Alexander Pietras

Hypoxia inducible factor-2alpha in cancer. (2007)

Lofstedt, Tobias, Fredlund, Erik, Holmquist Mengelbier, Linda, Pietras, Alexander, Ovenberger, Marie, Poellinger, Lorenz, ...

Abstract is not available

Arsenic trioxide and neuroblastoma cytotoxicity. (2007)

Pettersson, Helen M, Karlsson, Jenny, Pietras, Alexander, Ora, Ingrid, Pahlman, Sven

Abstract is not available

Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. (2006)

Holmquist-Mengelbier, Linda, Fredlund, Erik, Lofstedt, Tobias, Noguera, Rosa, Navarro, Samuel, Nilsson, Helén, ...

Abstract is not available

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

Sjölund, Jonas, Johansson, Martin, Manna, Sugata, Norin, Carl, Pietras, Alexander, Beckman, Siv, ...

Loss of the tumor suppressor gene von Hippel–Lindau (VHL) plays a key role in the oncogenesis of clear cell renal cell carcinoma (CCRCC). The loss leads to stabilization of the HIF transcription...

HIF-2α maintains an undifferentiated state in neural crest-like human neuroblastoma tumor-initiating cells

Pietras, Alexander, Hansford, Loen M., Johnsson, A. Sofie, Bridges, Esther, Sjölund, Jonas, Gisselsson, David, ...

High hypoxia-inducible factor-2α (HIF-2α) protein levels predict poor outcome in neuroblastoma, and hypoxia dedifferentiates cultured neuroblastoma cells toward a neural crest-like phenotype. Here,...