew, Courey, Albert J.

A variety of transcription factors are targets for conjugation to the ubiquitin-like protein Smt3 (also called SUMO). While many such factors exhibit enhanced activity under conditions that favor...

The Dorsal Rel Homology Domain Plays an Active Role in Transcriptional Regulation

Jia, Songtao, Flores-Saaib, Rubén D., Courey, Albert J.

The Dorsal morphogen directs formation of the Drosophila dorsoventral axis by both activating and repressing transcription. It contains an N-terminal Rel homology domain (RHD), which is responsible...

Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho

Dubnicoff, Todd, Valentine, Scott A., Chen, Guoqing, Shi, Tao, Lengyel, Judith A., Paroush, Ze’ev, ...

The Dorsal morphogen acts as both an activator and a repressor of transcription in the Drosophila embryo to regulate the expression of dorsal/ventral patterning genes. Circumstantial evidence has...

A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development

Chen, Guoqing, Fernandez, Joseph, Mische, Sheenah, Courey, Albert J.

The Drosophila gene groucho (gro) encodes a transcriptional corepressor that has critical roles in many development processes. In an effort to illuminate the mechanism of Gro-mediated repression, we...

Groucho Oligomerization Is Required for Repression In Vivo

Song, Haiyun, Hasson, Peleg, Paroush, Ze’ev, Courey, Albert J.

Drosophila Groucho (Gro) is a member of a family of metazoan corepressors with widespread roles in development. Previous studies indicated that a conserved domain in Gro, termed the Q domain, was...

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response

Song, Haiyun, Nie, Minghua, Qiao, Feng, Bowie, James U., Courey, Albert J.

Phosphorylation of Yan, a major target of Ras signaling, leads to Crm1-dependent Yan nuclear export, a response that is regulated by Yan polymerization. Yan SAM (sterile α motif) domain mutations...

Dorsal-Mediated Repression Requires the Formation of a Multiprotein Repression Complex at the Ventral Silencer

Valentine, Scott A., Chen, Guoqing, Shandala, Tatiana, Fernandez, Joseph, Mische, Sheenah, Saint, Robert, ...

Dorsal functions as both an activator and repressor of transcription to determine dorsoventral fate in the Drosophila melanogaster embryo. Repression by Dorsal requires the corepressor Groucho (Gro)...

A Role for Groucho Tetramerization in Transcriptional Repression

Chen, Guoqing, Nguyen, Pierre H., Courey, Albert J.

The Drosophila Groucho (Gro) protein is a corepressor required by a number of DNA-binding transcriptional repressors. Comparison of Gro with its homologues in other eukaryotic organisms reveals that...

Analysis of Groucho–histone interactions suggests mechanistic similarities between Groucho- and Tup1-mediated repression

Flores-Saaib, Rubén D., Courey, Albert J.

The Drosophila Groucho (Gro) protein is the defining member of a family of metazoan corepressors that have roles in many aspects of development, including segmentation, dorsal/ventral pattern...

Conjugation of Smt3 to Dorsal May Potentiate the Drosophila Immune Response

Bhaskar, Vinay, Smith, Matthew, Courey, Albert J.

A variety of transcription factors are targets for conjugation to the ubiquitin-like protein Smt3 (also called SUMO). While many such factors exhibit enhanced activity under conditions that favor...

The Dorsal Rel Homology Domain Plays an Active Role in Transcriptional Regulation

Jia, Songtao, Flores-Saaib, Rubén D., Courey, Albert J.

The Dorsal morphogen directs formation of the Drosophila dorsoventral axis by both activating and repressing transcription. It contains an N-terminal Rel homology domain (RHD), which is responsible...

Conversion of Dorsal from an activator to a repressor by the global corepressor Groucho

Dubnicoff, Todd, Valentine, Scott A., Chen, Guoqing, Shi, Tao, Lengyel, Judith A., Paroush, Ze’ev, ...

The Dorsal morphogen acts as both an activator and a repressor of transcription in the Drosophila embryo to regulate the expression of dorsal/ventral patterning genes. Circumstantial evidence has...

A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila development

Chen, Guoqing, Fernandez, Joseph, Mische, Sheenah, Courey, Albert J.

The Drosophila gene groucho (gro) encodes a transcriptional corepressor that has critical roles in many development processes. In an effort to illuminate the mechanism of Gro-mediated repression, we...

Groucho Oligomerization Is Required for Repression In Vivo

Song, Haiyun, Hasson, Peleg, Paroush, Ze’ev, Courey, Albert J.

Drosophila Groucho (Gro) is a member of a family of metazoan corepressors with widespread roles in development. Previous studies indicated that a conserved domain in Gro, termed the Q domain, was...

Antagonistic regulation of Yan nuclear export by Mae and Crm1 may increase the stringency of the Ras response

Song, Haiyun, Nie, Minghua, Qiao, Feng, Bowie, James U., Courey, Albert J.

Phosphorylation of Yan, a major target of Ras signaling, leads to Crm1-dependent Yan nuclear export, a response that is regulated by Yan polymerization. Yan SAM (sterile α motif) domain mutations...

Mae inhibits Pointed-P2 transcriptional activity by blocking its MAPK docking site

Qiao, Feng, Harada, Bryan, Song, Haiyun, Whitelegge, Julian, Courey, Albert J, Bowie, James U

During Drosophila melanogaster eye development, signaling through receptor tyrosine kinases (RTKs) leads to activation of a mitogen activated protein tyrosine kinase, called Rolled. Key nuclear...

Genetic and Proteomic Evidence for Roles of Drosophila SUMO in Cell Cycle Control, Ras Signaling, and Early Pattern Formation

Nie, Minghua, Xie, Yongming, Loo, Joseph A., Courey, Albert J.

SUMO is a protein modifier that is vital for multicellular development. Here we present the first system-wide analysis, combining multiple approaches, to correlate the sumoylated proteome (SUMO-ome)...