Alex Ott

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis (2006)

Orion D. Weiner, Maike C. Rentel, Alex Ott, Glenn E. Brown, Mark Jedrychowski, Michael B. Yaffe, ...

The authors describe a group of multiprotein complexes, scaffolded by Hem-1 (a subset of which also contain WAVE2), that are involved in generating and maintaining cellular polarity in neutrophils.

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis (2006)

Orion D. Weiner, Maike C. Rentel, Alex Ott, Glenn E. Brown, Mark Jedrychowski, Michael B. Yaffe, ...

Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis

Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, ...

Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...

Hem-1 Complexes Are Essential for Rac Activation, Actin Polymerization, and Myosin Regulation during Neutrophil Chemotaxis

Weiner, Orion D, Rentel, Maike C, Ott, Alex, Brown, Glenn E, Jedrychowski, Mark, Yaffe, Michael B, ...

Migrating cells need to make different actin assemblies at the cell's leading and trailing edges and to maintain physical separation of signals for these assemblies. This asymmetric control of...