Anders Lobner-Olesen

DnaC inactivation in Escherichia coli K-12 induces the SOS response and expression of nucleotide biosynthesis genes (2008)

Lobner-Olesen, Anders, Slominska-Wojewodzka, Monika, Hansen, Flemming G., Marinus, Martin G.

BACKGROUND: Initiation of chromosome replication in E. coli requires the DnaA and DnaC proteins and conditionally-lethal dnaA and dnaC mutants are often used to synchronize cell populations....

Dam methyltransferase is required for stable lysogeny of the Shiga toxin (Stx2)-encoding bacteriophage 933W of enterohemorrhagic Escherichia coli O157:H7 (2007)

Murphy, Kenan C., Ritchie, Jennifer M., Waldor, Matthew K., Lobner-Olesen, Anders, Marinus, Martin G.

Shiga toxin 2 (Stx2), one of the principal virulence factors of enterohemorrhagic Escherichia coli, is encoded by 933W, a lambda-like prophage. 933W prophage induction contributes to Stx2 production,...

Increased adherence and actin pedestal formation by dam-deficient enterohaemorrhagic Escherichia coli O157:H7 (2007)

Campellone, Kenneth Geno, Roe, Andrew J., Lobner-Olesen, Anders, Murphy, Kenan C., Magoun, Loranne, Brady, Michael J., ...

Enterohaemorrhagic Escherichia coli (EHEC) are highly infectious pathogens capable of causing severe diarrhoeal illnesses. As a critical step during their colonization, EHEC adhere intimately to...

Hda-mediated inactivation of the DnaA protein and dnaA gene autoregulation act in concert to ensure homeostatic maintenance of the Escherichia coli chromosome (2006)

Riber, Leise, Olsson, Jan A., Jensen, Rasmus B., Skovgaard, Ole, Dasgupta, Santanu, Marinus, Martin G., ...

Initiation of DNA replication in Eschericia coli requires the ATP-bound form of the DnaA protein. The conversion of DnaA-ATP to DnaA-ADP is facilitated by a complex of DnaA, Hda (homologous to DnaA),...

Role of SeqA and Dam in Escherichia coli gene expression: a global/microarray analysis (2003)

Lobner-Olesen, Anders, Marinus, Martin G., Hansen, Flemming G.

High-density oligonucleotide arrays were used to monitor global transcription patterns in Escherichia coli with various levels of Dam and SeqA proteins. Cells lacking Dam methyltransferase showed a...

Growth-rate-dependent transcription initiation from the dam P2 promoter (1995)

Rasmussen, Lene Juel, Lobner-Olesen, Anders, Marinus, Martin G.

Transcription of the dam gene in Escherichia coli is dependent on growth rate. Using single-copy promoter::lacZYA fusions we found that of the five promoter regions which affect dam expression, only...

Novel growth rate control of dam gene expression in Escherichia coli (1994)

Rasmussen, Lene Juel, Marinus, Martin G., Lobner-Olesen, Anders

Transcription of the dam gene in Escherichia coli is growth rate regulated by a mechanism distinct from that used for ribosomal RNA gene promoters. Single-copy operon fusions to lacZ indicated that...

Expression of the Escherichia coli dam gene (1992)

Lobner-Olesen, Anders, Boye, Erik, Marinus, Martin G.

The Escherichia coli dam gene and upstream sequences were cloned from the Kohara phage 4D4. Five promoters were found to contribute to dam gene transcription. P1 and P2 (the major promoter) were...

Quantitation of Dam methyltransferase in Escherichia coli (1992)

Boye, Erik, Marinus, Martin G., Lobner-Olesen, Anders

An antiserum against Escherichia coli Dam methyltransferase has been developed in rabbits and employed to detect and quantitate the enzyme in immunoblots. A wild-type, rapidly growing E. coli cell...

Identification of the gene (aroK) encoding shikimic acid kinase I of Escherichia coli (1992)

Lobner-Olesen, Anders, Marinus, Martin G.

DNA sequence analysis has revealed that an unidentified open reading frame (ufr1) is present immediately preceding the aroB gene of Escherichia coli. The predicted protein product of urf1 contains a...