Eduardo Sontag, Anatoly Kiyatkin, Boris N. Kholodenko
Inferring dynamic architecture of cellular
Sontag, Eduardo, Kiyatkin, Anatoly, Kholodenko, Boris N.
Motivation: High-throughput technologies have facilitated the acquisition of large genomics and proteomics data sets. However, these data provide snapshots of cellular behavior, rather than help us...
Sontag, Eduardo, Kiyatkin, Anatoly, Kholodenko, Boris N.
Motivation: High-throughput technologies have facilitated the acquisition of large genomics and proteomics datasets. However, these data provide snapshots of cellular behavior, rather than help us...
Sontag, Eduardo, Kiyatkin, Anatoly, Kholodenko, Boris N.
Motivation: High-throughput technologies have facilitated the acquisition of large genomics and proteomics data sets. However, these data provide snapshots of cellular behavior, rather than help us...
Untangling the wires: A strategy to trace functional interactions in signaling and gene networks
Kholodenko, Boris N., Kiyatkin, Anatoly, Bruggeman, Frank J., Sontag, Eduardo, Westerhoff, Hans V., Hoek, Jan B.
Emerging technologies have enabled the acquisition of large genomics and proteomics data sets. However, current methodologies for analysis do not permit interpretation of the data in ways that...
Untangling the wires: A strategy to trace functional interactions in signaling and gene networks
Kholodenko, Boris N., Kiyatkin, Anatoly, Bruggeman, Frank J., Sontag, Eduardo, Westerhoff, Hans V., Hoek, Jan B.
Emerging technologies have enabled the acquisition of large genomics and proteomics data sets. However, current methodologies for analysis do not permit interpretation of the data in ways that...
Systems-level interactions between insulin–EGF networks amplify mitogenic signaling
Borisov, Nikolay, Aksamitiene, Edita, Kiyatkin, Anatoly, Legewie, Stefan, Berkhout, Jan, Maiwald, Thomas, ...
Crosstalk mechanisms have not been studied as thoroughly as individual signaling pathways. We exploit experimental and computational approaches to reveal how a concordant interplay between the...