A second major histocompatibility complex susceptibility locus for multiple sclerosis (2007)
Gregory, Simon G, Barcellos, Lisa F, Walton, Amie, ...
Objective: Variation in the major histocompatibility complex (MHC) on chromosome 6p21 is known to influence susceptibility to multiple sclerosis with the strongest effect originating from the...
Walton, Amie, Gray, Julia, Compston, Alastair, Sawcer, Stephen
Afdeling Experimentele neurologie.
CD24 Ala/Val polymorphism and multiple sclerosis (2006)
Maranian, Melanie, Walton, Amie, Yeo, Tai Wai, Ban, Maria, Gray, Julia, ...
CD24 is expressed on a broad range of cells in the immune and central nervous systems and appears to be required for development of experimental autoimmune encephalomyelitis in mice. Association of a...
No alterations in alpha-synuclein gene dosage observed in sporadic Parkinson's disease (2006)
Foltynie, Thomas, Brown, Joanne, Maranian, Melanie, Walton, Amie, ...
Investigation of the Role of Mitochondrial DNA in Multiple Sclerosis Susceptibility
Ban, Maria, Elson, Joanna, Walton, Amie, Turnbull, Douglas, Compston, Alastair, Chinnery, Patrick, ...
Several lines of evidence suggest that mitochondrial genetic factors may influence susceptibility to multiple sclerosis. To explore this hypothesis further, we re-sequenced the mitochondrial genome...
Jones, Joanne L., Phuah, Chia-Ling, Cox, Amanda L., Thompson, Sara A., Ban, Maria, Shawcross, Jacqueline, ...
Phase II clinical trials revealed that the lymphocyte-depleting humanized monoclonal antibody alemtuzumab (Campath-1H) is highly effective in the treatment of early relapsing-remitting multiple...