Albert Mellick

Inhibitory Effects Associated with Use of Modified Photinus pyralis and Renilla reniformis Luciferase Vectors in Dual Reporter Assays and Implications for Analysis of ISGs. (2005)

Ghazawi, I., Cutler, S., Low, Pauline, Mellick, Albert, Ralph, Stephen John

Luciferase reporter constructs are widely used for analysis of gene regulation when characterizing promoter and enhancer elements. We report that the recently developed codon-modified Renilla...

An examination of MS candidate genes identified as differentially regulated in multiple sclerosis plaque tissue, using absolute and comparative real-time Q-PCR analysis. (2005)

Tajouri, Lotfi, Mellick, Albert, Tourtellotte, A., Nagra, R. M., Griffiths, Lyn

We have developed methods in real time detection of quantitative-polymerase chain reaction (Q-PCR) to analyse the relative levels of gene expression in post mortem brain tissue. We have then examined...

Age-related changes in cardiac adenosine receptor expression (2004)

Jenner, Tamsin, Mellick, Albert, Harrison, Glenn, Griffiths, Lyn, Rose'Meyer, Roselyn

Adenosine is an important cardioprotective agent that works via several adenosine receptor (ADOR) subtypes to regulate cardiovascular activity. It is well established that functional responses to...

Quantitative and qualitative changes in gene expression patterns characterize the activity of plaques in multiple sclerosis (2003)

Tajouri, Lotfi, Mellick, Albert, Ashton, Kevin John, Tannenberg, Anthony E.G., Nagra, Rashed M., Tourtellotte, Wallace W., ...

Multiple sclerosis (MS) is a complex autoimmune disorder of the CNS with both genetic and environmental contributing factors. Clinical symptoms are broadly characterized by initial onset, and...

An Assessment of MMP and TIMP Gene Expression in Cell Lines and Stroma - Tumour Differences in Microdissected Breast Cancer Biopsies (2003)

Mellick, Albert, Blackmore, Daneia, Weinstein, Stephen R., Griffiths, Lyn

To examine matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) mRNA levels in archival breast cancer biopsies, we employed microdissection to separate tumour tissue from...

The measurement of adenosine and estrogen receptor expression in rat brains following ovariectomy using quantitative PCR analysis (2003)

Rose'Meyer, Roselyn, Mellick, Albert, Garnham, Bronwyn Gaye, Harrison, Glenn, Massa, Helen Maureen, Griffiths, Lyn

In our laboratory we have developed a quantitative-polymerase chain reaction (Q-PCR) strategy to examine the differential expression of adenosine receptor (ADOR), A1, A2A, A2B and A3, and estrogen...

Differential Gene Expression in Breast Cancer Cell Lines and Stroma-Tumour Differences in Microdissected Breast Cancer Biopsies Revealed by Display Array Analysis (2002)

Mellick, Albert, Day, Chris, Weinstein, S.R., Griffiths, Lyn, Morrison, Nigel Alexander

To examine gene-expression patterning in late-stage breast cancer biopsies, we used a microdissection technique to separate tumor from the surrounding breast tissue or stroma. A DD-PCR protocol was...

The effects of ovariectomy on the expression of estrogen and adenosine receptors in the rat bladder. (2002)

Owen, Suzzanne, Mellick, Albert, Garnham, Bronwyn Gaye, Griffiths, Lyn, Massa, Helen Maureen, Rose'Meyer, Roselyn

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