Amy Hin Yan Tong

A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability (2005)

Budd, Martin E., Tong, Amy Hin Yan, Polaczek, Piotr, Peng, Xiao, Boone, Charles, Campbell, Judith L.

To elucidate the network that maintains high fidelity genome replication, we have introduced two conditional mutant alleles of DNA2, an essential DNA replication gene, into each of the approximately...

Synthetic Lethal Analysis Implicates Ste20p, a p21-activated Protein Kinase, in Polarisome ActivationD⃞

Goehring, April S., Mitchell, David A., Tong, Amy Hin Yan, Keniry, Megan E., Boone, Charles, Sprague, George F.

The p21-activated kinases Ste20p and Cla4p carry out undefined functions that are essential for viability during budding in Saccharomyces cerevisiae. To gain insight into the roles of Ste20p, we have...

Interaction between a Ras and a Rho GTPase Couples Selection of a Growth Site to the Development of Cell Polarity in Yeast

Kozminski, Keith G., Beven, Laure, Angerman, Elizabeth, Tong, Amy Hin Yan, Boone, Charles, Park, Hay-Oak

Polarized cell growth requires the coupling of a defined spatial site on the cell cortex to the apparatus that directs the establishment of cell polarity. In the budding yeast Saccharomyces...

A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability

Budd, Martin E, Tong, Amy Hin Yan, Polaczek, Piotr, Peng, Xiao, Boone, Charles, Campbell, Judith L

To elucidate the network that maintains high fidelity genome replication, we have introduced two conditional mutant alleles of DNA2, an essential DNA replication gene, into each of the approximately...

Synthetic Lethal Analysis Implicates Ste20p, a p21-activated Protein Kinase, in Polarisome ActivationD⃞

Goehring, April S., Mitchell, David A., Tong, Amy Hin Yan, Keniry, Megan E., Boone, Charles, Sprague, George F.

The p21-activated kinases Ste20p and Cla4p carry out undefined functions that are essential for viability during budding in Saccharomyces cerevisiae. To gain insight into the roles of Ste20p, we have...

Interaction between a Ras and a Rho GTPase Couples Selection of a Growth Site to the Development of Cell Polarity in Yeast

Kozminski, Keith G., Beven, Laure, Angerman, Elizabeth, Tong, Amy Hin Yan, Boone, Charles, Park, Hay-Oak

Polarized cell growth requires the coupling of a defined spatial site on the cell cortex to the apparatus that directs the establishment of cell polarity. In the budding yeast Saccharomyces...

A Network of Multi-Tasking Proteins at the DNA Replication Fork Preserves Genome Stability

Budd, Martin E, Tong, Amy Hin Yan, Polaczek, Piotr, Peng, Xiao, Boone, Charles, Campbell, Judith L

To elucidate the network that maintains high fidelity genome replication, we have introduced two conditional mutant alleles of DNA2, an essential DNA replication gene, into each of the approximately...

Inorganic Phosphate Deprivation Causes tRNA Nuclear Accumulation via Retrograde Transport in Saccharomyces cerevisiae

Hurto, Rebecca L., Tong, Amy Hin Yan, Boone, Charles, Hopper, Anita K.

Nuclear export of tRNA is an essential eukaryotic function, yet the one known yeast tRNA nuclear exporter, Los1, is nonessential. Moreover recent studies have shown that tRNAs can move retrograde...

Sequential and Distinct Roles of the Cadherin Domain-containing Protein Axl2p in Cell Polarization in Yeast Cell Cycle

Gao, Xiang-Dong, Sperber, Lauren M., Kane, Steven A., Tong, Zongtian, Tong, Amy Hin Yan, Boone, Charles, ...

Polarization of cell growth along a defined axis is essential for the generation of cell and tissue polarity. In the budding yeast Saccharomyces cerevisiae, Axl2p plays an essential role in...

Ybp2 Associates with the Central Kinetochore of Saccharomyces cerevisiae and Mediates Proper Mitotic Progression

Ohkuni, Kentaro, Abdulle, Rashid, Tong, Amy Hin Yan, Boone, Charles, Kitagawa, Katsumi

The spindle checkpoint ensures the accurate segregation of chromosomes by monitoring the status of kinetochore attachment to microtubules. Simultaneous mutations in one of several kinetochore and...

The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi

Gillingham, Alison K., Tong, Amy Hin Yan, Boone, Charles, Munro, Sean

Rud3p is a coiled-coil protein of the yeast cis-Golgi. We find that Rud3p is localized to the Golgi via a COOH-terminal domain that is distantly related to the GRIP domain that recruits several...

Genome-wide, as opposed to local, antisilencing is mediated redundantly by the euchromatic factors Set1 and H2A.Z

Venkatasubrahmanyam, Shivkumar, Hwang, William W., Meneghini, Marc D., Tong, Amy Hin Yan, Madhani, Hiten D.

In Saccharomyces cerevisiae, several nonessential mechanisms including histone variant H2A.Z deposition and transcription-associated histone H3 methylation antagonize the local spread of...