Taylor, Chris F., Field, Dawn, Sansone, Susanna-Assunta, Aerts, Jan, Apweiler, Rolf, Asburner, Michael, ...
The Minimum Information for Biological and Biomedical Investigations (MIBBI) project provides a resource for those exploring the range of extant minimum information checklists and fosters coordinated...
Extending pathways based on gene lists using InterPro domain signatures (2008)
Hahne, Florian, Mehrle, Alexander, Arlt, Dorit, Poustka, Annemarie, Wiemann, Stefan, Beissbarth, Tim
Abstract Background High-throughput technologies like functional screens and gene expression analysis produce extended lists of candidate genes. Gene-Set Enrichment Analysis is a commonly used and...
The full-ORF clone resource of the German cDNA Consortium (2007)
Bechtel, Stephanie, Rosenfelder, Heiko, Duda, Anny, Schmidt, Christian, Ernst, Ute, Wellenreuther, Ruth, ...
Abstract Background With the completion of the human genome sequence the functional analysis and characterization of the encoded proteins has become the next urging challenge in the post-genome era....
The 3of5 web application for complex and comprehensive pattern matching in protein sequences (2006)
Seiler, Markus, Mehrle, Alexander, Poustka, Annemarie, Wiemann, Stefan
Abstract Background The identification of patterns in biological sequences is a key challenge in genome analysis and in proteomics. Frequently such patterns are complex and highly variable,...
The systematic functional characterisation of Xq28 genes prioritises candidate disease genes (2006)
Kolb-Kokocinski, Anja, Mehrle, Alexander, Bechtel, Stephanie, Simpson, Jeremy C, Kioschis, Petra, Wiemann, Stefan, ...
Abstract Background Well known for its gene density and the large number of mapped diseases, the human sub-chromosomal region Xq28 has long been a focus of genome research. Over 40 of approximately...
The LIFEdb database in 2006 (2006)
Mehrle, Alexander, Rosenfelder, Heiko, Schupp, Ingo, Del Val, Coral, Arlt, Dorit, Hahne, Florian, ...
LIFEdb (http://www.LIFEdb.de) integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb...
High-throughput protein analysis integrating bioinformatics and experimental assays (2004)
Del Val, Coral, Mehrle, Alexander, Falkenhahn, Mechthild, Seiler, Markus, Glatting, Karl-Heinz, Poustka, Annemarie, ...
The wealth of transcript information that has been made publicly available in recent years requires the development of high‐throughput functional genomics and proteomics approaches for its...
Bannasch, Detlev, Mehrle, Alexander, Glatting, Karl-Heinz, Pepperkok, Rainer, Poustka, Annemarie, Wiemann, Stefan
We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full‐length cDNAs generated and sequenced by the German cDNA Consortium with functional...
From ORFeome to Biology: A Functional Genomics Pipeline (2004)
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
Osnabrück, Univ., Diss., 2001.
The preprotein conducting channel at the inner envelope membrane of plastids
Heins, Lisa, Mehrle, Alexander, Hemmler, Roland, Wagner, Richard, Küchler, Michael, Hörmann, Friederike, ...
The preprotein translocation at the inner envelope membrane of chloroplasts so far involves five proteins: Tic110, Tic55, Tic40, Tic22 and Tic20. The molecular function of these proteins has not yet...
Bannasch, Detlev, Mehrle, Alexander, Glatting, Karl-Heinz, Pepperkok, Rainer, Poustka, Annemarie, Wiemann, Stefan
We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on...
High-throughput protein analysis integrating bioinformatics and experimental assays
Del Val, Coral, Mehrle, Alexander, Falkenhahn, Mechthild, Seiler, Markus, Glatting, Karl-Heinz, Poustka, Annemarie, ...
The wealth of transcript information that has been made publicly available in recent years requires the development of high-throughput functional genomics and proteomics approaches for its analysis....
From ORFeome to Biology: A Functional Genomics Pipeline
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
Mehrle, Alexander, Rosenfelder, Heiko, Schupp, Ingo, Del Val, Coral, Arlt, Dorit, Hahne, Florian, ...
LIFEdb () integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an...
The systematic functional characterisation of Xq28 genes prioritises candidate disease genes
Kolb-Kokocinski, Anja, Mehrle, Alexander, Bechtel, Stephanie, Simpson, Jeremy C, Kioschis, Petra, Wiemann, Stefan, ...
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Seiler, Markus, Mehrle, Alexander, Poustka, Annemarie, Wiemann, Stefan
The preprotein conducting channel at the inner envelope membrane of plastids
Heins, Lisa, Mehrle, Alexander, Hemmler, Roland, Wagner, Richard, Küchler, Michael, Hörmann, Friederike, ...
The preprotein translocation at the inner envelope membrane of chloroplasts so far involves five proteins: Tic110, Tic55, Tic40, Tic22 and Tic20. The molecular function of these proteins has not yet...
Bannasch, Detlev, Mehrle, Alexander, Glatting, Karl-Heinz, Pepperkok, Rainer, Poustka, Annemarie, Wiemann, Stefan
We have implemented LIFEdb (http://www.dkfz.de/LIFEdb) to link information regarding novel human full-length cDNAs generated and sequenced by the German cDNA Consortium with functional information on...
High-throughput protein analysis integrating bioinformatics and experimental assays
Del Val, Coral, Mehrle, Alexander, Falkenhahn, Mechthild, Seiler, Markus, Glatting, Karl-Heinz, Poustka, Annemarie, ...
The wealth of transcript information that has been made publicly available in recent years requires the development of high-throughput functional genomics and proteomics approaches for its analysis....
From ORFeome to Biology: A Functional Genomics Pipeline
Wiemann, Stefan, Arlt, Dorit, Huber, Wolfgang, Wellenreuther, Ruth, Schleeger, Simone, Mehrle, Alexander, ...
As several model genomes have been sequenced, the elucidation of protein function is the next challenge toward the understanding of biological processes in health and disease. We have generated a...
Mehrle, Alexander, Rosenfelder, Heiko, Schupp, Ingo, Del Val, Coral, Arlt, Dorit, Hahne, Florian, ...
LIFEdb () integrates data from large-scale functional genomics assays and manual cDNA annotation with bioinformatics gene expression and protein analysis. New features of LIFEdb include (i) an...
The systematic functional characterisation of Xq28 genes prioritises candidate disease genes
Kolb-Kokocinski, Anja, Mehrle, Alexander, Bechtel, Stephanie, Simpson, Jeremy C, Kioschis, Petra, Wiemann, Stefan, ...
The 3of5 web application for complex and comprehensive pattern matching in protein sequences
Seiler, Markus, Mehrle, Alexander, Poustka, Annemarie, Wiemann, Stefan