Zeiger, Joanna S., Haberstick, Brett C., Schlaepfer, Isabel, Collins, Allan C., Corley, Robin P., Crowley, Thomas J., ...
Neuronal nicotinic acetylcholine receptors have been implicated in various measures of nicotine dependence. In this paper, we present findings from an exploratory study of single nucleotide...
Organophosphate Toxicity: Genetics, Receptors, and Antidotes (2003)
Studies were completed on the time course of the effect of DFP on brain acetylcholinesterase ACH activity. While brain ACH activity is maximally depressed only 5 minutes after administration, most...
Subunit Michael Marks, Michael J. Marks, Paul Whiteaker, Jennifer Calcaterra, Jerry A. Stitzel, Amy E. Bullock, ...
Nicotinic agonist-stimulated efflux of 86 Rb 1 from mouse brain synaptosomes was monitored continuously by on-line radioactivity detection. The concentration-effect curve following a 5-s stimulation...
Behavioral Consequences of Neurotransmitter Receptor Regulation. (1998)
Wehner, Jeanne M., Collins, Allan C.
The role of brain cholinergic receptors in regulation of physiological and behavioral function was examined by inducing a change in the number of muscarinic cholinergic receptors and studying the...
Ying Lu, Sharon Grady, Michael J. Marks, Marina Picciotto, Jean-Pierre Changeux, Allan C. Collins
Several recent electrophysiological studies have demonstrated that nicotinic agonists stimulate the release of #-aminobutyric acid (GABA) from rodent brain tissue. Our studies used a neurochemical...
A method for fine mapping quantitative trait loci in outbred animal stocks
Mott, Richard, Talbot, Christopher J., Turri, Maria G., Collins, Allan C., Flint, Jonathan
High-resolution mapping of quantitative trait loci (QTL) in animals has proved to be difficult because the large effect sizes detected in crosses between inbred strains are often caused by numerous...
A method for fine mapping quantitative trait loci in outbred animal stocks
Mott, Richard, Talbot, Christopher J., Turri, Maria G., Collins, Allan C., Flint, Jonathan
High-resolution mapping of quantitative trait loci (QTL) in animals has proved to be difficult because the large effect sizes detected in crosses between inbred strains are often caused by numerous...
Identification of a novel nicotinic binding site in mouse brain using [125I]-epibatidine
Whiteaker, Paul, Jimenez, Melissa, McIntosh, J Michael, Collins, Allan C, Marks, Michael J
[125I]-Epibatidine binds to multiple nicotinic acetylcholine receptor (nAChR) subtypes with high affinity. In this study, [125I]-epibatidine was used to label and characterize a novel nAChR subtype...