Redundancy of myostatin and growth/differentiation factor 11 function (2009)
McPherron, Alexandra C, Huynh, Thanh V, Lee, Se-Jin
Abstract Background Myostatin (Mstn) and growth/differentiation factor 11 (Gdf11) are highly related transforming growth factor β (TGFβ) family members that play important roles in regulating...
Vita.
Double muscling in cattle due to mutations in the myostatin gene
McPherron, Alexandra C., Lee, Se-Jin
Myostatin (GDF-8) is a member of the transforming growth factor β superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass in mice....
Regulation of myostatin activity and muscle growth
Lee, Se-Jin, McPherron, Alexandra C.
Myostatin is a transforming growth factor-β family member that acts as a negative regulator of skeletal muscle mass. To identify possible myostatin inhibitors that may have applications for...
Suppression of body fat accumulation in myostatin-deficient mice
McPherron, Alexandra C., Lee, Se-Jin
Myostatin is a TGF-β family member that acts as a negative regulator of muscle growth. Mice lacking the myostatin gene (Mstn) have a widespread increase in skeletal muscle mass resulting from a...
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
Wolfman, Neil M., McPherron, Alexandra C., Pappano, William N., Davies, Monique V., Song, Kening, Tomkinson, Kathleen N., ...
Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex...
Double muscling in cattle due to mutations in the myostatin gene
McPherron, Alexandra C., Lee, Se-Jin
Myostatin (GDF-8) is a member of the transforming growth factor β superfamily of secreted growth and differentiation factors that is essential for proper regulation of skeletal muscle mass in mice....
Regulation of myostatin activity and muscle growth
Lee, Se-Jin, McPherron, Alexandra C.
Myostatin is a transforming growth factor-β family member that acts as a negative regulator of skeletal muscle mass. To identify possible myostatin inhibitors that may have applications for...
Suppression of body fat accumulation in myostatin-deficient mice
McPherron, Alexandra C., Lee, Se-Jin
Myostatin is a TGF-β family member that acts as a negative regulator of muscle growth. Mice lacking the myostatin gene (Mstn) have a widespread increase in skeletal muscle mass resulting from a...
Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases
Wolfman, Neil M., McPherron, Alexandra C., Pappano, William N., Davies, Monique V., Song, Kening, Tomkinson, Kathleen N., ...
Myostatin is a transforming growth factor β family member that acts as a negative regulator of skeletal muscle growth. Myostatin circulates in the blood of adult mice in a noncovalently held complex...
Guo, Tingqing, Jou, William, Chanturiya, Tatyana, Portas, Jennifer, Gavrilova, Oksana, McPherron, Alexandra C.
Myostatin (Mstn) is a secreted growth factor expressed in skeletal muscle and adipose tissue that negatively regulates skeletal muscle mass. Mstn−/− mice have a dramatic increase in muscle mass,...