Alex Roher

Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease

Du Yan, Shi, Zhu, Huaijie, Fu, Jin, Yan, Shi Fang, Roher, Alex, Tourtellotte, Wallace W., ...

In Alzheimer disease (AD), neurons are thought to be subjected to the deleterious cytotoxic effects of activated microglia. We demonstrate that binding of amyloid-beta peptide (Aβ) to neuronal...

RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

Arancio, Ottavio, Zhang, Hui Ping, Chen, Xi, Lin, Chang, Trinchese, Fabrizio, Puzzo, Daniela, ...

Receptor for Advanced Glycation Endproducts (RAGE), a multiligand receptor in the immunoglobulin superfamily, functions as a signal-transducing cell surface acceptor for amyloid-beta peptide (Aβ)....

Amyloid-β peptide–Receptor for Advanced Glycation Endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: A proinflammatory pathway in Alzheimer disease

Du Yan, Shi, Zhu, Huaijie, Fu, Jin, Yan, Shi Fang, Roher, Alex, Tourtellotte, Wallace W., ...

In Alzheimer disease (AD), neurons are thought to be subjected to the deleterious cytotoxic effects of activated microglia. We demonstrate that binding of amyloid-beta peptide (Aβ) to neuronal...

RAGE potentiates Aβ-induced perturbation of neuronal function in transgenic mice

Arancio, Ottavio, Zhang, Hui Ping, Chen, Xi, Lin, Chang, Trinchese, Fabrizio, Puzzo, Daniela, ...

Receptor for Advanced Glycation Endproducts (RAGE), a multiligand receptor in the immunoglobulin superfamily, functions as a signal-transducing cell surface acceptor for amyloid-beta peptide (Aβ)....