Alexander W. E. Franz

An Antibody to the Putative Aphid Recognition Site on Cucumber Mosaic Virus Recognizes Pentons but Not Hexons

Bowman, Valorie D., Chase, Elaine S., Franz, Alexander W. E., Chipman, Paul R., Zhang, Xing, Perry, Keith L., ...

Cucumber mosaic virus (CMV), the type member of the genus Cucumovirus (family Bromoviridae), is transmitted by aphids in a nonpersistent manner. Mutagenesis experiments identified the βH-βI loop of...

Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti

Franz, Alexander W. E., Sanchez-Vargas, Irma, Adelman, Zach N., Blair, Carol D., Beaty, Barry J., James, Anthony A., ...

Mosquitoes (Aedes aegypti) were genetically modified to exhibit impaired vector competence for dengue type 2 viruses (DENV-2). We exploited the natural antiviral RNA interference (RNAi) pathway in...

An Antibody to the Putative Aphid Recognition Site on Cucumber Mosaic Virus Recognizes Pentons but Not Hexons

Bowman, Valorie D., Chase, Elaine S., Franz, Alexander W. E., Chipman, Paul R., Zhang, Xing, Perry, Keith L., ...

Cucumber mosaic virus (CMV), the type member of the genus Cucumovirus (family Bromoviridae), is transmitted by aphids in a nonpersistent manner. Mutagenesis experiments identified the βH-βI loop of...

Engineering RNA interference-based resistance to dengue virus type 2 in genetically modified Aedes aegypti

Franz, Alexander W. E., Sanchez-Vargas, Irma, Adelman, Zach N., Blair, Carol D., Beaty, Barry J., James, Anthony A., ...

Mosquitoes (Aedes aegypti) were genetically modified to exhibit impaired vector competence for dengue type 2 viruses (DENV-2). We exploited the natural antiviral RNA interference (RNAi) pathway in...

Dengue Virus Type 2 Infections of Aedes aegypti Are Modulated by the Mosquito's RNA Interference Pathway

Sánchez-Vargas, Irma, Scott, Jaclyn C., Poole-Smith, B. Katherine, Franz, Alexander W. E., Barbosa-Solomieu, Valérie, Wilusz, Jeffrey, ...

A number of studies have shown that both innate and adaptive immune defense mechanisms greatly influence the course of human dengue virus (DENV) infections, but little is known about the innate...