Scientific Commons: Alexander W. Wood

Numerical Range and Generalized B-Algebras (2006)

Tumorigenicity of racemic and optically pure bay region diol epoxides and other derivatives of the nitrogen heterocycle dibenz[a,h]acridine on mouse skin (2001)

Kumar, Subodh, Chang, Richard L., Wood, Alexander W., Xie, Jian Guo, Huang, Mou Tuan, Cui, Xiao Xing, ...

CD-1 female mice were initiated with a single topical application of 500 nmol dibenz[a,h]acridine (DB[a,h]Acr), its racemic trans-1,2-, 3,4-, 8,9- and 10,11-dihydrodiols, racemic...

Tumorigenicity of four optically active bay-region 3,4-diol 1,2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice (2000)

Chang, Richard L., Wood, Alexander W., Kumar, Subodh, Lehr, Roland E., Shirai, Naohiro, Jerina, Donald M., ...

The nitrogen heterocycle dibenz[c,h]acridine (DB[c,h]ACR) and the enantiomers of the diastereomeric pair of bay-region 3,4-diol 1,2-epoxides as well as other bay-region epoxides...

Bacterial and mammalian cell mutagenicity of four optically active bay-region 10,11-diol-8,9-epoxides of the nitrogen heterocycle dibenz (a,h) acridine (1993)

Chang, Richard L., Battista, Silvia, Wong, Ching-Quo, Kumar, Subodh, Kole, Panna L., Sikka, Harish C., ...

The mutagenk activities of the enantiomers of the diastereo-meric pair of bay-region 10, 11-diol-8, 9-epoxides of dibenz-[a,h]acridine (DB[a,h]ACR) were evaluated in histidine-dependent strains of...

Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice (1986)

Smart, Robert C., Huang, Mou-Tuan, Chang, Richard L., Sayer, Jane M., Jerina, Donald M., Wood, Alexander W., ...

The effect of ellagic acid and its more lipophilic derivative, 3-O-decylellagic acid, on the amount of DNA-bound adducts in the epidermis or lung of CD-I mice treated with [3H]benzo-[a]pyrene...

Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by tannic acid, hydroxylated anthraquinones and hydroxylated cinnamic acid derivatives (1985)

Huang, Mou-Tuan, Chang, Richard L., Wood, Alexander W., Newmark, Harold L., Sayer, Jane M., Yagi, Haruhiko, ...

Tannic acid and several hydroxylated anthraquinone and cinnamic acid derivatives inhibited the mutagenic activity of (±)-7β, 8α-dihydroxy-9α, 10α-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene (B[a]P...

Effect of ellagic acid and hydroxylated flavonoids on the tumorigenicity of benzo[a]pyrene and ({+/-})-7{beta}, 8{alpha}-dihydroxy-9{alpha}, 10{alpha}-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene on mouse skin and in the newborn mouse (1985)

Chang, Richard L., Huang, Mou-Tuan, Wood, Alexander W., Wong, Ching-Quo, Newmark, Harold L., Yagi, Haruhiko, ...

Ellagic acid, quercetin and robinetin were tested for their ability to antagonize the tumor-initiating activity of benzo[a]pyrene (B[a]P) and (±)-7β, 8α-dihydroxy-9α,...

Inhibition of the mutagenicity of bay-region diol-epoxides of polycyclic aromatic hydrocarbons by phenolic plant flavonoids (1983)

Huang, Mou-Tuan, Wood, Alexander W., Newmark, Harold L., Sayer, Jane.M., Yagi, Haruhiko, Jerina, Donald M., ...

Myricetin, robinetin and luteolin inhibited the mutagenic activity resulting from the metabolic activation of benzo[a]-pyrene and (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]-pyrene by rat liver...

Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: Exceptional activity of ellagic acid

Wood, Alexander W., Huang, Mou-Tuan, Chang, Richard L., Newmark, Harold L., Lehr, Roland E., Yagi, Haruhiko, ...

Ferulic, caffeic, chlorogenic, and ellagic acids, four naturally occurring plant phenols, inhibit the mutagenicity and cytotoxicity of (±)-7β,8α-dihydroxy-9α,...

Purine Metabolism in Normal and Thioguanine-Resistant Neuroblastoma

Wood, Alexander W., Becker, Michael A., Minna, John D., Seegmiller, J. Edwin

Purine metabolism has been examined in a clonal line of mouse neuroblastoma cells resistant to the cytotoxic effects of 6-thioguanine. Comparative studies in the resistant and parental lines indicate...

Mutagenicity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro-epoxides: Exceptional activity of the bay region 1,2-epoxides

Wood, Alexander W., Chang, Richard L., Levin, Wayne, Lehr, Roland E., Schaefer-Ridder, Maria, Karle, Jean M., ...

Three diastereomeric pairs of diol epoxides, two tetrahydro-epoxides, and the K-region oxide of the polycyclic aromatic hydrocarbon benz[a]anthracene were evaluated for mutagenic activity in strain...