Amir Ali Abbasi, Debbie K. Goode, Saneela Amir, Karl-Heinz Grzeschik
Background: In vertebrates the “SONIC HEDGEHOG” signalling pathway has been implicated in cell-fate determination, proliferation and the patterning of many different cell types and organs. As the...
GLI genes: Cis-Acting Regulatory Elements (2008)
Towards the elucidation of genetic mechanisms, by which the transcription of GLI genes is regulated during early embryonic development, in this study one of the members of this family, i.e. human...
Article type Hypothesis (2008)
Amir Ali Abbasi, Amir Ali Abbasi
PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Are we degenerate tetraploids? More genomes, new facts
Human GLI3 Intragenic Conserved Non-Coding Sequences Are Tissue-Specific Enhancers
Abbasi, Amir Ali, Paparidis, Zissis, Malik, Sajid, Goode, Debbie K., Callaway, Heather, Elgar, Greg, ...
The zinc-finger transcription factor GLI3 is a key regulator of development, acting as a primary transducer of Sonic hedgehog (SHH) signaling in a combinatorial context dependent fashion controlling...