Amalia Dutra

EGFRvIII expression and PTEN loss synergistically induce chromosomal instability and glial tumors (2009)

Li, Li, Dutra, Amalia, Pak, Evgenia, Labrie, Joseph E., Gerstein, Rachel M., Pandolfi, Pier Paolo, ...

Glioblastomas often show activation of epidermal growth factor receptor (EGFR) and loss of PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor, but it is not known if...

Comparative sequence analyses reveal sites of ancestral chromosomal fusions in the Indian muntjac genome (2008)

Tsipouri, Vicky, Schueler, Mary G, Hu, Sufen, Dutra, Amalia, Pak, Evgenia, ...

Abstract Background Indian muntjac ( Muntiacus muntjak vaginalis ) has an extreme mammalian karyotype, with only six and seven chromosomes in the female and male, respectively. Chinese muntjac (...

Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs (2008)

Gómez-Rodríguez, Julio, Washington, Valance, Cheng, Jun, Dutra, Amalia, Pak, Evgenia, Liu, Pentao, ...

We evaluate here the use of real-time quantitative PCR (q-PCR) as a method for screening for homologous recombinants generated in mammalian cells from either conventional gene-targeting constructs or...

Xcat, a novel mouse model for Nance-Horan syndrome inhibits expression of the cytoplasmic-targeted Nhs1 isoform (2006)

Huang, Kristen M., Wu, Junhua, Duncan, Melinda K., Moy, Chris, Dutra, Amalia, Favor, Jack, ...

Nance–Horan syndrome (NHS) is an X-linked disorder characterized by congenital cataracts, dental anomalies, dysmorphic features and mental retardation. A recent report suggests that the novel gene...

Xcat, a novel mouse model for Nance Horan Syndrome inhibits expression of the cytoplasmic-targeted Nhs1 isoform (2005)

Huang, Kristen M., Wu, Junhua, Duncan, Melinda K., Moy, Chris, Dutra, Amalia, Favor, Jack, ...

Nance Horan Syndrome (NHS) is an X-linked disorder characterized by congenital cataracts, dental anomalies, dysmorphic features and mental retardation. A recent report suggests that the novel gene...

Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft (2002)

Aldosari,Naji, Wiltshire,Rodney N., Dutra,Amalia, Schrock,Evelin, McLendon,Roger E., Friedman,Henry S., ...

Cell lines and xenografts derived from medulloblastomas are useful tools to investigate the chromosomal changes in these tumors. Here we used G-banding, fluorescence in situ hybridization (FISH),...

A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes (2002)

Rozenblum, Ester, Vahteristo, Pia, Sandberg, Therese, Bergthorsson, Jon Thor, Syrjakoski, Kirsi, Weaver, Don, ...

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Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft (2002)

Aldosari, Naji, Wiltshire, Rodney N., Dutra, Amalia, Schrock, Evelin, McLendon, Roger E., Friedman, Henry S., ...

Cell lines and xenografts derived from medulloblastomas are useful tools to investigate the chromosomal changes in these tumors. Here we used G-banding, fluorescence in situ hybridization (FISH),...

Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft (2002)

Aldosari, Naji, Wiltshire, Rodney N., Dutra, Amalia, Schrock, Evelin, McLendon, Roger E., Friedman, Henry S., ...

Cell lines and xenografts derived from medulloblastomas are useful tools to investigate the chromosomal changes in these tumors. Here we used G-banding, fluorescence in situ hybridization (FISH),...

Cloning and Genomic Organization of the Mouse Gene Slc23a1 Encoding a Vitamin C Transporter (2000)

Gispert, Suzana, Dutra, Amalia, Lieberman, Andrew, Friedlich, Dan, Nussbaum, Robert L.

Vitamin C is known to exist in particularly high concentrations in brain tissue, and its free radical scavenging function is thought to represent a major antioxidative defense system. We have cloned,...

Contig Map of the Parkinson's Disease Region on 4q21-q23 (1998)

Lavedan, Christian, Dehejia, Anindya, Pike, Brian, Dutra, Amalia, Leroy, Elisabeth, Ide, Susan E., ...

We have constructed a yeast artificial chromosome contig (YAC) map of human chromosome 4q21-q23 across the Parkinson's disease region by combining molecular and fluorescence in situ hybridization...

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion

Lozier, Jay N., Dutra, Amalia, Pak, Evgenia, Zhou, Nan, Zheng, Zhili, Nichols, Timothy C., ...

In the Chapel Hill colony of factor VIII-deficient dogs, abnormal sequence (ch8, for canine hemophilia 8, GenBank no. AF361485) follows exons 1–22 in the factor VIII transcript in place of exons...

Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast

Kouprina, Natalay, Leem, Sun-Hee, Solomon, Greg, Ly, Albert, Koriabine, Maxim, Otstot, John, ...

The reported draft human genome sequence includes many contigs that are separated by gaps of unknown sequence. These gaps may be due to chromosomal regions that are not present in the Escherichia...

The Chapel Hill hemophilia A dog colony exhibits a factor VIII gene inversion

Lozier, Jay N., Dutra, Amalia, Pak, Evgenia, Zhou, Nan, Zheng, Zhili, Nichols, Timothy C., ...

In the Chapel Hill colony of factor VIII-deficient dogs, abnormal sequence (ch8, for canine hemophilia 8, GenBank no. AF361485) follows exons 1–22 in the factor VIII transcript in place of exons...

Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast

Kouprina, Natalay, Leem, Sun-Hee, Solomon, Greg, Ly, Albert, Koriabine, Maxim, Otstot, John, ...

The reported draft human genome sequence includes many contigs that are separated by gaps of unknown sequence. These gaps may be due to chromosomal regions that are not present in the Escherichia...

Comprehensive molecular cytogenetic investigation of chromosomal abnormalities in human medulloblastoma cell lines and xenograft.

Aldosari, Naji, Wiltshire, Rodney N., Dutra, Amalia, Schrock, Evelin, McLendon, Roger E., Friedman, Henry S., ...

Cell lines and xenografts derived from medulloblastomas are useful tools to investigate the chromosomal changes in these tumors. Here we used G-banding, fluorescence in situ hybridization (FISH),...

Advantages of q-PCR as a method of screening for gene targeting in mammalian cells using conventional and whole BAC-based constructs

Gómez-Rodríguez, Julio, Washington, Valance, Cheng, Jun, Dutra, Amalia, Pak, Evgenia, Liu, Pentao, ...

We evaluate here the use of real-time quantitative PCR (q-PCR) as a method for screening for homologous recombinants generated in mammalian cells from either conventional gene-targeting constructs or...

TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans

Washington, A. Valance, Gibot, Sébastien, Acevedo, Ismael, Gattis, James, Quigley, Laura, Feltz, Robert, ...

Triggering receptor expressed on myeloid cells–like (TREM-like) transcript-1 (TLT-1), a type 1 single Ig domain orphan receptor specific to platelet and megakaryocyte α-granules, relocates to the...

Comparative sequence analyses reveal sites of ancestral chromosomal fusions in the Indian muntjac genome

Tsipouri, Vicky, Schueler, Mary G, Hu, Sufen, Dutra, Amalia, Pak, Evgenia, Riethman, Harold, ...

Comparative mapping and sequencing was used to characterize the sites of ancestral chromosomal fusions in the Indian muntjac genome.