Amilcar Flores-Morales

Exploring hepatic hormone actions using a compilation of gene expression profiles (2005)

Ståhlberg, Nina, Merino, Roxana, Hernández, Luis, Fernández-Pérez, Leandro, Sandelin, Albin, Engström, Pär, ...

Abstract Background Microarray analysis is attractive within the field of endocrine research because regulation of gene expression is a key mechanism whereby hormones exert their actions. Knowledge...

Gene Expression Profiling of the Effects of Castration and Estrogen Treatment in the Rat Uterus1 (2003)

Xuxia Wu, See-Tong Pang, Lena Sahlin, Agneta Blanck, Gunnar Norstedt, Amilcar Flores-Morales

The development and functions of female reproductive tissues are regulated by the actions of two major sex steroid hormones, estrogen and progesterone. To investigate estrogen-dependent gene...

Identification of genes with higher expression in human uterine leiomyomas than in the corresponding myometrium (2002)

Wu, Xuxia, Blanck, Agneta, Norstedt, Gunnar, Sahlin, Lena, Flores-Morales, Amilcar

We used a PCR-based subtraction method, representational difference analysis of cDNA (cDNA–RDA), to identify genes with a higher expression in leiomyomas in comparison with the corresponding...

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Greenhalgh, Christopher J., Rico-Bautista, Elizabeth, Lorentzon, Mattias, Thaus, Anne L., Morgan, Phillip O., Willson, Tracy A., ...

Mice deficient in SOCS2 display an excessive growth phenotype characterized by a 30–50% increase in mature body size. Here we show that the SOCS2–/– phenotype is dependent upon the presence of...

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Greenhalgh, Christopher J., Rico-Bautista, Elizabeth, Lorentzon, Mattias, Thaus, Anne L., Morgan, Phillip O., Willson, Tracy A., ...

Mice deficient in SOCS2 display an excessive growth phenotype characterized by a 30–50% increase in mature body size. Here we show that the SOCS2–/– phenotype is dependent upon the presence of...

SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation

Hu, Jin, Winqvist, Ola, Flores-Morales, Amilcar, Wikström, Ann-Charlotte, Norstedt, Gunnar

Dendritic cells (DCs) are highly specific antigen presenting cells, which link innate and adaptive immune responses and participate in protecting hosts from invading pathogens. DCs can be generated...