Ale Algra

Treatment and outcomes of acute basilar artery occlusion in the Basilar Artery International Cooperation Study (BASICS): a prospective registry study (2009)

Wijman, Christine Ac, Michel, Patrik, Rueckert, Christina M, Weimar, Christian, Mattle, Heinrich P, ...

BACKGROUND: Treatment strategies for acute basilar artery occlusion (BAO) are based on case series and data that have been extrapolated from stroke intervention trials in other cerebrovascular...

Nurses' prediction of volume status after aneurysmal subarachnoid haemorrhage: a prospective cohort study (2008)

Hoff, Reinier G, Rinkel, Gabriel JE, Verweij, Bon H, Algra, Ale, Kalkman, Cor J

Abstract Introduction Patients who have suffered aneurysmal subarachnoid haemorrhage (SAH) often have derangements in blood volume, contributing to poor outcome. To guide fluid management, regular...

Correction: PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN74418480] (2008)

Den Hertog, Heleen M, Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Abstract Background The Paracetamol (Acetaminophen) In Stroke (PAIS) study is a phase III multicenter, double blind, randomized, placebo-controlled clinical trial of high-dose acetaminophen in...

Prevention of glucocorticoid induced osteoporosis with alendronate or alfacalcidol: Relations of change in bone mineral density, bone markers, and calcium homeostasis (2007)

Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...

Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...

Prevention of glucocorticoid induced osteoporosis with alendronate or alfacalcidol: Relations of change in bone mineral density, bone markers, and calcium homeostasis (2007)

Jacobs, Johannes W. G., Lems, Willem F., GEUSENS, Piet, Laan, Roland F. J., Huisman, Anne-Margriet, ...

Objective. To explore the relation of changes in measures of bone turnover and changes in bone mineral density (BMD) of the lumbar spine and total hip over 18 months in a double-blinded, randomized...

Hemicraniectomy after middle cerebral artery infarction with life-threatening Edema trial (HAMLET). Protocol for a randomised controlled trial of decompressive surgery in space-occupying hemispheric infarction (2006)

Hofmeijer, Jeannette, Amelink, G Johan, Algra, Ale, Van Gijn, Jan, Macleod, Malcolm R, Kappelle, L Jaap, ...

Abstract Background Patients with a hemispheric infarct and massive space-occupying brain oedema have a poor prognosis. Despite maximal conservative treatment, the case fatality rate may be as high...

Carotid intima-media thickness and the risk of new vascular events in patients with manifest atherosclerotic disease: the SMART study (2006)

Dijk, Joke M., Graaf, Yolanda Van Der, Bots, Michiel L., Grobbee, Diederick E., Algra, Ale

Aims Carotid intima-media thickness (CIMT) is an independent predictor of vascular events in the general population. Currently, little is known about the relationship between CIMT and new vascular...

Carotid intima-media thickness and the risk of new vascular events in patients with manifest atherosclerotic disease: the SMART study (2006)

Dijk, Joke M., Van Der Graaf, Yolanda, Bots, Michiel L., Grobbee, Diederick E., Algra, Ale

Aims Carotid intima–media thickness (CIMT) is an independent predictor of vascular events in the general population. Currently, little is known about the relationship between CIMT and new vascular...

PAIS: paracetamol (acetaminophen) in stroke; protocol for a randomized, double blind clinical trial. [ISCRTN 74418480] (2005)

Van Breda, Eric J, Van Der Worp, H Bart, Algra, Ale, Kappelle, L Jaap, Van Gijn, Jan, ...

Abstract Background In patients with acute stroke, increased body temperature is associated with large lesion volumes, high case fatality, and poor functional outcome. A 1°C increase in body...

Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study (2005)

Dijk, Joke M., Algra, Ale, Van Der Graaf, Yolanda, Grobbee, Diederick E., Bots, Michiel L.

Aims To study whether arterial stiffness is related to risk of new vascular events in patients with manifest arterial disease and to examine whether this relation varies between patients who differ...

Carotid stiffness and the risk of new vascular events in patients with manifest cardiovascular disease. The SMART study (2005)

Dijk, Joke M., Algra, Ale, Van Der Graaf, Yolanda, Grobbee, Diederick E., Bots, Michiel L.

Aims To study whether arterial stiffness is related to risk of new vascular events in patients with manifest arterial disease and to examine whether this relation varies between patients who differ...

The Metabolic Syndrome is associated with advanced vascular damage in patients with coronary heart disease, stroke, peripheral arterial disease or abdominal aortic aneurysm (2004)

Olijhoek, Jobien K., Van Der Graaf, Yolanda, Banga, Jan-Dirk, Algra, Ale, Rabelink, Ton J., Visseren, Frank L. J., ...

Aims The metabolic syndrome is associated with an increased risk of cardiovascular disease in patients without a cardiovascular history. We investigated whether the metabolic syndrome is related to...

Is clopidogrel superior to aspirin in secondary prevention of vascular disease? (2000)

Algra, Ale, Van Gijn, Jan

Abstract The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel...

Is clopidogrel superior to aspirin in secondary prevention of vascular disease?

Algra, Ale, Gijn, Jan Van

The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus...

Is clopidogrel superior to aspirin in secondary prevention of vascular disease?

Algra, Ale, Van Gijn, Jan

The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus...

Is clopidogrel superior to aspirin in secondary prevention of vascular disease?

Algra, Ale, Van Gijn, Jan

The cornerstone in clinical evidence of the relative efficacy of thienopyridines (clopidogrel, ticlopidine) versus aspirin in the secondary prevention of vascular disease is the Clopidogrel versus...

Caveolin-1 Influences Vascular Protease Activity and Is a Potential Stabilizing Factor in Human Atherosclerotic Disease

Rodriguez-Feo, Juan A., Hellings, Willem E., Moll, Frans L., Van Middelaar, Ben J., Algra, Ale, ...

Caveolin-1 (Cav-1) is a regulatory protein of the arterial wall, but its role in human atherosclerosis remains unknown. We have studied the relationships between Cav-1 abundance, atherosclerotic...

Bilateral carotid artery occlusion with transient or moderately disabling ischaemic stroke: clinical features and long-term outcome

Persoon, Suzanne, Klijn, Catharina J. M., Algra, Ale, Kappelle, L. Jaap

Information on the prognosis of patients with transient ischaemic attack or moderately disabling ischaemic stroke associated with bilateral internal carotid artery (ICA) occlusion is scarce. We...