Aldert Bart

The reach of the genome signature in prokaryotes (2006)

Van Passel, Mark WJ, Kuramae, Eiko E, Luyf, Angela CM, Bart, Aldert, Boekhout, Teun

Abstract Background With the increased availability of sequenced genomes there have been several initiatives to infer evolutionary relationships by whole genome characteristics. One of these studies...

Compositional discordance between prokaryotic plasmids and host chromosomes (2006)

Van Passel, Mark WJ, Bart, Aldert, Luyf, Angela CM, Van Kampen, Antoine HC, Van Der Ende, Arie

Abstract Background Most plasmids depend on the host replication machinery and possess partitioning genes. These properties confine plasmids to a limited range of hosts, yielding a close and...

Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit (2006)

Al Naiemi, Nashwan, Heddema, Edou R., Bart, Aldert, De Jonge, Evert, Vandenbroucke-Grauls, Christina M., Savelkoul, Paul H. M., ...

Objectives: During treatment with selective decontamination of the digestive tract (SDD), four multidrug-resistant (MDR) strains, three different Escherichia coli and one Klebsiella pneumoniae, were...

Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit (2006)

Al Naiemi, Nashwan, Heddema, Edou R., Bart, Aldert, De Jonge, Evert, Vandenbroucke-Grauls, Christina M., Savelkoul, Paul H. M., ...

Objectives: During treatment with selective decontamination of the digestive tract (SDD), four multidrug-resistant (MDR) strains, three different Escherichia coli and one Klebsiella pneumoniae, were...

Slaughter Pigs Are Commonly Infected by Closely Related but Distinct Gastric Ulcerative Lesion-Inducing Gastrospirilla

Roosendaal, Robert, Vos, Jan H., Roumen, Thijs, Van Vugt, René, Cattoli, Giovanni, Bart, Aldert, ...

An association between (unculturable) gastrospirillum-like organisms (GLO) and ulcerative lesions in the pars oesophagea in stomachs of swine has been claimed. In dogs GLO detected by microscopy may...

Antigenic Variation of the Class I Outer Membrane Protein in Hyperendemic Neisseria meningitidis Strains in The Netherlands

Bart, Aldert, Dankert, Jacob, Van Der Ende, Arie

Since 1980, the number of cases of meningococcal disease caused by serogroup B isolates with the P1.4 serosubtype has greatly increased in The Netherlands. Screening for this serosubtype in the...

NmeSI Restriction-Modification System Identified by Representational Difference Analysis of a Hypervirulent Neisseria meningitidis Strain

Bart, Aldert, Pannekoek, Yvonne, Dankert, Jacob, Van Der Ende, Arie

Neisseria meningitidis is a gram-negative bacterium that may cause meningitis, sepsis, or both. The increase in the incidence of meningococcal disease in various countries in the past 2 decades is...

Randomly Amplified Polymorphic DNA Genotyping of Serogroup A Meningococci Yields Results Similar to Those Obtained by Multilocus Enzyme Electrophoresis and Reveals New Genotypes

Bart, Aldert, Schuurman, Ilse G. A., Achtman, Mark, Caugant, Dominique A., Dankert, Jacob, Van Der Ende, Arie

Randomly amplified polymorphic DNA (RAPD) genotyping was applied to one representative strain of each of the 84 electrophoretic types (ETs) of Neisseria meningitidis serogroup A previously defined by...

cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct

Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-Dong, ...

The aim of this research was to study whether and to what extent Chinese cagA-positive Helicobacter pylori isolates differ from those in The Netherlands. Analysis of random amplified polymorphic DNA...

A Helicobacter pylori TolC Efflux Pump Confers Resistance to Metronidazole

Van Amsterdam, Karin, Bart, Aldert, Van Der Ende, Arie

In Helicobacter pylori, the contribution of efflux proteins to antibiotic resistance is not well established. As translocases that act in parallel may have overlapping substrate specificities, the...

Widespread Transfer of Resistance Genes between Bacterial Species in an Intensive Care Unit: Implications for Hospital Epidemiology

Naiemi, Nashwan Al, Duim, Birgitta, Savelkoul, Paul H. M., Spanjaard, Lodewijk, De Jonge, Evert, Bart, Aldert, ...

A transferable plasmid encoding SHV-12 extended-spectrum β-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and...

Application of Minimal Sequence Quality Values Prevents Misidentification of the blaSHV Type in Single Bacterial Isolates Carrying Different SHV Extended-Spectrum β-Lactamase Genes

Al Naiemi, Nashwan, Schipper, Kim, Duim, Birgitta, Bart, Aldert

Nucleotide sequencing is the standard molecular method for determination of the β-lactamase gene present in an isolate. Using minimal sequence quality values prevents misidentification of blaSHV...

Plasmid Diversity in Neisseriae†

Van Der Ende, Arie, Bart, Aldert

Horizontal gene transfer constitutes an important force in prokaryotic genome evolution, and it is well-known that plasmids are vehicles for DNA transfer. Chromosomal DNA is frequently exchanged...

Slaughter Pigs Are Commonly Infected by Closely Related but Distinct Gastric Ulcerative Lesion-Inducing Gastrospirilla

Roosendaal, Robert, Vos, Jan H., Roumen, Thijs, Van Vugt, René, Cattoli, Giovanni, Bart, Aldert, ...

An association between (unculturable) gastrospirillum-like organisms (GLO) and ulcerative lesions in the pars oesophagea in stomachs of swine has been claimed. In dogs GLO detected by microscopy may...

Antigenic Variation of the Class I Outer Membrane Protein in Hyperendemic Neisseria meningitidis Strains in The Netherlands

Bart, Aldert, Dankert, Jacob, Van Der Ende, Arie

Since 1980, the number of cases of meningococcal disease caused by serogroup B isolates with the P1.4 serosubtype has greatly increased in The Netherlands. Screening for this serosubtype in the...

NmeSI Restriction-Modification System Identified by Representational Difference Analysis of a Hypervirulent Neisseria meningitidis Strain

Bart, Aldert, Pannekoek, Yvonne, Dankert, Jacob, Van Der Ende, Arie

Neisseria meningitidis is a gram-negative bacterium that may cause meningitis, sepsis, or both. The increase in the incidence of meningococcal disease in various countries in the past 2 decades is...

Randomly Amplified Polymorphic DNA Genotyping of Serogroup A Meningococci Yields Results Similar to Those Obtained by Multilocus Enzyme Electrophoresis and Reveals New Genotypes

Bart, Aldert, Schuurman, Ilse G. A., Achtman, Mark, Caugant, Dominique A., Dankert, Jacob, Van Der Ende, Arie

Randomly amplified polymorphic DNA (RAPD) genotyping was applied to one representative strain of each of the 84 electrophoretic types (ETs) of Neisseria meningitidis serogroup A previously defined by...

cagA-Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct

Van Der Ende, Arie, Pan, Zhi-Jun, Bart, Aldert, Feller, Monique, Xiao, Shu-Dong, ...

The aim of this research was to study whether and to what extent Chinese cagA-positive Helicobacter pylori isolates differ from those in The Netherlands. Analysis of random amplified polymorphic DNA...

A Helicobacter pylori TolC Efflux Pump Confers Resistance to Metronidazole

Van Amsterdam, Karin, Bart, Aldert, Van Der Ende, Arie

In Helicobacter pylori, the contribution of efflux proteins to antibiotic resistance is not well established. As translocases that act in parallel may have overlapping substrate specificities, the...

Widespread Transfer of Resistance Genes between Bacterial Species in an Intensive Care Unit: Implications for Hospital Epidemiology

Naiemi, Nashwan Al, Duim, Birgitta, Savelkoul, Paul H. M., Spanjaard, Lodewijk, De Jonge, Evert, Bart, Aldert, ...

A transferable plasmid encoding SHV-12 extended-spectrum β-lactamase, TEM-116, and aminoglycoside resistance was responsible for two sequential clonal outbreaks of Enterobacter cloacae and...

Application of Minimal Sequence Quality Values Prevents Misidentification of the blaSHV Type in Single Bacterial Isolates Carrying Different SHV Extended-Spectrum β-Lactamase Genes

Al Naiemi, Nashwan, Schipper, Kim, Duim, Birgitta, Bart, Aldert

Nucleotide sequencing is the standard molecular method for determination of the β-lactamase gene present in an isolate. Using minimal sequence quality values prevents misidentification of blaSHV...

Plasmid Diversity in Neisseriae†

Van Der Ende, Arie, Bart, Aldert

Horizontal gene transfer constitutes an important force in prokaryotic genome evolution, and it is well-known that plasmids are vehicles for DNA transfer. Chromosomal DNA is frequently exchanged...

Intragenomic Variation in the Internal Transcribed Spacer 1 Region of Dientamoeba fragilis as a Molecular Epidemiological Marker▿

Bart, Aldert, Van Der Heijden, Harold M., Greve, Sophie, Speijer, Dave, Landman, Wil J., Van Gool, Tom

Dientamoeba fragilis is a parasite that has been recognized to be a causative agent of gastrointestinal symptoms. Because in most studies only some infected persons experience symptoms, it is...

Frequent Occurrence of Human-Associated Microsporidia in Fecal Droppings of Urban Pigeons in Amsterdam, The Netherlands▿

Bart, Aldert, Wentink-Bonnema, Ellen M., Heddema, Edou R., Buijs, Jan, Van Gool, Tom

Human-associated microsporidia were frequently observed in fecal samples of 331 feral pigeons in Amsterdam, The Netherlands, obtained during high- and low-breeding periods. Thirty-six of 331 samples...